If you're looking to discover somewhere new, look no further than Effingham. Whether you're planning to stay for a night or for the week, the area around Effingham has accommodations to fit every need. Search for hotels in Effingham with Hotels.com by checking our online map. Our map displays the areas and neighborhoods around all Effingham hotels so you can see how close you are from landmarks and attractions, and then refine your search within the larger area. The best Effingham hotel deals are here with our lowest price guarantee.
Hotels in Effingham
Free cancellation options if plans change
Unlock travel rewards with One Key
Save more with Member Prices
Check prices for these dates
Where to stay in Effingham?
Create new moments at Effingham hotels

Hyatt Place Florence Downtown
Hyatt Place Florence Downtown
8.8 out of 10, Excellent, (1004)
$97 nightly
The price is $109
Sep 8 - Sep 9
Total with taxes and fees
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Go beyond your typical stay in Effingham
Pet friendly
Check out reviews of Effingham hotels guests love
Frequently asked questions
Find out more about Effingham
Find out more about Effingham
Keep exploring
Keep exploring
- Galivants Ferry Hotels
- Gresham Hotels
- Hemingway Hotels
- Johnsonville Hotels
- Scranton Hotels
- Mayesville Hotels
- Lynchburg Hotels
- Olanta Hotels
- Berrys Crossroads Hotels
- Hotels near Ronald E. McNair Life History Center
- Hotels near Lynches Lake Historical Society
- Hotels near The Bean Market
- Hotels near The Country Club at Lake City
- Hotels near Lions Park
- Nesmith Hotels
- Pamplico Hotels
- Sellers Hotels
- Hotels near Fryar's Topiary Garden
- Hotels near Sumter National Golf Club
- Hotels near Oakdale Country Club
- Hotels near Beaver Creek Golf Club
- Hotels near Kalmia Gardens
- Hotels near Florence National Cemetery
- Hotels near Columns Plantation
- Aynor Hotels
- Blenheim Hotels
- Cades Hotels
- Centenary Hotels
- Coward Hotels
- Hotels near Hartsville Regional
- Stuckey Hotels
- Lamar Hotels
- Quinby Hotels
- Shiloh Hotels
- North Hartsville Hotels
- Society Hill Hotels
- Oswego Hotels
- Cartersville Hotels
- Fork Hotels
- Ashland Hotels
- Peedee Hotels
- Hotels near Palmetto Shores Lake
- Brittons Neck Hotels
- Hotels near Carolinas Hospital System Marion
- Hotels near Florence Veterans Park
- Hotels near Pee Dee Mental Health Center
- Darlington Hotels
- Gable Hotels
- Lake City Hotels
- Timmonsville Hotels
- North Myrtle Beach Hotels
- Hartsville Hotels
- Conway Hotels
- Mullins Hotels
- Kingstree Hotels
- Turbeville Hotels
- Dillon Hotels
- Marion Hotels
- Bishopville Hotels
- Latta Hotels
- Hotels near Darlington Raceway
- Charleston Hotels
- Columbia Hotels
- Hotels with a Pool in Florence
- Hotels with Parking in Florence
- Hotels with a Fitness Center in Florence
- Hotels with Free Breakfast in Florence
- Hotels with Kitchens in Florence
- Pet Friendly Hotels in Florence
- Motels in Florence
- Cheap Hotels in Florence
- 2 Star Hotels in Florence
- 3 Star Hotels in Florence
- Business Hotels in Florence
- LGBTQIA-Welcoming Hotels in Florence
- Family Hotels in Florence
- Florence Hotels
- Myrtle Beach Hotels
- Sumter Hotels
- Hotels near Florence Regional
- Hotels near Coker College
- Hotels near Mcleod Regional Medical Center
- Hotels near Francis Marion University
- Hotels near Florence Museum
- Hotels near Eastern Carolina Agricultural Fairgrounds
- Hotels near Magnolia Mall
- Hotels near Florence Civic Center
- Hotels near Florence Station
- Hotels near Florence Motor Speedway
- Hotels near South Carolina Cotton Museum
- Hotels near Lynches River State Park
- Hotels near Neptune Island Waterpark
- Hotels near Moore Farms Botanical Garden
- Downtown Charleston Hotels
- Williamsburg County Hotels
- Florence County Hotels
- Marion County Hotels
- Lee County Hotels
- Darlington County Hotels
- Last Minute Hotel Deals
- Last Minute Hotel Deals Las Vegas
- Last Minute Hotel Deals New York
- Last Minute Hotel Deals Chicago
- Last Minute Hotel Deals Honolulu
- Last Minute Hotel Deals Nashville
- Last Minute Hotel Deals Orlando
- Last Minute Hotel Deals Washington
- Last Minute Hotel Deals San Francisco
- Last Minute Hotel Deals Miami
- Last Minute Hotel Deals Denver
- Last Minute Hotel Deals Phoenix
- Last Minute Hotel Deals Austin
- Last Minute Hotel Deals Houston
- Last Minute Hotel Deals San Diego
- Last Minute Hotel Deals Fort Lauderdale
- Last Minute Hotel Deals Boston
- Last Minute Hotel Deals Los Angeles
- Last Minute Hotel Deals Dallas
- Last Minute Hotel Deals New Orleans
- Last Minute Hotel Deals Seattle