Hotels in Panacea

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Where to stay in Panacea?

Properties are selected based on real traveler reviews and popularity among guests who’ve booked a night in Panacea on Hotels.com. These Panacea hotels consistently deliver on quality, location and traveler experience. Last updated on .

1. BOB Hotels Tallahassee - Boutique on Budget

BOB Hotels Tallahassee - Boutique on Budget
3.0 star property
Tallahassee
9.0 out of 10, Wonderful, (2,695 reviews)
$70 nightly
The price is $79
Nov 15 - Nov 16
Total with taxes and fees
BOB Hotels Tallahassee - Boutique on Budget

2. Hyatt House Tallahassee Capitol – University

Hyatt House Tallahassee Capitol – University
3.0 star property
Railroad Square Art District
9.0 out of 10, Wonderful, (1,789 reviews)
Art Deco style meets modern comfort at this centrally located hotel near Railroad Square Art Park. Cool off in the outdoor pool, grab dinner at H Bar, or keep up with workouts in the 24-hour fitness center.
$121 nightly
The price is $136
Dec 14 - Dec 15
Total with taxes and fees
Hyatt House Tallahassee Capitol – University

3. The Panacea Motel

The Panacea Motel
2.0 star property
Panacea
9.0 out of 10, Wonderful, (201 reviews)
Escape to this waterfront motel where adventure awaits with hiking trails and kayaking right on the property. Explore nearby Panacea Springs and Woolley Park before returning to enjoy free WiFi and parking. Just 47 minutes from Tallahassee Airport.
$116 nightly
The price is $130
Nov 24 - Nov 25
Total with taxes and fees
The Panacea Motel

4. Hotel Indigo Tallahassee - Collegetown by IHG

Hotel Indigo Tallahassee - Collegetown by IHG
3.5 star property
College Town
9.4 out of 10, Exceptional, (1,001 reviews)
Trendy hotel near Florida State and FAMU universities with a lively bar and R&R Eatery serving breakfast and dinner. Just minutes from Railroad Square Art Park, this convenient location offers a 24-hour fitness center and is praised for its helpful staff.
$114 nightly
The price is $128
Dec 13 - Dec 14
Total with taxes and fees
Hotel Indigo Tallahassee - Collegetown by IHG

5. Wildwood Inn

Wildwood Inn
3.0 star property
Crawfordville
8.6 out of 10, Excellent, (1,001 reviews)
$111 nightly
The price is $123
Dec 13 - Dec 14
Total with taxes and fees
Wildwood Inn

6. The Lodge at Wakulla Springs

The Lodge at Wakulla Springs
3.0 star property
Crawfordville
9.6 out of 10, Exceptional, (1,000 reviews)
Set in Wakulla Springs State Park, this historic hotel offers American cuisine at Edward Ball Dining Room and outdoor adventures with a terrace for relaxing. Enjoy free WiFi and parking with easy access to Wakulla State Forest and Tallahassee.
$111 nightly
The price is $123
Dec 3 - Dec 4
Total with taxes and fees
The Lodge at Wakulla Springs

7. Four Points by Sheraton Tallahassee Downtown

Four Points by Sheraton Tallahassee Downtown
3.0 star property
Governor's Walk
8.6 out of 10, Excellent, (1,236 reviews)
Experience convenient comfort near Florida State and Florida A&M universities, just a short drive away. Take a refreshing dip in the outdoor pool, dine at Juicy Blue restaurant, or unwind at one of 2 bars. Guests love the comfortable beds, helpful staff, and free parking.
$114 nightly
The price is $128
Nov 29 - Nov 30
Total with taxes and fees
Four Points by Sheraton Tallahassee Downtown

8. Best Western Wakulla Inn & Suites

Best Western Wakulla Inn & Suites
2.5 star property
Crawfordville
8.8 out of 10, Excellent, (1,002 reviews)
$108 nightly
The price is $120
Nov 29 - Nov 30
Total with taxes and fees
Best Western Wakulla Inn & Suites

9. Courtyard by Marriott Tallahassee Downtown/Capitol

Courtyard by Marriott Tallahassee Downtown/Capitol
3.0 star property
Tallahassee
8.4 out of 10, Very good, (1,000 reviews)
Close to FSU and FAMU, this Courtyard by Marriott offers a quiet retreat with an outdoor pool and The Bistro serving American fare. Myers Park and Parkway Shopping Center are nearby, plus you'll enjoy free WiFi and parking.
$88 nightly
The price is $99
Nov 29 - Nov 30
Total with taxes and fees
Courtyard by Marriott Tallahassee Downtown/Capitol

