Hotels in East Prairie

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Where to stay in East Prairie?

Properties are selected based on real traveler reviews and popularity among guests who’ve booked a night in East Prairie on Hotels.com. These East Prairie hotels consistently deliver on quality, location and traveler experience. Last updated on .

Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO
3.0 star property
Sikeston
9.6 out of 10, Exceptional, (1,007 reviews)
Escape to this serene Sikeston hotel with both indoor and outdoor pools near restaurants and shopping. The fitness center, free breakfast, WiFi and parking enhance your stay, while the helpful staff ensures comfort just minutes from Central Park.
$94 nightly
The price is $108
Sep 13 - Sep 14
Total with taxes and fees
Drury Inn & Suites Sikeston, MO

Hampton Inn Sikeston

Hampton Inn Sikeston
2.5 star property
Sikeston
9.0 out of 10, Wonderful, (620 reviews)
Dive into vacation mode at this welcoming hotel with an indoor pool and fitness center near Central Park. After enjoying the complimentary breakfast, explore Sikeston Depot Museum before returning to relax in modern rooms with free WiFi.
$102 nightly
The price is $115
Sep 20 - Sep 21
Total with taxes and fees
Hampton Inn Sikeston

Sleep Inn at Discovery Park of America

Sleep Inn at Discovery Park of America
2.5 star property
Union City
9.2 out of 10, Wonderful, (430 reviews)
Slip into this inviting Union City hotel just minutes from Discovery Park of America's interactive exhibits. After exploring nearby attractions, unwind in the refreshing indoor pool or maintain your routine in the 24-hour fitness center. Free breakfast, WiFi and parking enhance your value-packed stay.
$87 nightly
The price is $104
Sep 28 - Sep 29
Total with taxes and fees
Sleep Inn at Discovery Park of America

Best Western Plus Sikeston I-55

Best Western Plus Sikeston I-55
2.5 star property
Sikeston
8.4 out of 10, Very Good, (1,009 reviews)
Experience comfort at this Sikeston hotel, offering free breakfast and parking close to Central Park. The helpful staff welcomes guests to enjoy the indoor pool and fitness center. With easy access to Sikeston Depot Museum, you'll find everything needed for a convenient Missouri stay.
$87 nightly
The price is $99
Sep 20 - Sep 21
Total with taxes and fees
Best Western Plus Sikeston I-55

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
2.5 star property
Sikeston
8.4 out of 10, Very Good, (820 reviews)
This peaceful hotel offers a complimentary continental breakfast, free WiFi, and convenient parking. Located near I-55 Exit 67, guests consistently praise the helpful staff and clean rooms that provide a quiet retreat after exploring local attractions.
$57 nightly
The price is $64
Sep 13 - Sep 14
Total with taxes and fees
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

Days Inn and Suites by Wyndham Sikeston

Days Inn and Suites by Wyndham Sikeston
2.0 star property
Sikeston
7.2 out of 10, Good, (1,004 reviews)
Travelers rave about this serene retreat with helpful staff and clean rooms. Take advantage of free WiFi, parking, and on-the-go breakfast. Work out in the fitness center before exploring Central Park and Sikeston Depot Museum nearby.
$66 nightly
The price is $76
Sep 10 - Sep 11
Total with taxes and fees
Days Inn and Suites by Wyndham Sikeston

The Riverstone Hotel Charleston-Sikeston

The Riverstone Hotel Charleston-Sikeston
2.5 star property
Charleston
6.8 out of 10, (431 reviews)
$66 nightly
The price is $74
Sep 10 - Sep 11
Total with taxes and fees
The Riverstone Hotel Charleston-Sikeston

Reelfoot Lake Inn

Reelfoot Lake Inn
2.0 star property
Tiptonville
7.2 out of 10, Good, (504 reviews)
$55 nightly
The price is $63
Oct 8 - Oct 9
Total with taxes and fees
Reelfoot Lake Inn

