Hotels in Mayesville, South Carolina

Search & Compare Mayesville Hotels

Hotels.com® Rewards

Collect 10 nights, get 1 free night

And look out for Secret Prices on select hotels

  • Pay now or later on most rooms
  • Free cancellation on most rooms
  • Price Guarantee

Best hotels in Mayesville

With hotels.com we help you find the best hotels in Mayesville, South Carolina.

You can compare all of our Mayesville hotel rooms including the major Mayesville hotel chains using our genuine Hotels.com guest reviews as well as TripAdvisor Mayesville hotel reviews to help find the perfect hotel room when booking your accommodation in Mayesville. We also feature Expedia Mayesville hotels and reviews.

When you book your Mayesville stay with Hotels.com you may also earn free nights on participating hotels by joining the Hotels.com Welcome Rewards program. It's free to join and only takes 2 minutes to sign up and when you stay 10 nights you receive 1 night free*. So even a short weekend break in Mayesville can get you on your way to a free night.

Why use Hotels.com to book your Mayesville lodging & accommodation?

We can help you to find the perfect Mayesville hotel room for almost any occaision. With our fast and secure hotel search you may compare different Mayesville hotels by:

  • - Price
  • - Location within Mayesville
  • - Neighborhoods in Mayesville
  • - Nearby Mayesville attractions
  • - Hotels in different areas of South Carolina
  • - Genuine Hotels.com guest reviews for Mayesville
  • - Star rating
  • - Amenities
  • - Hotel name & chain
  • - Theme


For every hotel in Mayesville South Carolina we provide:

  • - Up to the minute hotel rates & availability
  • - In depth hotel information and photos
  • - Detailed Mayesville maps showing the locations of your hotel in Mayesville and the nearest transport and landmarks
  • - TripAdvisor Mayesville hotel review score


And when you make a hotel reservation in Mayesville with Hotels.com we'll send you email and text confirmations with the reservation details of your Mayesville hotel booking along with contact details, directions, information on nearby Mayesville attractions, restaurants and even the weather - and if you get stuck, we're only a phone call away.

To make the most of our service, download our mobile & tablet apps and sign up to our newsletter or follow us on Facebook, Google+ or Twitter to receive the latest deals and Hotels.com Mayesville discount codes.