Hotels in Matthews

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Check prices for these dates

Tonight
May 6 - May 7
Tomorrow
May 7 - May 8
This weekend
May 9 - May 11
Next weekend
May 16 - May 18

Where to stay in Matthews?

TownePlace Suites by Marriott Sikeston
Suite, 1 Bedroom

TownePlace Suites by Marriott Sikeston

3.0 star property
4.0 out of 10, (1)
The price is $162
includes taxes & fees
$143 per night
May 13 - May 14
TownePlace Suites by Marriott Sikeston
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Matthews

The region around Matthews is home to attractions such as Sikeston Depot Museum and The Book Bug.

See all hotels in Matthews
A tranquil hotel pool encircled by beautiful arches, enhancing the ambiance for leisure and relaxation.

Summer Getaway Sale

Save 25% or more on select hotels, and earn 50% more rewards on all properties. Book by May 26 and travel by Sep 30, 2025. See terms*
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Frequently asked questions

What hotels do travelers like in Matthews?
Guests like Pear Tree Inn Sikeston, Best Western Plus Sikeston and Drury Inn & Suites Sikeston, MO.
Can I book refundable accommodations in Matthews?
If you’re looking for the flexibility to change your plans to Matthews, most hotels offer refundable* bookable rates. You can find these properties by searching our site and using the “fully refundable” filter to narrow the results down.
What will the weather in Matthews be like during my vacation?
July and August are typically the warmest months in Matthews when the average temp is 77°F. January and February are the coldest months when the average temperature is 41°F. April and March are the months with the most rain.
Why should I book my Matthews accommodation with Hotels.com?
There are lots of reasons to book your Matthews trip with us: our free cancellations on selected hotels* gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™** on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.

Terms and conditions

*Book by 5/26/2025 11:59 pm in hotel property local time. Stay between 4/17/2025-9/30/2025. Member Prices are available to Hotels.com® app users and One Key members. Limited availability, blackout periods may apply.

OneKeyCash is not redeemable for cash and can only be used on Hotels.com®, Expedia®, and Vrbo®.

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