Fairfield Inn & Suites by Marriott Sikeston

Fairfield Inn & Suites by Marriott Sikeston
3.0 star property
Sikeston
9.4 out of 10, Exceptional, (108 reviews)
Located in Sikeston, this hotel offers free breakfast, WiFi, and parking. Take a refreshing swim in the indoor pool or grab a bite at the restaurant. Nearby attractions include Central Park and Sikeston Depot Museum for local exploration.
$101 nightly
The price is $114
Sep 17 - Sep 18
Total with taxes and fees
Fairfield Inn & Suites by Marriott Sikeston

Holiday Inn Express & Suites Sikeston Southwest by IHG

Holiday Inn Express & Suites Sikeston Southwest by IHG
2.5 star property
Sikeston
8.8 out of 10, Excellent, (507 reviews)
Experience Sikeston from this hotel with free breakfast, WiFi, and parking. Take a morning dip in the indoor pool or hit the fitness center. Near Central Park and Sikeston Depot Museum, guests love the helpful staff and clean rooms.
$106 nightly
The price is $120
Oct 9 - Oct 10
Total with taxes and fees
Holiday Inn Express & Suites Sikeston Southwest by IHG

Holiday Inn Express & Suites Union City by IHG

Holiday Inn Express & Suites Union City by IHG
2.5 star property
Union City
9.4 out of 10, Exceptional, (348 reviews)
Relax in this Union City hotel where the 24-hour fitness center keeps you energized. Free breakfast, WiFi, and parking await near Discovery Park of America. After exploring nearby attractions, return to rooms praised by guests for comfort and service.
$110 nightly
The price is $131
Sep 20 - Sep 21
Total with taxes and fees
Holiday Inn Express & Suites Union City by IHG

Super 8 by Wyndham Sikeston/Miner Area

Super 8 by Wyndham Sikeston/Miner Area
2.0 star property
Sikeston
7.0 out of 10, Good, (672 reviews)
Cozy lodging near Central Park and Sikeston Depot Museum with complimentary breakfast, WiFi, and parking. Just 29 minutes from Cape Girardeau Municipal Airport, this Super 8 offers comfortable accommodations for exploring the area.
$57 nightly
The price is $65
Sep 14 - Sep 15
Total with taxes and fees
Super 8 by Wyndham Sikeston/Miner Area

Quality Inn Union City US 51

Quality Inn Union City US 51
2.5 star property
Union City
8.2 out of 10, Very Good, (545 reviews)
This Quality Inn offers a seasonal outdoor pool, rejuvenating hot tub, and complimentary breakfast near County Market Place. With free WiFi, parking, and easy access to Reelfoot Shopping Center, travelers appreciate the attentive staff.
$67 nightly
The price is $80
Oct 4 - Oct 5
Total with taxes and fees
Quality Inn Union City US 51

Hampton Inn Union City

Hampton Inn Union City
2.5 star property
Union City
9.6 out of 10, Exceptional, (192 reviews)
Minutes from County Market Place, this hotel offers a welcoming indoor pool, fitness center, and free breakfast. Guests rave about the helpful staff, while free parking makes exploring easy. Reelfoot Shopping Center is nearby for retail therapy.
$102 nightly
The price is $121
Sep 20 - Sep 21
Total with taxes and fees
Hampton Inn Union City

Super 8 by Wyndham Charleston/Sikeston East MO

Super 8 by Wyndham Charleston/Sikeston East MO
2.0 star property
Charleston
6.8 out of 10, (665 reviews)
This Charleston motel offers complimentary WiFi, parking, and on-the-go breakfast daily. Located with convenient interstate access to Cape Girardeau, guests consistently praise the helpful staff. The comfortable accommodations provide a practical base for exploring southeastern Missouri.
$60 nightly
The price is $66
Sep 9 - Sep 10
Total with taxes and fees
Super 8 by Wyndham Charleston/Sikeston East MO