10. St James Bay Golf & Pickleball Resort

St James Bay Golf & Pickleball Resort
3.5 star property
Carrabelle
9.0 out of 10, Wonderful, (434 reviews)
Escape to this Carrabelle resort offering an 18-hole golf course, outdoor pool, and rejuvenating massages. After a round, relax at the bar or dine at the restaurant. Rooms include washers, dryers, and microwaves for added comfort during your stay.
$131 nightly
The price is $145
Nov 25 - Nov 26
Total with taxes and fees
St James Bay Golf & Pickleball Resort

11. Aloft by Marriott Tallahassee Downtown

Aloft by Marriott Tallahassee Downtown
3.0 star property
Capitol Hill
9.0 out of 10, Wonderful, (1,002 reviews)
Experience urban comfort near Florida's universities with an outdoor pool and WXYZ restaurant serving breakfast and dinner. The fitness center and bar/lounge enhance your stay, while helpful staff ensure a pleasant visit close to downtown attractions.
$125 nightly
The price is $141
Nov 23 - Nov 24
Total with taxes and fees
Aloft by Marriott Tallahassee Downtown

12. stayAPT Suites Tallahassee-Capitol

stayAPT Suites Tallahassee-Capitol
3.5 star property
Tallahassee
8.6 out of 10, Excellent, (216 reviews)
This modern aparthotel offers apartments with fully equipped kitchens including refrigerators and islands. Myers Park and Parkway Shopping Center are nearby, while free WiFi, parking, and on-site laundry make extended stays effortless.
$99 nightly
The price is $111
Nov 15 - Nov 16
Total with taxes and fees
stayAPT Suites Tallahassee-Capitol

13. Home2 Suites by Hilton Tallahassee State Capitol

Home2 Suites by Hilton Tallahassee State Capitol
3.0 star property
Tallahassee
8.2 out of 10, Very good, (1,000 reviews)
Travelers praise the helpful staff at this hotel featuring a 24-hour fitness center and outdoor pool. Just a short drive from Parkway Shopping Center, Governor's Square Mall, and Tallahassee Station, with free breakfast and WiFi.
$110 nightly
The price is $123
Nov 29 - Nov 30
Total with taxes and fees
Home2 Suites by Hilton Tallahassee State Capitol

14. Fairfield by Marriott Inn & Suites Tallahassee Central

Fairfield by Marriott Inn & Suites Tallahassee Central
3.0 star property
Tallahassee
8.6 out of 10, Excellent, (1,001 reviews)
$93 nightly
The price is $104
Nov 17 - Nov 18
Total with taxes and fees
Fairfield by Marriott Inn & Suites Tallahassee Central

15. Hotel Duval, Autograph Collection

Hotel Duval, Autograph Collection
4.0 star property
Governor's Walk
8.0 out of 10, Very good, (1,005 reviews)
Enjoy panoramic views from the rooftop terrace at this Tallahassee hotel near Florida State and A&M universities. With 2 bars, a café, and 24-hour fitness center, you're perfectly positioned to explore the Florida Governor's Mansion and LeMoyne Art Gallery.
$115 nightly
The price is $130
Nov 22 - Nov 23
Total with taxes and fees
Hotel Duval, Autograph Collection

16. Holiday Inn Tallahassee E Capitol - Univ by IHG

Holiday Inn Tallahassee E Capitol - Univ by IHG
3.0 star property
Tallahassee
9.2 out of 10, Wonderful, (1,000 reviews)
Discover a convenient Tallahassee hotel near FSU and Florida A&M University. The indoor pool and 24-hour fitness center offer year-round relaxation while Capitol Cafe & Bar serves American cuisine. Rooms include refrigerators and microwaves for added comfort.
$107 nightly
The price is $120
Dec 13 - Dec 14
Total with taxes and fees
Holiday Inn Tallahassee E Capitol - Univ by IHG

17. Hampton Inn & Suites Tallahassee Capitol - University

Hampton Inn & Suites Tallahassee Capitol - University
2.5 star property
Railroad Square Art District
9.0 out of 10, Wonderful, (1,001 reviews)
Kick back at this Tallahassee hotel near Florida State University and Florida A&M. The outdoor pool offers refreshing dips after exploring Railroad Square Art Park. With free breakfast, WiFi, and Tallahassee Station just 2 minutes away, adventure awaits.
$118 nightly
The price is $133
Nov 23 - Nov 24
Total with taxes and fees
Hampton Inn & Suites Tallahassee Capitol - University

