There's a lot visitors like about St. Charles, especially its restaurants and historical sites. Learn about the local heritage of St. Charles at landmarks like Historic Main Street and First Missouri State Capitol Historic Site. You might find that sights like Katy Trail and Lewis & Clark Boathouse and Nature Center are worth a visit.
Hotels in St. Charles
Free cancellation options if plans change
Earn rewards on every night you stay
Save more with Member Prices
Check prices for these dates
Where to stay in St. Charles?

Relax Inn Saint Charles
Relax Inn Saint Charles
6.4 out of 10, (910)
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Go beyond your typical stay in St. Charles
Top neighbourhoods in St. Charles
St. Charles Historic District
St. Charles's St. Charles Historic District neighbourhood is known for its restaurants and bars, and entices visitors with attractions, including Historic Main Street and Missouri River.
Top landmarks in St. Charles

Historic Main Street
You can learn about the history of St. Charles when you stop by Historic Main Street. Visit the shops and top-notch restaurants in this family-friendly area.
Learn more about St. Charles
Explore the restored 1812-era Main Street, lined with charming shops and eateries. Bike the scenic Katy Trail or visit the Ameristar Casino to experience St. Charles' diverse offerings.

Check out reviews of St. Charles hotels guests love

Comfort Suites St Charles - St Louis
10/10 Excellent
Frequently asked questions
Find out more about St. Charles
Find out more about St. Charles
Keep exploring
Keep exploring
- Neighbourhoods
- Landmarks
- Star Rating
- Accommodation Types
- Facilities
- Hotels close to nearby airports
- Nearby cities
- Top Cities in United States of America
- More Hotels
- Hotels near Ameristar Casino St. Charles
- Hotels near Historic Main Street
- Hotels near St Charles Convention Center
- Hotels near Lindenwood University
- Hotels near Family Arena
- Hotels near Fast Lane Classic Cars
- Hotels near Katy Trail
- Hotels near Lewis & Clark Boathouse and Nature Center
- Hotels near Missouri Bluffs Golf Course
- Hotels near First Missouri State Capitol Historic Site
- Hotels near SSM Health St. Joseph Hospital
- Hotels near Weldon Spring Site Interpretive Center
- Hotels near Lewis and Clark Trail Trailhead
- Hotels near Jaycee Park
- Hotels with Parking in St. Charles
- Business Hotels in St. Charles
- Family Hotels in St. Charles
- Hotels with a Pool in St. Charles
- Hotels with Free Breakfast in St. Charles
- Hotels with a Gym in St. Charles
- Cheap Hotels in St. Charles
- Pet-Friendly Hotels in St. Charles
- Hotels with Kitchens in St. Charles
- Las Vegas Hotels
- New York Hotels
- Orlando Hotels
- Myrtle Beach Hotels
- Chicago Hotels
- San Diego Hotels
- Panama City Beach Hotels
- Destin Hotels
- Los Angeles Hotels
- Ocean City Hotels
- Miami Hotels
- Gulf Shores Hotels
- Boston Hotels
- Nashville Hotels
- Pigeon Forge Hotels
- San Francisco Hotels
- Atlanta Hotels
- Houston Hotels
- Virginia Beach Hotels
- Atlantic City Hotels
- Casino Queen Hotel
- St. Louis Union Station Hotel, Curio Collection by Hilton
- Wingate by Wyndham St. Louis/Fenton Route 66
- Hilton St. Louis Airport
- Forest Park Hotel by MDR
- The Cheshire
- Wingate by Wyndham St. Louis Airport
- The Wildwood Hotel
- Comfort Inn & Suites
- Drury Inn & Suites St. Louis Union Station
- Renaissance St. Louis Airport Hotel
- Larkspur Landing Extended Stay Suites St. Louis Riverport - Airport West
- Marriott St. Louis Grand
- Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
- Hampton Inn St. Louis-Downtown (At the Gateway Arch)
- Embassy Suites by Hilton St. Louis Downtown
- River City Casino & Hotel
- Live by Loews - St.Louis
- Motel 6 Hazelwood, MO
- The Royal Sonesta Chase Park Plaza St. Louis
- Hilton Pennywell St. Louis at the Arch
- Home2 Suites by Hilton St. Louis Downtown
- Courtyard by Marriott St Louis Westport Plaza
- Best Western St. Louis-Kirkwood Route 66
- The West End
- Best Western St. Louis Inn
- AC Hotel St. Louis Clayton
- La Quinta Inn by Wyndham St. Louis Hazelwood - Airport North
- Best Western Plus St. Louis West-Westport
- Elimwood Hotel, A Ramada by Wyndham
- Angad Arts Hotel St. Louis, Tapestry Collection by Hilton
- Hilton St. Louis Frontenac
- Americas Best Value Inn St. Louis South
- Pear Tree Inn St. Louis Convention Center
- Best Western Plus St. Louis Airport Hotel
- Le Méridien St. Louis Clayton
- Drury Inn & Suites St. Louis Airport
- Marriott St. Louis Airport
- Best Western Plus Pontoon Beach
- DoubleTree by Hilton St. Louis Forest Park
- Drury Inn & Suites St. Louis Brentwood
- Fairfield Inn & Suites by Marriott St. Louis Downtown
- Drury Inn & Suites St. Louis Forest Park
- Best Western St. Louis Airport North Hotel & Suites
- The Westin St. Louis
- DoubleTree by Hilton St. Louis Airport
- Hampton Inn & Suites St. Louis at Forest Park
- Residence Inn by Marriott St Louis Downtown
- HoteLumiere at the Arch
- Four Seasons Hotel St Louis