Skip to main content.

Hotels in Commerce, Missouri

Search & Compare Commerce Hotels

Save more with Secret Prices

Get instant savings with Secret Prices

  • Pay now or later on most rooms
  • Free cancellation on most rooms
  • Price Guarantee

Best hotels in Commerce

What's Commerce Like?

If you're looking to discover somewhere new, look no further than Commerce. Whether you're planning to stay for a night or for the week, the area around Commerce has accommodations to fit every need. Search for hotels in Commerce with by checking our online map. Our map displays the areas and neighborhoods around all Commerce hotels so you can see how close you are from landmarks and attractions, and then refine your search within the larger area. The best Commerce hotel deals are here with our lowest price guarantee.

How to Get to Commerce

Flights to Commerce

  • • Cape Girardeau, MO (CGI-Cape Girardeau Municipal), 8 mi (12.9 km) from central Commerce
  • • Cairo, IL (CIR-Cairo Regional), 14 mi (22.5 km) from central Commerce