Hotels in Matthews

Free cancellation options if plans change

Unlock travel rewards with One Key

Save more with Member Prices

Check prices for these dates

Tonight

Aug 10 - Aug 11

Tomorrow

Aug 11 - Aug 12

This weekend

Aug 14 - Aug 16

Next weekend

Aug 21 - Aug 23

Where to stay in Matthews?

Properties are selected based on real traveler reviews and popularity among guests who’ve booked a night in Matthews on Hotels.com. These Matthews hotels consistently deliver on comfort, location and traveler experience. Last updated on August 10, 2026.

Indoor pool, outdoor pool

Drury Inn & Suites Sikeston, MO

Sikeston

$111 nightly

Aug 15 - Aug 16

Total with taxes and fees

Exterior

Hampton Inn Sikeston

Sikeston

$98 nightly

Aug 27 - Aug 28

Total with taxes and fees

Free daily full breakfast

Best Western Plus Sikeston I-55

Sikeston

$95 nightly

Aug 16 - Aug 17

Total with taxes and fees

1 bedroom, desk, laptop workspace, blackout drapes

Days Inn and Suites by Wyndham Sikeston

Sikeston

$65 nightly

Sep 9 - Sep 10

Total with taxes and fees

Property amenity

Fairfield Inn & Suites by Marriott Sikeston

Sikeston

$110 nightly

Aug 16 - Aug 17

Total with taxes and fees

Desk, blackout drapes, iron/ironing board (on request), WiFi (free)

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

Sikeston

$67 nightly

Aug 16 - Aug 17

Total with taxes and fees

Exterior

Holiday Inn Express & Suites Sikeston Southwest by IHG

Sikeston

$97 nightly

Aug 23 - Aug 24

Total with taxes and fees

Room, 1 King Bed, Accessible, Non Smoking | Desk, laptop workspace, blackout drapes, WiFi (free)

Super 8 by Wyndham Sikeston/Miner Area

Sikeston

$63 nightly

Aug 11 - Aug 12

Total with taxes and fees

Property amenity

TownePlace Suites by Marriott Sikeston

Sikeston

$109 nightly

Aug 16 - Aug 17

Total with taxes and fees

Lobby

Hampton Inn By Hilton Dexter

Dexter

$98 nightly

Aug 16 - Aug 17

Total with taxes and fees

Exterior

Comfort Inn & Suites Sikeston I-55

Sikeston

$95 nightly

Aug 30 - Aug 31

Total with taxes and fees

Standard Room, 2 Double Beds, Non Smoking | Blackout drapes, iron/ironing board (on request), WiFi (free)

Reelfoot Lake Inn

Tiptonville

$65 nightly

Aug 25 - Aug 26

Total with taxes and fees

Iron/ironing board (on request), WiFi (free), bed sheets

Country Yard Inn and Suite

Sikeston

$59 nightly

Sep 4 - Sep 5

Total with taxes and fees

Breakfast, lunch and dinner served

Travelodge by Wyndham Dexter

Dexter

$91 nightly

Aug 23 - Aug 24

Total with taxes and fees

Laptop workspace, blackout drapes, cribs (free), WiFi (free)

Super 8 by Wyndham Charleston/Sikeston East MO

Charleston

$56 nightly

Sep 8 - Sep 9

Total with taxes and fees

Breakfast area

Dexter Inn

Dexter

$61 nightly

Aug 13 - Aug 14

Total with taxes and fees

Room, 1 Queen Bed, Non Smoking | Desk, laptop workspace, blackout drapes, WiFi (free)

Super 8 By Wyndham Marston

Marston

$73 nightly

Aug 16 - Aug 17

Total with taxes and fees

Exterior

The Riverstone Hotel Charleston-Sikeston

Charleston

$66 nightly

Sep 7 - Sep 8

Total with taxes and fees

View all properties

Go beyond your typical stay in Matthews

Pet friendly

Pool

Check out reviews of Matthews hotels guests love

Hampton Inn Sikeston

Hampton Inn Sikeston

8/10 Good

"Hotel was nice but unfortunately someone decided to smoke in the elevator one night which made it shut down. So, until the repair was completed, everyone one the upper floors had to take the stairs down multiple floors. Usually not that big of an issue, but we were there for a bike ride and had to carry our bikes down three floors in the morning. Thankfully the elevator was fixed by the time we got back. Not really anything the hotel or staff caused, but just repercussions from the act of one person doing something stupid! We will definitely stay here again"

