Hotels in Southeast Iowa

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Where to stay in Southeast Iowa?

The Catfish Bend Inn & Spa
Casino

The Catfish Bend Inn & Spa

3.5 star property
9.0 out of 10, Wonderful, (213)
The price is $111
includes taxes & fees
$99 per night
May 4 - May 5
The Catfish Bend Inn & Spa
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top landmarks in Southeast Iowa

Ripley's Believe or Not has coined Snake Alley as the crookedest road in the world. Built in 1894, cars still maneuver their way from the top to the bottom, an exhilarating experience worth seeking! #localgem

Snake Alley

Learn about the local history of Burlington when you take a trip to Snake Alley. Visit the area's casinos, or simply enjoy its bars.

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Snake Alley

Learn more about Southeast Iowa

Southeast Iowa is well-known for its riverfront and casinos, featuring attractions such as Battle of Athens State Historic Site and Bentonsport National Historic District. Visitors highlight this family-friendly city's sports while sights include Geode State Park and C.E. Richards Arena.

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A tranquil hotel pool encircled by beautiful arches, enhancing the ambiance for leisure and relaxation.

Summer Getaway Sale

Save 25% or more on select hotels, and earn 50% more rewards on all properties. Book by May 26 and travel by Sep 30, 2025. See terms*
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Frequently asked questions

What hotels do travelers like in Southeast Iowa?
Willard Richards Inn, Cobblestone Inn & Suites - Fort Madison and The Inn at Old Nauvoo are all properties that our guests really like.
Can I book a refundable hotel in Southeast Iowa?
If you want the flexibility to change your travel plans to Southeast Iowa, most accommodations offer refundable* bookable rates. You can find these accommodations by searching our site and using the “fully refundable” filter to narrow down the results.
Which Southeast Iowa hotels do guests like for their central location?
Our guests love these properties for their convenient location: AmericInn by Wyndham West Burlington, Fun City Resort Hotel and Quality Inn Burlington near Hwy 34.
Where can I stay in Southeast Iowa if I want a budget-friendly accommodation?
AmericInn by Wyndham West Burlington, Best Western Mt. Pleasant Inn and Comfort Suites Burlington are a few accommodations you might want to consider that’ll save you money. You can browse more choices on our site, including 6 motels.
Where can I stay in Southeast Iowa if I want a vacation rental instead of a traditional hotel?
If you want a good alternative to a hotel, browse our selection of 29 vacation homes. You also might want to consider one of 8 apartments or 7 cabins.
Why should I book my Southeast Iowa hotel with Hotels.com?
There are plenty of reasons to book your Southeast Iowa travel with us: our free cancellations on selected hotels* gives you the flexibility you’re looking for, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™** on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.

Terms and conditions

*Book by 5/26/2025 11:59 pm in hotel property local time. Stay between 4/17/2025-9/30/2025. Member Prices are available to Hotels.com® app users and One Key members. Limited availability, blackout periods may apply.

OneKeyCash is not redeemable for cash and can only be used on Hotels.com®, Expedia®, and Vrbo®.

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