Hotels in Puxico

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Where to stay in Puxico?

Properties are selected based on real traveler reviews and popularity among guests who’ve booked a night in Puxico on Hotels.com. These Puxico hotels consistently deliver on comfort, location and traveler experience. Last updated on .

Drury Inn & Suites Poplar Bluff

Drury Inn & Suites Poplar Bluff
3.0 star property
Poplar Bluff
9.4 out of 10, Exceptional, (1,001 reviews)
Minutes from North Main Street Historic District, this peaceful hotel offers 2 swimming pools and fitness options. Guests rave about the quiet atmosphere, complimentary breakfast, and exceptionally helpful staff. Free WiFi and parking enhance your comfortable Missouri stay.
$94 nightly
The price is $106
Jul 23 - Jul 24
Total with taxes and fees
Drury Inn & Suites Poplar Bluff

Hampton Inn Poplar Bluff

Hampton Inn Poplar Bluff
2.5 star property
Poplar Bluff
9.4 out of 10, Exceptional, (899 reviews)
Wake up to a tasty free breakfast at this Poplar Bluff hotel with indoor pool and fitness center. Just minutes from local attractions like Margaret Harwell Art Museum, you'll appreciate the free WiFi, complimentary parking, and attentive staff that guests consistently praise.
$93 nightly
The price is $105
Aug 2 - Aug 3
Total with taxes and fees
Hampton Inn Poplar Bluff

Motel 6 Poplar Bluff, MO

Motel 6 Poplar Bluff, MO
2.0 star property
Poplar Bluff
8.0 out of 10, Very Good, (1,002 reviews)
This budget-friendly motel offers free WiFi and parking with clean rooms appreciated by travelers. Helpful staff provide 24-hour service while the convenient location puts you near cultural attractions like the Margaret Harwell Art Museum.
$78 nightly
The price is $88
Jul 24 - Jul 25
Total with taxes and fees
Motel 6 Poplar Bluff, MO

Fairfield Inn & Suites by Marriott Poplar Bluff

Fairfield Inn & Suites by Marriott Poplar Bluff
3.0 star property
Poplar Bluff
9.4 out of 10, Exceptional, (937 reviews)
Situated near Poplar Bluff Station, this hotel offers both convenience and comfort with its 24-hour fitness center and refreshing indoor pool. Explore nearby North Main Street Historic District after enjoying the free breakfast and WiFi.
$101 nightly
The price is $114
Jul 26 - Jul 27
Total with taxes and fees
Fairfield Inn & Suites by Marriott Poplar Bluff

Holiday Inn Poplar Bluff by IHG

Holiday Inn Poplar Bluff by IHG
3.0 star property
Poplar Bluff
8.8 out of 10, Excellent, (750 reviews)
Discover quiet comfort at this Poplar Bluff hotel with an indoor swimming pool and Italian restaurant. Near North Main Street Historic District, you'll enjoy helpful staff service, in-room refrigerators, and fitness facilities.
$83 nightly
The price is $94
Aug 2 - Aug 3
Total with taxes and fees
Holiday Inn Poplar Bluff by IHG

Hampton Inn By Hilton Dexter

Hampton Inn By Hilton Dexter
2.5 star property
Dexter
9.8 out of 10, Exceptional, (50 reviews)
$98 nightly
The price is $110
Jul 26 - Jul 27
Total with taxes and fees
Hampton Inn By Hilton Dexter

Super 8 by Wyndham Poplar Bluff Missouri

Super 8 by Wyndham Poplar Bluff Missouri
2.0 star property
Poplar Bluff
6.6 out of 10, (656 reviews)
This Missouri motel offers practical comforts with free WiFi, parking, and on-the-go breakfast daily. Just minutes from North Main Street Historic District and the art museum, it provides convenient access to local attractions.
$68 nightly
The price is $77
Jul 24 - Jul 25
Total with taxes and fees
Super 8 by Wyndham Poplar Bluff Missouri

EC Reed's Mercantile and Hotel

EC Reed's Mercantile and Hotel
3.0 star property
Marble Hill
9.6 out of 10, Exceptional, (102 reviews)
Adventure seekers can explore nearby hiking trails, kayaking, and rafting, then return to this welcoming hotel. Enjoy free continental breakfast, WiFi, and parking, plus exceptional service from the staff that guests consistently praise.
$96 nightly
The price is $105
Aug 15 - Aug 16
Total with taxes and fees
EC Reed's Mercantile and Hotel