Holiday Inn Express & Suites Sikeston Southwest by IHG

Holiday Inn Express & Suites Sikeston Southwest by IHG

8/10 Good

"Staff was super nice, giving us more than plenty towels upon request as I mentioned reviews found the suite was only equipped with towels for 2. A convenient and cozy place to stay for a night. Adequate hot breakfast. Gym is small with only bikes, treadmills and weights. The A/C on the wall in the gym was dripping hard. Our room was near the elevator and the wall seemed to be as thin as cardboard as I could hear every sound throughout the night. Bed mattress too soft for me."

Days Inn and Suites by Wyndham Sikeston

Days Inn and Suites by Wyndham Sikeston

10/10 Excellent

"Was a very clean, quiet place to stay. My only complaint was the breakfast was disappointing. They only offered cereal or waffles. Being diabetic I couldn't have either 😥. Yogurt, fruit, eggs/bacon/sausage would be good options. The staff was very nice and helpful."

Hampton Inn By Hilton Dexter

Hampton Inn By Hilton Dexter

10/10 Excellent

"During summer time, don’t park behind the building. There’s a pond in the distance and the light draws a TON of mosquitoes there, but the other entrances are all fine. The pond makes for a beautiful view with ducks and cranes, though. Everything about the bed was heavenly. Send the whole thing to my house, pronto! LOL The supplied shower body gel, shampoo, conditioner, and body lotion by Zero% is to die for! Smells great, super moisturizing, and good for the planet? Wow! The free breakfast was awesome! Waffles and fresh oatmeal with a HUGE variety of toppings, cereal and milk, juices, coffees and teas with sweeteners, sugars, creams, and real honey, cocoa, yogurt, boiled eggs, scrambled eggs, bacon, sausage, ranch potatoes, bagels (soft!), muffins, scones, toast and all the spreads for them, fresh fruit… what more could you need FOR FREE? Love love love the packaged reusable/disposable coffee pod holder for the coffee maker in the room. No more worrying if it was cleaned, cleaned properly, or used to wash someone’s underwear beforehand. Water pressure, shower head, and temperature was just right. I wish the light would stay on during the shower, though. And even with the door barely ajar the light and fan was still kicking on when I wasn’t in the bathroom. I was in the bed. Alone. Air conditioner/heater is a vast improvement from the old style in other hotels. It has a wall control just like home! The TV is giant! Anyway, will absolutely be back more than once. Thank you!"

Frequently asked questions

How much does a hotel room cost in Matthews?

You can discover great hotels in Matthews from $57 with properties to suit all budgets and needs. If you're looking for an affordable hotel in Matthews that meets all of your requirements, just sort hotels by "Price: low to high" after applying your filters when searching on Hotels.com.

How can I find deals and earn rewards at Matthews hotels?

Discover great deals on Matthews hotel stays with Hotels.com. Take a look at hotel prices mid-week or during the low season as to find those off-peak deals. And make sure to check out our last-minute deals on Matthews hotels.

Can I book Matthews hotels with free cancellation?

In order to book a refundable Matthews hotel, simply filter hotels by "Property cancellation options" and select "Fully refundable property". Most hotels offer free cancellation, so you can receive a refund if you need to cancel. Some hotels do require cancelling more than 24 hours before check-in, so double-check your booking beforehand.

What hotels do travelers like in Matthews?

Guests like Drury Inn & Suites Sikeston, MO, Days Inn and Suites by Wyndham Sikeston and Holiday Inn Express & Suites Sikeston Southwest by IHG.

Can I book refundable accommodations in Matthews?

If you're looking for the flexibility to change your plans to Matthews, most hotels offer refundable* bookable rates. You can find these properties by searching our site and using the "fully refundable" filter to narrow the results down.

What will the weather in Matthews be like during my vacation?

July and August are typically the warmest months in Matthews when the average temp is 77°F. January and February are the coldest months when the average temperature is 41°F. April and March are the months with the most rain.

Why should I book my Matthews accommodation with Hotels.com?

There are lots of reasons to book your Matthews trip with us: our free cancellations on selected hotels gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.

Keep exploring

f1c976fd-6d1f-4805-8219-46f17988e350aa4c5bd1-4273-4480-b917-fac6aef9b91f