Hotels in Mytilene

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Where to stay in Mytilene?

ISSA Lesvos

9.6 out of 10, Exceptional, (12)
ISSA Lesvos

Theofilos Paradise Boutique Hotel

4.0 star property
9.6 out of 10, Exceptional, (146)
Theofilos Paradise Boutique Hotel

Mythical Coast Wellness Retreat

5.0 star property
8.8 out of 10, Excellent, (31)
Mythical Coast Wellness Retreat

The Loriet

4.0 star property
8.4 out of 10, Very good, (64)
The Loriet

Ampoulos Rooms & Apartments

8.2 out of 10, Very good, (19)
Ampoulos Rooms & Apartments

Heliotrope Hotels

4.0 star property
8.6 out of 10, Excellent, (183)
Heliotrope Hotels

Hotel Lesvion

3.0 star property
9.6 out of 10, Exceptional, (89)
Hotel Lesvion

Studio 5

Studio 5

Elies Residences

10.0 out of 10, Exceptional, (29)
Elies Residences

Agora Apartments

10.0 out of 10, Exceptional, (1)
Agora Apartments

Heliotrope The Studios

8.8 out of 10, Excellent, (44)
Heliotrope The Studios

Nitelli's Houses

9.0 out of 10, Wonderful, (14)
Nitelli's Houses

Olive Green Studios and Apartments

10.0 out of 10, Exceptional, (1)
Olive Green Studios and Apartments

Vicky Studios

10.0 out of 10, Exceptional, (2)
Vicky Studios
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top landmarks in Mytilene

Learn more about Mytilene

Notable for its seaside, Mytilene features attractions such as Port of Mytilene and Mytilini Castle.

Check out reviews of Mytilene hotels guests love

Frequently asked questions

Can I book a refundable accommodation option in Mytilene?
If you want the flexibility to change your plans to Mytilene, most hotels offer refundable* rates that you can book. You can find this accommodation by searching our site and using the "fully refundable" filter to narrow down the results.
Where can I stay in Mytilene if I want a holiday rental instead of a hotel?
You'll find 13 holiday homes on our site. You can also book one of 23 apartments or 19 villas.
What will the weather in Mytilene be like during my visit?
The warmest months in Mytilene are usually August and July, with an average temperature of 25°C. January and February are the chilliest months, when the average temperature is 11°C. The rainiest months are January and December.
Why should I book my Mytilene hotel with Hotels.com?
There are plenty of reasons to book your Mytilene travel with us: our free cancellations on selected hotels* gives you the flexibility you're looking for, our Price Guarantee ensures that you always get the lowest price, and you can earn rewards on every booking.