18. Hilton Garden Inn Tallahassee Central

Hilton Garden Inn Tallahassee Central
3.0 star property
Tallahassee
8.2 out of 10, Very good, (838 reviews)
Unwind at this Tallahassee hotel within minutes of FSU and FAMU. After exploring nearby Governor's Square Mall, cool off in the outdoor pool or grab American cuisine at The Garden Grille & Bar. Rooms offer microwaves and refrigerators.
$93 nightly
The price is $104
Dec 6 - Dec 7
Total with taxes and fees
Hilton Garden Inn Tallahassee Central

19. Comfort Suites Tallahassee Capitol - University Area

Comfort Suites Tallahassee Capitol - University Area
2.5 star property
Tallahassee
8.2 out of 10, Very good, (1,001 reviews)
This peaceful hotel sits just minutes from Florida State and Florida A&M universities. Enjoy the outdoor pool after exploring nearby Myers Park. Complimentary perks include WiFi, parking, and breakfast that guests consistently praise alongside the helpful staff.
$86 nightly
The price is $97
Nov 22 - Nov 23
Total with taxes and fees
Comfort Suites Tallahassee Capitol - University Area

20. The Old Carrabelle Hotel

The Old Carrabelle Hotel
2.0 star property
Carrabelle
9.6 out of 10, Exceptional, (56 reviews)
$126 nightly
The price is $140
Nov 30 - Dec 1
Total with taxes and fees
The Old Carrabelle Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

When is the best time to visit Panacea?

Our prices for hotels in Panacea are cheapest in February
Price trends for hotels in Panacea
Pricing is based on two traveler single night rates
View properties in November
Currently viewing crowd sizes and weather for November.
Typical weather for Panacea
November
High 71°F / low 55°F. Sunny most days.
View properties in November
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November, no crowd data, average high temperature 71 degrees Fahrenheit, average low temperature 55 degrees Fahrenheit. Sunny most days.
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December, no crowd data, average high temperature 65 degrees Fahrenheit, average low temperature 51 degrees Fahrenheit. Sunny most days.
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January, no crowd data, average high temperature 62 degrees Fahrenheit, average low temperature 46 degrees Fahrenheit. Sunny most days.
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66°
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February, no crowd data, average high temperature 66 degrees Fahrenheit, average low temperature 50 degrees Fahrenheit. Sunny most days.
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72°
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March, no crowd data, average high temperature 72 degrees Fahrenheit, average low temperature 55 degrees Fahrenheit. Sunny most days.
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77°
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April, no crowd data, average high temperature 77 degrees Fahrenheit, average low temperature 61 degrees Fahrenheit. Sunny most days.
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May, no crowd data, average high temperature 84 degrees Fahrenheit, average low temperature 67 degrees Fahrenheit. Sunny most days.
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June, no crowd data, average high temperature 88 degrees Fahrenheit, average low temperature 74 degrees Fahrenheit. Partly sunny.
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July, no crowd data, average high temperature 89 degrees Fahrenheit, average low temperature 76 degrees Fahrenheit. Partly sunny.
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August, no crowd data, average high temperature 89 degrees Fahrenheit, average low temperature 76 degrees Fahrenheit. Partly sunny.
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September, no crowd data, average high temperature 86 degrees Fahrenheit, average low temperature 73 degrees Fahrenheit. Sunny most days.
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80°
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October, no crowd data, average high temperature 80 degrees Fahrenheit, average low temperature 64 degrees Fahrenheit. Sunny most days.
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Monthly weather averages (˚F)

Top landmarks in Panacea

Learn more about Panacea

Notable for its natural beauty, Panacea features attractions such as Mashes Sand Beach and Alligator Point Beach. This beachside city has something for everyone including seafood restaurants as well as sights like Bald Point State Park and Wilson Beach. All are within a secluded setting.

A coastal resort with beachfront villas and a clear blue sky.