Travelodge by Wyndham Dexter

Travelodge by Wyndham Dexter
2.0 star property
Dexter
7.6 out of 10, Good, (415 reviews)
Walking distance to The Heritage House and Keller Veteran Memorial, this hotel boasts free WiFi and parking. Enjoy American cuisine at Penny's Diner, open for 3 daily meals, plus 24-hour front desk service for round-the-clock assistance.
$87 nightly
The price is $98
Jul 19 - Jul 20
Total with taxes and fees
Travelodge by Wyndham Dexter

Dexter Inn

Dexter Inn
2.5 star property
Dexter
7.0 out of 10, Good, (356 reviews)
Near local attractions like The Heritage House and Keller Veteran Memorial, this welcoming hotel offers complimentary WiFi and parking. Unwind in the seasonal outdoor pool after exploring, with a staff that guests consistently praise for their exceptional service.
$62 nightly
The price is $69
Aug 17 - Aug 18
Total with taxes and fees
Dexter Inn

Comfort Inn Poplar Bluff North

Comfort Inn Poplar Bluff North
2.5 star property
Poplar Bluff
7.8 out of 10, Good, (425 reviews)
Minutes from Poplar Bluff Station, this tranquil hotel offers a 24-hour fitness center and seasonal outdoor pool. Clean rooms provide a restful retreat after exploring nearby North Main Street Historic District and Margaret Harwell Art Museum.
$82 nightly
The price is $92
Aug 9 - Aug 10
Total with taxes and fees
Comfort Inn Poplar Bluff North

OYO Hickory House Inn

OYO Hickory House Inn
2.5 star property
Dexter
5.6 out of 10, (139 reviews)
Cozy rooms with convenient amenities await at this budget-friendly Dexter accommodation. Enjoy complimentary WiFi, free parking, and room service while staying minutes from The Heritage House and Keller Veteran Memorial.
$61 nightly
The price is $67
Jul 19 - Jul 20
Total with taxes and fees
OYO Hickory House Inn

Econo Lodge Dexter

Econo Lodge Dexter
2.0 star property
Dexter
6.8 out of 10, (270 reviews)
This motel offers a cozy overnight stop with easy access to The Heritage House and Dexter Welcome Center. Guests praise the attentive staff who ensure a comfortable stay while enjoying convenient amenities and business-friendly services.
$51 nightly
The price is $57
Aug 16 - Aug 17
Total with taxes and fees
Econo Lodge Dexter

OYO Malden Airport Inn

OYO Malden Airport Inn
2.5 star property
Malden
6.4 out of 10, (78 reviews)
Located in Malden with easy access to Morris State Park, this hotel offers complimentary WiFi and self parking. Room service ensures comfort during your stay, making it an ideal choice for travelers seeking convenience and value.
$59 nightly
The price is $63
Aug 2 - Aug 3
Total with taxes and fees
OYO Malden Airport Inn

Bullwinkles Rustic Lodge

Bullwinkles Rustic Lodge
2.5 star property
Poplar Bluff
8.4 out of 10, Very Good, (213 reviews)
Bullwinkles Rustic Lodge
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Puxico

Puxico is well-known for its attractions such as Mark Twain National Forest and Mingo Wilderness.

A night scene with a clear sky, a crescent moon, and two silhouetted trees against a twilight sky.
Photo by Mike McClain
Open Photo by Mike McClain

Check out reviews of Puxico hotels guests love

Frequently asked questions

How much does a hotel room cost in Puxico?
You can find top hotels in Puxico from $57 with options to suit your budget and needs. If you're looking for an affordable hotel in Puxico that meets all of your requirements, just sort hotels by "Price: low to high" after applying your filters when searching on Hotels.com.
How can I find deals and earn rewards at Puxico hotels?
Discover great deals on Puxico hotel stays with Hotels.com. Take a look at hotel prices mid-week or during the low season as to find those off-peak deals. And make sure to check out our last-minute deals on Puxico hotels.
Can I book Puxico hotels with free cancellation?
To book a refundable Puxico hotel on Hotels.com, just filter hotels by "Property cancellation options" and select "Fully refundable property". Many hotels offer free cancellation, so you can receive a refund if you need to cancel. Some hotels do require cancelling more than 24 hours before check-in, so double-check your booking beforehand.
What hotels do travelers like in Puxico?
Can I book a refundable accommodation in Puxico?
If you want the flexibility to change your travel plans to Puxico, most accommodations provide refundable* bookable rates. You can find these properties by searching our site and using the "fully refundable" filter to narrow down the results.
What will the weather in Puxico be like during my visit?
The warmest months in Puxico are usually July and August with an average temp of 77°F. January and February are the chilliest months when the average temp is 41°F. The rainiest months are April and May.
Why should I book my Puxico hotel through Hotels.com?
There are plenty of reasons to book your Puxico travel with us: our free cancellations on selected hotels gives you the flexibility you're looking for, and with One Keyâ„¢, our rewards program, you will be able to earn and use OneKeyCashâ„¢* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.

