Hotels in Desdemona

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Tonight
May 16 - May 17
Tomorrow
May 17 - May 18
This weekend
May 16 - May 18
Next weekend
May 23 - May 25

Where to stay in Desdemona?

De Leon Inn
Vending machine

De Leon Inn

2.0 star property
7.8 out of 10, Good, (114)
$59 nightly
The price is $63
Jun 6 - Jun 7
Total includes taxes and fees
De Leon Inn
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
A tranquil hotel pool encircled by beautiful arches, enhancing the ambiance for leisure and relaxation.

Summer Getaway Sale

Save 25% or more on select hotels, and earn 50% more rewards on all properties. Book by May 26 and travel by Sep 30, 2025. See terms*
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Frequently asked questions

What accommodations do travelers like in Desdemona?
Guests like Allure 1900 sq waterfront home with country elegance spectacular views and Allure charming peaceful wooded Hill Country like views with easy Lake access.
Can I book refundable accommodations in Desdemona?
If you need the flexibility to change your travel plans to Desdemona, most hotels provide refundable* rates you can book. You can see these properties by searching our site and using the “fully refundable” filter to narrow the results down.
What will the weather in Desdemona be like during my vacation?
August and July are typically the warmest months in Desdemona when the average temp is 83°F. January and February are the coldest months when the average temperature is 51°F. May and October are the months with the most rain.
Why should I book my Desdemona accommodation with Hotels.com?
There are plenty of reasons to book your Desdemona travel with us: our free cancellations on selected hotels* gives you the flexibility you’re looking for, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™** on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.

Terms and conditions

*Book by 5/26/2025 11:59 pm in hotel property local time. Stay between 4/17/2025-9/30/2025. Member Prices are available to Hotels.com® app users and One Key members. Limited availability, blackout periods may apply.

OneKeyCash is not redeemable for cash and can only be used on Hotels.com®, Expedia®, and Vrbo®.

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