TownePlace Suites by Marriott Sikeston

TownePlace Suites by Marriott Sikeston
3.0 star property
Sikeston
9.4 out of 10, Exceptional, (23 reviews)
$118 nightly
The price is $134
Sep 17 - Sep 18
Total with taxes and fees
TownePlace Suites by Marriott Sikeston

Country Hearth Inn & Suites Union City

Country Hearth Inn & Suites Union City
2.5 star property
Union City
8.6 out of 10, Excellent, (576 reviews)
Inviting comfort awaits at this Union City motel where complimentary continental breakfast starts your day. Located near County Market Place and Reelfoot Shopping Center, enjoy free WiFi and parking with attentive staff ready to assist you.
$66 nightly
The price is $79
Oct 8 - Oct 9
Total with taxes and fees
Country Hearth Inn & Suites Union City

Hospitality House Union City I 69 / US 51

Hospitality House Union City I 69 / US 51
2.5 star property
Union City
6.8 out of 10, (402 reviews)
Discover this Union City hotel offering a seasonal outdoor pool and onsite restaurant. Free breakfast, WiFi, and parking add convenience. Visitors appreciate the helpful staff and proximity to County Market Place and Reelfoot Shopping Center.
$56 nightly
The price is $66
Sep 9 - Sep 10
Total with taxes and fees
Hospitality House Union City I 69 / US 51

MainStay Suites at Discovery Park of America

MainStay Suites at Discovery Park of America
2.5 star property
Union City
8.8 out of 10, Excellent, (47 reviews)
Explore Union City from this welcoming hotel with 24-hour fitness amenities and convenient hiking trails in the area. Near Kiwanis Park and Masquerade Theatre, you'll enjoy free breakfast, WiFi, and parking while rooms offer refrigerators and microwaves.
$110 nightly
The price is $130
Sep 21 - Sep 22
Total with taxes and fees
MainStay Suites at Discovery Park of America
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top landmarks in East Prairie

Learn more about East Prairie

East Prairie is well-known for its attractions such as Big Oak Tree State Park and Mississippi River.

A tree-lined landscape with a river and fields.

Check out reviews of East Prairie hotels guests love

Frequently asked questions

How much does a hotel room cost in East Prairie?
You can choose a great hotel in East Prairie from $63 with properties to suit all budgets and needs. To find an affordable hotel in East Prairie that meets all of your requirements, just apply filters on Hotels.com and sort hotels by "Price: low to high".
How can I find deals and earn rewards at East Prairie hotels?
Discover great deals on East Prairie hotel stays with Hotels.com. Take a look at hotel prices mid-week or during the low season as to find those off-peak deals. If you're up for a spontaneous trip, don't forget to check out our last-minute deals on East Prairie hotels.
Can I book East Prairie hotels with free cancellation?
It's easy to book a refundable East Prairie hotel on Hotels.com. Simply filter hotels by "Property cancellation options" and select "Fully refundable property". Most hotels offer free cancellation, so you can receive a refund if you need to cancel. Some hotels do require cancelling more than 24 hours before check-in, so double-check your booking beforehand.
What hotels do travelers like in East Prairie?
Can I book a refundable hotel in East Prairie?
If you need the flexibility to change your travel plans to East Prairie, most hotels provide refundable* rates you can book. You can find these properties by searching our site and using the "fully refundable" filter to narrow the results down.
What will the weather in East Prairie be like during my trip?
July and August are typically the warmest months in East Prairie when the average temp is 77°F. January and February are the coldest months when the average temperature is 41°F. March and April are the months with the most rain.
Why should I book my East Prairie accommodation with Hotels.com?
There are lots of reasons to book your East Prairie trip with us: our free cancellations on selected hotels gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.