Find out more about Puxico

Serenity Awaits: Explore the Enchanting Lakes and Lush Landscapes of Puxico

Discover Puxico, Missouri, a hidden gem nestled in the heart of the Ozarks. This charming town offers a blend of outdoor adventures and small-town hospitality. Explore nearby Lake Wappapello for fishing, boating, and scenic picnicking. Stroll along the picturesque riverside or unwind at the lush landscapes of nearby state parks. Puxico's vibrant community hosts local events and festivals, offering a taste of authentic Midwestern culture. Whether you're seeking tranquility by the lake or a taste of local charm, Puxico is the perfect off-the-beaten-path destination for those craving a unique travel experience.

Discover great hotels in Puxico

Puxico, Missouri offers a range of cozy accommodations, from quaint motels to charming bed-and-breakfasts. Enjoy warm hospitality and a laid-back atmosphere, perfect for unwinding after a day of exploring the scenic beauty and local attractions in this welcoming small town. Here are some of the most popular hotels with our travelers in Puxico:

  1. OYO Hickory House InnOpens in a new window: This charming 2.5-star motel offers a cozy retreat for travelers looking for a pet-friendly experience. With thoughtfully designed accommodations, it provides a welcoming atmosphere for those seeking comfort during their stay. Guests appreciate the convenience of having pets allowed on the property, along with amenities that enhance their experience, such as a warm and inviting ambiance. This property stands out for its focus on providing a relaxing environment, making it an excellent choice for leisure travelers seeking a home away from home.
  2. Dexter InnOpens in a new window: Featuring a 2.5-star rating, Dexter Inn is an inviting hotel that caters to travelers seeking a delightful getaway with their pets. The property boasts stylish rooms and a range of amenities that ensure a comfortable stay. With a pet-friendly policy, guests can enjoy their vacation without leaving their furry companions behind. The hotel's relaxing atmosphere and welcoming service create a memorable experience, perfect for leisure travelers who appreciate a blend of comfort and convenience.
  3. Travelodge by Wyndham DexterOpens in a new window: This 2.0-star hotel is designed with business travelers in mind, offering a refined environment that promotes productivity and comfort. With business amenities including a meeting room and a business center, it provides essential services for those on work-related trips. The property’s sleek design and functional offerings make it an appealing choice for professionals seeking a seamless travel experience. Guests enjoy the convenience and thoughtful details that cater to their specific needs, ensuring a smooth and efficient stay.

Top locations to stay in Puxico

Some of the best areas to stay in when visiting Puxico, Missouri, are Wappapello, Fisk, and Dudley. Wappapello is ideal for families with its recreational activities, while Fisk offers local attractions and a charming atmosphere. Dudley is also appealing, but Wappapello stands out as the best choice for first-time visitors seeking fun and relaxation.

  1. WappapelloOpens in a new window: Wappapello is a fantastic destination for travelers looking to enjoy the great outdoors. Nestled near Wappapello Lake, this area is perfect for families and nature lovers. You can spend your days fishing, boating, or hiking along scenic trails that offer stunning views of the surrounding landscape. The nearby state park also features picnic areas, making it a great spot for a family outing. With its tranquil environment and recreational opportunities, Wappapello is ideal for those seeking a relaxing getaway surrounded by nature.
  2. DudleyOpens in a new window: Dudley is a charming little town that offers a cozy, small-town feel with a strong sense of community. While it may be quieter than nearby areas, Dudley is a great place to unwind and explore local culture. You can enjoy leisurely strolls through the town, meet friendly locals, and discover unique shops that reflect the area's character. It's a lovely spot for travelers who appreciate a slower pace and want to experience authentic Midwestern hospitality.
  3. FiskOpens in a new window: Fisk is another peaceful option for travelers seeking a rural escape. Known for its close-knit community and picturesque surroundings, Fisk allows visitors to immerse themselves in the local lifestyle. The area offers opportunities for outdoor activities such as hiking and birdwatching, making it a great choice for nature enthusiasts. Additionally, the town's unique charm and friendly atmosphere make it an inviting place to relax and enjoy a simpler way of life.

