Hotels in Southeast Missouri

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Where to stay in Southeast Missouri?

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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Top landmarks in Southeast Missouri

Learn more about Southeast Missouri

Southeast Missouri is well-known for its wineries and riverfront while attractions include Sam A. Baker State Park and K Bridge Recreation Area. This family-friendly city has something for everyone including its university life, restaurants, and sights like Lake Wappapello State Park and Clearwater Lake.

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Frequently asked questions

Why should I book my Southeast Missouri accommodation with Hotels.com?
There are plenty of reasons to book your Southeast Missouri travel with us: our free cancellations on selected hotels gives you the flexibility you're looking for, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.

Find out more about Southeast Missouri

Find out more about Southeast Missouri

Where Rivers Flow and Wildflowers Bloom: Discover Southeast Missouri's Hidden Charms

Discover the enchanting charm of Southeast Missouri, where the lush landscapes along the Mississippi River beckon adventurers and nature lovers alike. Immerse yourself in the serene beauty of the Ozark foothills, explore vibrant wildflower trails, and experience the rich heritage of the region at local festivals and historic sites. Don’t miss the lively atmosphere at Southeast Missouri State University, where culture and community thrive. With cozy accommodations and delightful dining options, this off-the-beaten-path gem offers a perfect blend of outdoor escapades and cultural experiences, making it a memorable escape for every traveler.

Discover great hotels near Southeast Missouri

Southeast Missouri offers a variety of hotel accommodations to suit different preferences and budgets. From modern hotels in bustling Cape Girardeau to cozy inns in scenic areas, travelers can find comfortable rooms and convenient amenities. Whether you’re seeking proximity to attractions or peaceful surroundings, there are plenty of options available. Here are some of the best hotels near Southeast Missouri that our travelers love:

  1. Madison Inn LodgeOpens in a new window: Madison Inn Lodge is a charming 2.5-star motel that caters to travelers seeking a comfortable and pet-friendly experience. With a focus on providing business-themed amenities, this property features various facilities designed to enhance your stay. The welcoming atmosphere is complemented by its pet policy, making it an appealing choice for those traveling with furry companions. Guests appreciate the thoughtful touches and accommodating environment, making it a favored choice for those who value convenience and a pleasant atmosphere during their travels.
  2. Shepherd Mountain InnOpens in a new window: Shepherd Mountain Inn is a well-appointed 2.5-star hotel that excels in offering a blend of comfort and functionality for business travelers. This property features multiple meeting rooms, ensuring seamless planning and execution of professional gatherings. Its sophisticated design and high-quality amenities create an inviting atmosphere for those on the go. The hotel's commitment to providing an exceptional experience is reflected in the positive sentiments shared by travelers, highlighting its appeal for individuals who prioritize efficiency and comfort during their business trips.

Things to do near Southeast Missouri

Southeast Missouri enchants visitors with its scenic rivers, vibrant wildflower fields, and lush forests. Explore winding trails, enjoy lakeside picnics, or relax on sandy beaches. Outdoor enthusiasts will find endless opportunities for fishing, hiking, and birdwatching, all while soaking in the region's natural beauty and charm.

  • Madison County CourthouseOpens in a new window – Step into the past at the Madison County Courthouse, a historic civic government building that showcases stunning architecture and rich history. As you wander around, take in the intricate details and craftsmanship that make this landmark a standout in the area. It's a great spot for photography enthusiasts and those who appreciate local heritage, all while being surrounded by the vibrancy of the community.
  • Millstream Gardens Conservation AreaOpens in a new window – Nature lovers will find solace at Millstream Gardens Conservation Area, a beautiful reserve that invites exploration. Stroll along the scenic trails lined with blooming flowers and listen to the soothing sounds of the river as it flows through the landscape. It's an ideal location for a peaceful hike, a picnic, or simply enjoying the serene beauty of the outdoors. Don't forget your camera; the natural scenery is breathtaking!

5 tips for savvy savings when booking a hotel near Southeast Missouri

  1. Book for the cheapest times: The most budget-friendly time to visit Southeast Missouri is during January, November, and December, when hotel prices tend to be lower. For a great value for money experience, staying for at least 2 to 3 days is recommended to fully explore the area's significant landmarks, cultural sites, and historical attractions. During your visit, you can enjoy family-friendly activities, charming cafes, delightful dining options, local wineries, scenic rivers, and the friendly atmosphere offered by the community. This timeframe could provide an affordable getaway while discovering the beauty of Southeast Missouri’s culture and history.
  2. Look for last-minute deals on Hotels.com: To discover last-minute deals to Southeast Missouri, visit the DealsOpens in a new window or Last-Minute DealsOpens in a new window sections on Hotels.com, where you may find discounted hotel rates as your travel date approaches. Consider enabling email alerts or push notifications to stay informed about flash sales and special promotions, helping you save on your trip. Additionally, the Smart ShoppingOpens in a new window tool available via the app allows you to compare hotel prices and amenities, so you could find the best options. With these features, you’re more likely to be notified of any price drops or room availability, making it easier to book a spontaneous getaway.
  3. Be flexible with dates: Prices can fluctuate based on factors like the hotel's location, star rating, and the time of year. Being flexible with your travel dates could help you find better rates for your stay near a Southeast Missouri hotel. If you're interested in a unique experience, boutique hotels often provide a more personalized atmosphere and may offer better value. When you book through Hotels.com, we’ll inform you if the price for your chosen dates is above or below the average. If the price is higher than usual, we’ll recommend more budget-friendly dates, which could help you secure a better deal.
  4. Consider your location: Staying close to major attractions or city centers can be convenient, but it often comes with a higher price tag. For more budget-friendly options, you might want to look for hotels in less central areas or neighborhoods, striking a balance between cost and accessibility to the sites you want to visit. Independent hotels located a bit further out are usually more likely to be affordable and can offer a more authentic experience.
  5. Become a Member: Join our membership for free and start planning your next getaway near Southeast Missouri! Enjoy exclusive member prices and save on over 100,000 hotels worldwide. As a member, you'll have the opportunity to advance through tiers, unlocking fantastic perks such as complimentary room upgrades (subject to availability) and discounts on food and beverages at select VIP Access properties. Don't miss out on these amazing benefits—sign up today and elevate your travel experience!

Best time to go to Southeast Missouri

Southeast Missouri has a varied climate due to its size, so the best time to visit depends on the region and your preferences for weather and crowds. If you’re looking to soak up the lively atmosphere in Southeast Missouri, May to July are the peak months to visit, bustling with fellow travelers. During this peak period, the weather is mostly sunny, with light rainfall. However, if you prefer a more relaxed experience, January, February, and December are perfect for a quieter getaway, marked by light rainfall and mostly sunny conditions.

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