Find out more about East Prairie

Whispers of Nature: Discover the Hidden Treasures of East Prairie

Discover East Prairie, Missouri, a hidden gem that perfectly blends charming small-town allure with nature's tranquility. Nestled near stunning lakes and expansive state parks, this inviting destination is perfect for outdoor enthusiasts, offering fishing, hiking, and birdwatching opportunities. Stroll through urban parks or unwind at comfortable hotels and vacation rentals that promise friendly hospitality. East Prairie also hosts events that showcase local culture and community spirit, making it an ideal spot for a unique getaway. Experience the warmth of Missouri hospitality in this picturesque town where adventure and relaxation await.

Discover great hotels near East Prairie

East Prairie, Missouri offers a range of hotel accommodations, from cozy motels to vacation rentals, ensuring a comfortable stay for travelers. Room rates are generally affordable, and you can find some great deals among the local hotels, making it easy to enjoy your trip without breaking the bank. Here are some of the most popular hotels with our travelers near East Prairie:

  1. The Riverstone HotelOpens in a new window: This inviting budget-friendly hotel is ideal for leisure travelers seeking comfort and a welcoming atmosphere. With a focus on providing a cozy retreat, this hotel features key amenities such as pet-friendly accommodations and a pleasant environment that makes for a relaxing stay. Guests appreciate the cleanliness of the rooms, which stand out in this price range, contributing to an overall enjoyable experience.
  2. Super 8 by Wyndham Charleston/Sikeston East MOOpens in a new window: Perfect for those traveling with family, Super 8 by Wyndham Charleston/Sikeston East MO is a charming budget-friendly motel that emphasizes a family-oriented experience. It offers amenities designed to enhance comfort for parents and children alike, including complimentary cribs for younger guests. The inviting atmosphere ensures a memorable stay, and visitors have enjoyed the overall experience, highlighting the pleasant environment.
  3. Eagle Inn CharlestonOpens in a new window: This budget-friendly motel is an excellent choice for travelers seeking a pet-friendly experience. With comfortable accommodations and a focus on providing a welcoming atmosphere, Eagle Inn Charleston caters to those who enjoy traveling with their furry companions. The property offers a range of pet amenities, creating a delightful experience for pet owners.

Where to stay near East Prairie

When visiting East Prairie, Missouri, some great areas to stay in are Charleston, Miner, and Matthews. Charleston offers a charming small-town atmosphere, while Miner is known for its delightful dining options and cozy cafes. Matthews provides unique local attractions. For first-time visitors, Miner is best suited due to its friendly atmosphere and variety of dining experiences.

  1. CharlestonOpens in a new window: Charleston is a charming small town that offers a cozy stay with a delightful mix of history and local culture. Visitors can explore its quaint downtown area filled with unique shops and friendly cafes, perfect for a leisurely day of browsing and dining. The town's rich history is showcased through its well-preserved architecture and local museums, making it an engaging spot for history buffs. Additionally, Charleston hosts various community events throughout the year, bringing a lively atmosphere to the town.
  2. MinerOpens in a new window: If you’re looking for a place with easy access to dining and cafes, Miner is a great choice. This friendly community provides a variety of casual eateries and coffee shops that are perfect for grabbing a bite or relaxing with a warm drink. The proximity to nearby shopping areas adds to Miner’s appeal, allowing travelers to enjoy local boutiques and larger retail options. It’s a convenient base for exploring the surrounding attractions while enjoying the comforts of home.
  3. MatthewsOpens in a new window: Matthews is a peaceful destination that offers a more laid-back experience in the heart of Missouri. The town is surrounded by beautiful landscapes, making it ideal for a quiet getaway. While it’s smaller and less bustling, Matthews features local parks and recreational areas where visitors can unwind and enjoy nature. Plus, its close-knit community vibe provides a warm welcome, making it a great spot to relax away from the busier tourist areas.