Check out reviews of Panacea hotels guests love

Frequently asked questions

How much does a hotel room cost in Panacea?
You can find top hotels in Panacea from $105 with options to suit your budget and needs. If you're looking for an affordable hotel in Panacea that meets all of your requirements, just sort hotels by "Price: low to high" after applying your filters when searching on Hotels.com.
How can I find deals and earn rewards at Panacea hotels?
Discover great deals on Panacea hotel stays with Hotels.com. Take a look at hotel prices mid-week or during the low season as to find those off-peak deals. And make sure to check out our last-minute deals on Panacea hotels.
Can I book Panacea hotels with free cancellation?
To book a refundable Panacea hotel on Hotels.com, just filter hotels by "Property cancellation options" and select "Fully refundable property". Many hotels offer free cancellation, so you can receive a refund if you need to cancel. Some hotels do require cancelling more than 24 hours before check-in, so double-check your booking beforehand.
What hotels do travelers like in Panacea?
Guests like The Panacea Motel.
Can I book a refundable accommodation in Panacea?
If you're looking for the flexibility to change your travel plans to Panacea, most accommodations offer refundable* bookable rates. You can find these accommodations by searching our site and using the "fully refundable" filter to narrow the results down.
Where can I stay in Panacea if I want a vacation home instead of a traditional hotel?
If you want a good alternative to a hotel, browse our selection of 177 vacation homes. In addition, there are 17 apartments and 10 condos.
What will the weather in Panacea be like during my visit?
July and August are typically the warmest months in Panacea when the average temp is 81°F. January and February are the coldest months when the average temperature is 58°F. August and July are the months with the most rain.
Why should I book my Panacea hotel through Hotels.com?
There are lots of reasons to book your Panacea trip with us: our free cancellations on selected hotels gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.

Find out more about Panacea

Whispers of the Waves: Discover Nature's Embrace at Panacea

Nestled along Florida's tranquil coast, Panacea is a hidden gem for nature lovers and beach enthusiasts alike. This charming destination offers stunning views of the Gulf of Mexico, pristine beaches, and the enchanting wildlife of nearby Panacea Springs. Explore the lush wetlands and vibrant ecosystems, perfect for kayaking and birdwatching. Immerse yourself in the local charm with cozy accommodations and fresh seafood dining. With its serene atmosphere and abundant outdoor activities, Panacea invites you to unwind and reconnect with nature, making it an idyllic escape from the ordinary. Discover the soothing allure of this off-the-beaten-path paradise.

Discover great hotels near Panacea

Panacea, Florida, offers a range of accommodations from cozy motels to charming inns, ideal for travelers seeking a laid-back experience. Whether you prefer beachfront views or convenient access to local attractions, you’ll find various options to suit your preferences for a relaxing getaway. Here are some of our travelers' favorite hotels near Panacea:

  1. Best Western Wakulla Inn & SuitesOpens in a new window: This budget-friendly hotel boasts a commendable guest rating of 8.8 out of 10 and is ideal for adventure travelers seeking an active getaway. Guests can indulge in a range of recreational activities, including nearby hiking, biking, snorkeling, and sailing. The hotel features clean and comfortable accommodations, complemented by a delightful breakfast offering a variety of hot options. Travelers appreciate the tranquil setting, allowing for relaxation after a long journey, making it a perfect retreat for those looking to rejuvenate in a peaceful environment.
  2. Wildwood InnOpens in a new window: With a guest rating of 8.6 out of 10, this 3.0-star hotel caters to adventure seekers and pet lovers alike. The property stands out with its selection of nearby activities, such as fishing, snorkeling, and sailing. Guests enjoy clean and efficient rooms, as well as a breakfast experience that is consistently praised. The friendly atmosphere and efficient service enhance the overall experience, ensuring that visitors have everything they need for a comfortable and enjoyable stay.
  3. St James Bay Golf & Pickleball ResortOpens in a new window: This charming 3.5-star hotel offers a delightful experience with a guest rating of 9.0 out of 10, appealing primarily to leisure travelers with a passion for golf. The property showcases beautiful surroundings and well-appointed cottages, providing a unique retreat. Guests can indulge in exceptional dining at the hotel's restaurant and enjoy access to golfing experiences in a serene atmosphere. The combination of stunning scenery and excellent amenities creates a memorable escape for those seeking relaxation and adventure in one setting.

Where to stay in and around Panacea

In Panacea, Florida, great areas to stay include Alligator Point, Crawfordville, and Saint Teresa. Alligator Point offers stunning coastal views and tranquil beaches, while Crawfordville is known for its natural beauty and outdoor activities. Saint Teresa features a charming, laid-back atmosphere. For first-time visitors, Crawfordville is best suited, providing a mix of convenience and local attractions.