Things to do in Puxico

Puxico offers a delightful blend of outdoor adventures and recreational fun, surrounded by serene lakes, lush forests, and scenic rivers. Visitors can enjoy activities like boating, hiking, or golfing, while also catching exciting events at local arenas. It’s a perfect spot for nature lovers and thrill-seekers alike!

  • The Heritage HouseOpens in a new window – Step back in time at this historic home, where fascinating stories from the past come alive. Discover the unique architecture and rich history that make this site a gem in Puxico.
  • Dexter Welcome Center Depot and MuseumOpens in a new window – Dive into local history at this charming museum. Located in a restored depot, it showcases intriguing exhibits that highlight the region's heritage and culture. Perfect for a leisurely visit as you learn about the area's past.
  • Lake WappapelloOpens in a new window – Enjoy a day at the lake, where you can fish, swim, or simply relax by the water's edge. The picturesque setting offers a perfect backdrop for picnics or a refreshing swim during the warmer months.
  • Lake Wappapello State ParkOpens in a new window – Explore the natural beauty of this national state park, where hiking trails wind through lush landscapes and along the shoreline. Bring your camera to capture stunning views and enjoy a variety of outdoor activities such as camping, boating, or birdwatching.

5 tips for savvy savings when booking a hotel in Puxico

  1. Book for the cheapest times: The most budget-friendly time to visit Puxico is during February, November, and December when hotel prices are lower. For those looking to explore the area's landmarks, history, and culture, staying for at least 2 to 3 days is ideal. This duration allows visitors to appreciate the local attractions, including parks, lakes, historic sites, and state and national parks, all while enjoying great value for their money. During these months, prices may drop, making it an even more appealing time to experience Puxico's rich offerings.
  2. Look for last-minute deals on Hotels.com: To explore last-minute deals to Puxico, visit the DealsOpens in a new window or Last-Minute DealsOpens in a new window section on Hotels.com, where you may discover discounted hotel rates as your travel date approaches. To stay informed about flash sales and special promotions, consider enabling email alerts or push notifications. Additionally, the Smart ShoppingOpens in a new window tool available via the app allows you to compare hotel prices and amenities, making it easier to find the best options. By staying updated on price changes and availability, you could be among the first to book a last-minute getaway.
  3. Be flexible with dates: Hotel prices can fluctuate based on factors like the location, star rating, and time of year, so being flexible with your travel dates could help you save on your stay in a Puxico hotel. If you're seeking something distinctive, boutique hotels often provide a more personalized experience and may offer better value. When you book through Hotels.com, we’ll inform you whether the price for your chosen dates is above or below the average. If the price is on the higher end, we’ll recommend more budget-friendly dates that could help you secure a better deal.
  4. Consider your location: Hotels near the city center usually tend to be more expensive, but thanks to Puxico's great public transportation options, you might discover a more affordable independent hotel a bit farther out that still offers convenient access. For those interested in exploring alternative, less crowded neighborhoods or even nearby cities that aren’t as well-known, there’s often excellent value to be found. Opting for these alternative destinations can provide a more authentic and budget-friendly experience.
  5. Become a Member: Join our membership program for free and start booking your next stay in Puxico! Enjoy exclusive member prices and save on over 100,000 hotels worldwide. As a member, you'll have the opportunity to advance through tiers, unlocking fantastic perks such as complimentary room upgrades (when available) and discounts on food and beverages at select VIP Access properties. Don't miss out on these incredible benefits—sign up today and enhance your travel experience!

Best time to go to Puxico

Puxico experiences its lowest average temperature in January, at 35.8°F (2.1°C), while July is the hottest month, with an average temperature of 79.7°F (26.5°C). April is usually the wettest month. February, April, and June are the peak travel months in Puxico, attracting a higher number of tourists. During this peak period, the weather is mostly sunny, accompanied by light rainfall. On the other hand, January, September, and October tend to be quieter times to visit, marked by light rainfall and mostly sunny conditions.

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