Things to do in and around East Prairie

East Prairie is a delightful destination for outdoor enthusiasts and leisure seekers alike. With stunning lakes, lush forests, and expansive parks, you'll find endless opportunities for boating, hiking, and golfing. Enjoy leisurely strolls through vibrant urban parks or relax at dog-friendly spots. Plus, vacation rentals offer a cozy base to explore this charming area!

  • Columbus-Belmont State ParkOpens in a new window – Discover the beauty of this national state park where you can enjoy scenic views of the Mississippi River. Bring your family for a day of picnicking, hiking along the trails, or simply relaxing by the lakeside. This park is an excellent spot for outdoor enthusiasts looking to connect with nature.
  • New Madrid Historical MuseumOpens in a new window – Dive into the rich history of the New Madrid earthquakes at this enlightening museum. Explore exhibits that showcase artifacts and stories from the past, allowing you to grasp the impact of these significant events on the region. It's a must-visit for anyone curious about local history.
  • Hunter-Dawson State Historic SiteOpens in a new window – Step back in time at this historic house which beautifully reflects the architecture and lifestyle of the 19th century. Take a guided tour to learn about the lives of the Dawson family and the historical significance of their home, set in a picturesque landscape.
  • Marston Community CenterOpens in a new window – Engage with the local community at this vibrant arts center. Participate in workshops, attend events, or simply enjoy the lively atmosphere. It's a great spot to meet locals and get a taste of community life.
  • Front Street Studio & Art GalleryOpens in a new window – Explore the creativity on display at this charming art gallery. Admire local artwork and perhaps find a unique piece to take home. The gallery often hosts events and exhibitions, making it a hub for artistic expression in the area.

4 tips for savvy savings when booking a hotel in East Prairie

  1. Book for the cheapest times: The most budget-friendly time to visit East Prairie is during January, February, and December, when hotel prices are lower. A stay of at least 1 to 2 days is perfect for discovering the area's rich history and culture. Visitors can explore significant landmarks such as a historic fort, a modern civic government building, and a history museum. Additionally, enjoy the natural beauty at local parks, hiking trails, and recreation areas, all offering great value for money. With these affordable options, travelers can experience the charm of East Prairie without overspending.
  2. Look for last-minute deals on Hotels.com: To explore last-minute options in East Prairie, consider checking the DealsOpens in a new window and Last-Minute DealsOpens in a new window sections on Hotels.com, where you may discover discounted rates as your travel date approaches. By enabling email alerts or push notifications, you could stay updated on flash sales and special promotions. Additionally, Smart ShoppingOpens in a new window is a handy comparison tool available through the app, allowing you to compare hotel prices and amenities effectively. This way, if prices drop or new rooms become available, you might be among the first to know, helping you secure our best options for your getaway.
  3. Be flexible with dates: Prices can fluctuate based on factors like the hotel's location, star rating, and the time of year, so being flexible with your travel dates may help you find a better deal on your stay in an East Prairie hotel. If you're interested in unique accommodations, boutique hotels often provide a more personalized experience and can sometimes offer better value. When you book through Hotels.com, we’ll inform you if the price for your chosen dates is above or below the average. If the price leans toward the higher end, we’ll suggest alternative dates that could be more budget-friendly to help you explore your options.
  4. Consider your location: Staying near popular attractions or city centers can be convenient, but it often comes with higher prices. For more budget-friendly options, you might want to look at hotels in less central areas or neighborhoods, striking a balance between cost and accessibility to the sites you wish to visit. Independent hotels located a bit further out are usually more likely to be affordable and can offer a more authentic experience.

Best time to go to East Prairie

East Prairie experiences its lowest average temperature in January, at 36.3°F (2.4°C), while July is the hottest month, with an average temperature of 79.5°F (26.4°C). March is usually the wettest month. January, June, and July are the peak travel months in East Prairie, attracting a higher number of tourists. During this peak period, the weather is mostly sunny, accompanied by light rainfall. On the other hand, October to December tend to be quieter times to visit, marked by light rainfall and mostly sunny conditions.

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