Hotels in Mytilene

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Dates

July 2025

17

August 2025

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Where to stay in Mytilene?

Stunning building facade with three elegant doors and stone pillars.

Stunning multi-story building with a central entrance, balconies, and decorative elements.

Relax in a spacious room with a large window offering ocean views, a seating area with two chairs and a table.

Relax by the illuminated pool surrounded by comfortable seating areas.

Relax by the tranquil pool, surrounded by lounge chairs and umbrellas.

Enjoy breathtaking harbor views from this room's spacious balcony with a large window and comfortable seating for two.

Stairs lead up to a window with a view, flanked by a bicycle.

Relax by the pool surrounded by lush greenery and a clear sky.

Relax in a serene space with a neatly made bed, wooden headboard, and potted plants.

Relax in this inviting room with a sofa, wooden bench, and table, plus a comfortable bed and door to another space.

Relax on the beach with a serene view of the calm sea and lush green surroundings.

Relax in a stylish room with a large window offering a view of the sea, a comfortable bed, and a hot tub.

Stroll through our beautifully maintained garden, featuring a variety of colorful blooms and a tranquil pathway.

Go beyond your typical stay in Mytilene

Pool

Spa

Top landmarks in Mytilene

Port of Mytilene

Explore the waterfront in Mytilene with a trip to Port of Mytilene. While you're in the area, stroll along the seaside.

Learn more about Mytilene

Notable for its seaside, Mytilene features attractions such as Port of Mytilene and Mytilini Castle.

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Check out reviews of Mytilene hotels guests love

Theofilos Paradise Boutique Hotel

10/10 Excellent

"Hotel’s location is great. There are a lot of food/drinks options within minutes. It is located in a very lively part of the town, yet secluded for a quiet stay. The breakfast was also very good. "

Elies Residences

10/10 Excellent

"The sea view pool and the landscaping were so impressive and tranquil. Wish we could have stayed longer. The Molivos apartment was very nice and relaxing with 2 bedrooms , 2 bathrooms, 2 verandas, kitchen. LR, communal pool, 2 extra sunbeds on the grass under a tree, and parking. Perfect apartment for a family or friends. We are going again in July with our 21 and 23 year old children to have quality time. Marina and the staff were very friendly. There’s a little bar near the pool for drinks and toast which is convenient. "

Hotel Lesvion

10/10 Excellent

"We were made to feel welcome from the moment we arrived at reception. Owners and staff were friendly and helpful throughout our stay. Beds very comfortable. Sea view across bay was wonderful / a great place to ferry watch (although not too many ferries as it’s at the end of the line). Breakfast - excellent, large choice (ncludi g a lot of homemade) and plentiful."

Porto Lesvos

10/10 Excellent

"I have stayed here before and the owner is a very pleasant person who enjoys talking to his customers about a wide range of topics. I usually stay for one night and then go to Scala Kalloni inland. It is a place where Birders go in April and May to see the birds arriving from Africa & on their way to mainland Europe."

Frequently asked questions

Can I book a refundable accommodation option in Mytilene?

If you want the flexibility to change your plans to Mytilene, most hotels offer refundable* rates that you can book. You can find this accommodation by searching our site and using the "fully refundable" filter to narrow down the results.

Where can I stay in Mytilene if I want a holiday rental instead of a hotel?

You'll find 13 holiday homes on our site. You can also book one of 23 apartments or 19 villas.

What will the weather in Mytilene be like during my visit?

The warmest months in Mytilene are usually August and July, with an average temperature of 25°C. January and February are the chilliest months, when the average temperature is 11°C. The rainiest months are January and December.

Why should I book my Mytilene hotel with Hotels.com?

There are plenty of reasons to book your Mytilene travel with us: our free cancellations on selected hotels* gives you the flexibility you're looking for, our Price Guarantee ensures that you always get the lowest price, and you can earn rewards on every booking.

Find out more about Mytilene

If you're looking to discover somewhere new, look no further than Mytilene. Whether you're planning to stay for a night or for the week, the area around Mytilene has accommodation options to fit every need. Search for hotels in Mytilene with Hotels.com by checking our online map. Our map displays the areas and neighbourhoods around all Mytilene hotels so you can see how close you are from landmarks and attractions, and then refine your search within the larger area. The best Mytilene hotel deals are here with our lowest price guarantee.

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Guest Houses in Mytilene

Hotels near Mytilene Intl. Airport (MJT)

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Hotels in Mytilene

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Where to stay in Mytilene?

ISSA Lesvos