  1. CrawfordvilleOpens in a new window: Crawfordville is a charming spot for travelers looking to immerse themselves in nature. Nestled close to the pristine waters of the Gulf, this area is known for its beautiful parks and outdoor recreational activities. You can explore the nearby Wakulla Springs State Park, famous for its clear waters and wildlife, or enjoy hiking and biking along scenic trails. The local shops and markets offer a taste of the community, where you can find unique crafts and regional products. With its friendly vibe and natural beauty, Crawfordville is perfect for those seeking a laid-back getaway.
  2. Alligator PointOpens in a new window: Alligator Point is a hidden gem for beach lovers and those who appreciate a peaceful atmosphere. This quaint coastal area boasts stunning beaches and breathtaking sunsets, making it ideal for relaxing strolls or picnics by the shore. Enjoy fishing, kayaking, or simply soaking up the sun on the sandy beaches. It’s a great spot to unwind and disconnect from the hustle and bustle, with charming local spots to explore and a friendly community that welcomes visitors.
  3. Saint TeresaOpens in a new window: Saint Teresa is a picturesque destination that offers a serene beach experience, perfect for a tranquil escape. Known for its soft sandy shores and calm waters, it's ideal for swimming, sunbathing, or just enjoying a book by the beach. The area has a cozy, close-knit feel and is perfect for families or couples looking for a quiet retreat. Outdoor enthusiasts can also enjoy nearby nature trails and scenic views, making it a delightful choice for those wanting to relax and recharge amidst nature's beauty.

Things to do in Panacea

Panacea for travelers offers a stunning blend of pristine beaches, lush forests, and serene lakes. Experience thrilling activities like boating with playful dolphins, fishing in tranquil waters, and hiking through scenic trails. As the sun sets, the vibrant colors create a breathtaking backdrop for memorable moments in nature.

  • Ochlockonee River State ParkOpens in a new window – Dive into nature at Ochlockonee River State Park, where you can kayak along serene waters or hike through lush trails. This park is a haven for wildlife enthusiasts and offers a peaceful retreat to enjoy Florida's natural beauty.
  • Alligator Point BeachOpens in a new window – Spend a relaxing day at Alligator Point Beach, where soft sands and gentle waves create the perfect setting for sunbathing, picnicking, or beachcombing. Keep an eye out for dolphins playing in the surf as you soak up the sun.
  • Shell Point BeachOpens in a new window – Shell Point Beach invites you to explore its tidal pools and collect unique seashells. It's an ideal spot for families, with shallow waters perfect for wading and a picturesque landscape that’s great for photography.
  • Wakulla Springs State ParkOpens in a new window – Experience the crystal-clear waters of Wakulla Springs State Park, one of the largest and deepest freshwater springs in the world. Take a guided boat tour to see manatees and alligators in their natural habitat, or enjoy the scenic trails surrounding the spring.
  • St. Marks National Wildlife RefugeOpens in a new window – Discover diverse ecosystems at St. Marks National Wildlife Refuge, where you can hike or bike along trails that lead to stunning views of salt marshes and coastal habitats. Birdwatchers will find this area particularly rewarding, with numerous species to spot.

5 tips for savvy savings when booking a hotel in Panacea

  1. Book for the cheapest times: The most budget-friendly months to visit Panacea are January, July, and December, when hotel prices are typically lower. For a great value for money experience, staying for at least 2 to 3 days is recommended to fully explore the area’s key landmarks, historical sites, and cultural attractions. Visitors can enjoy relaxing on the beach, spotting dolphins, indulging in fresh seafood, and experiencing the serene beauty of nature, which includes opportunities for fishing, wildlife observation, and breathtaking sunsets.
  2. Instant discounts. Rewards for later: Save up to 20% instantly on hundreds of thousands of properties with Member Discounts. Then earn rewards on eligible stays to use on future trips. Book once, win twice, get instant discounts and rewards. Join for freeOpens in a new window.
  3. Score last-minute deals on Hotels.com: Last-minute travel doesn't mean last-minute stress. Hotels.com's Last-Minute DealsOpens in a new window offer discounted rates close to your travel date, so the later you leave it, the more you could save. Turn on push notifications and you'll be the first to know when dealsOpens in a new window drop for Panacea.
  4. Book with confidence, not guesswork: Prices in Panacea shift with the season, local events, and how far out you book — but you don't have to guess. Hotels.com shows you the full price upfront with no surprises at checkout, and our price tracker tells you whether your dates are above or below average. So if you're flexible, you can shift your trip by a day or two to avoid peak season prices, compare pricesOpens in a new window and know you're getting a good deal before you commit.
  5. Think beyond the city center: Central hotels may come with a central price tag. A well-connected neighborhood a little further out may cut your hotel bill and can often give you a more local experience. Use Hotels.com's map view to find the sweet spot between location and value, and filter by price to see what's available across Panacea.

Best time to go to Panacea

Panacea experiences its lowest average temperature in January, at 53.6°F (12.0°C), while July to August are the hottest months, with an average temperature of 81.7°F (27.6°C). August is usually the wettest month. April, June, and July are the peak travel months in Panacea, attracting a higher number of tourists. During this peak period, the weather is mostly sunny, accompanied by light to moderate rainfall. On the other hand, October to December tend to be quieter times to visit, marked by light rainfall and mostly sunny conditions.

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