Hotels in Eastern Iowa

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May 4 - May 5
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May 5 - May 6
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May 9 - May 11
In two weeks
May 16 - May 18

Where to stay in Eastern Iowa?

The Catfish Bend Inn & Spa
Casino

The Catfish Bend Inn & Spa

3.5 star property
9.0 out of 10, Wonderful, (214)
The price is $113
includes taxes & fees
$101 per night
May 11 - May 12
The Catfish Bend Inn & Spa
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Great weekend hotel deals in Eastern Iowa, IA

Showing deals for:May 16 - May 18

Image gallery for Isle Casino Hotel - Waterloo

Arcade

Isle Casino Hotel - Waterloo

3.0 star property
Waterloo
8.2/10Very Good (1,007 reviews)
Member Price available
Price is $219
per night
$517 total
includes taxes & fees
Isle Casino Hotel - Waterloo

Top neighborhoods in Eastern Iowa

Downtown Dubuque which includes a river or creek and modern architecture as well as a large group of people

Downtown Dubuque

Dubuque's Downtown Dubuque neighborhood is known for its restaurants and casinos, and entices visitors with attractions including Five Flags Center and Fourth Street Elevator.

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Downtown Dubuque

Top landmarks in Eastern Iowa

With my job, I usually end up in places that I would never usually seek out...like Iowa. Even still, there is beauty to be found. #takeahike

Maquoketa Caves State Park

Maquoketa Caves State Park is 6.7 mi (10.8 km) from central Maquoketa, why not stop by during your stay.

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Maquoketa Caves State Park

Learn more about Eastern Iowa

Eastern Iowa is applauded for its live music and museums with such cultural attractions as Cedar Rapids Museum of Art and Paramount Theatre. Visitors highlight this artistic city's university life while sights include Tuma Soccer Complex and Wapsipinicon State Park.

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Dubuque featuring a sunset, a bridge and a river or creek
A tranquil hotel pool encircled by beautiful arches, enhancing the ambiance for leisure and relaxation.

Summer Getaway Sale

Save 25% or more on select hotels, and earn 50% more rewards on all properties. Book by May 26 and travel by Sep 30, 2025. See terms*
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Frequently asked questions

What hotels do travelers like in Eastern Iowa?
Lavender Fields Inn B&B, So Dear to My Heart B&B and The Brown Street Inn are all properties that our guests really like.
Can I book a refundable accommodation in Eastern Iowa?
If you want the flexibility to change your travel plans to Eastern Iowa, most properties provide refundable* bookable rates. You can find these accommodations by searching our site and using the “fully refundable” filter to narrow down the results.
Which Eastern Iowa hotels do travelers like for their great location?
Our guests rave about the location of these properties: Graduate Iowa City, Stoney Creek Hotel Quad Cities - Moline and Hotel Julien Dubuque. For a quiet locale, travelers like The Highlander Hotel.
Where should I stay in Eastern Iowa if I'm looking for an affordable accommodation?
Two inexpensive options worth considering are Stoney Creek Hotel Quad Cities - Moline and Comfort Suites Coralville I-80. You can browse more choices on our site, including 37 motels.
Where can I stay in Eastern Iowa if I want a vacation home instead of a hotel?
If you want to find a good alternative to a hotel, browse our selection of 366 vacation homes. In addition, there are 104 apartments and 26 condos.
Why should I book my Eastern Iowa hotel through Hotels.com?
There are plenty of reasons to book your Eastern Iowa travel with us: our free cancellations on selected hotels* gives you the flexibility you’re looking for, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™** on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.

Terms and conditions

*Book by 5/26/2025 11:59 pm in hotel property local time. Stay between 4/17/2025-9/30/2025. Member Prices are available to Hotels.com® app users and One Key members. Limited availability, blackout periods may apply.

OneKeyCash is not redeemable for cash and can only be used on Hotels.com®, Expedia®, and Vrbo®.

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