Hotels in Mytilene

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Tonight
May 9 - May 10
Tomorrow
May 10 - May 11
This weekend
May 9 - May 11
Next weekend
May 16 - May 18

Where to stay in Mytilene?

Theofilos Paradise Boutique Hotel
Property entrance

Theofilos Paradise Boutique Hotel

4.0 star property
9.6 out of 10, Exceptional, (137)
$124 nightly
The price is $147
May 11 - May 12
Total includes taxes and fees
Theofilos Paradise Boutique Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top landmarks in Mytilene

Port of Mytilene

Imagine strolling along Port of Mytilene for some great waterfront pics when in the heart of Mytilene. If you carry on walking you'll get to Plaz Tsamákia and Fykiótrypa for some more water views.

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Port of Mytilene

Learn more about Mytilene

Notable for its seaside, Mytilene features attractions such as Port of Mytilene and Mytilini Castle.

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A tranquil hotel pool encircled by beautiful arches, enhancing the ambiance for leisure and relaxation.

Summer Getaway Sale

Save 25% or more on select hotels, and earn 50% more rewards on all properties. Book by May 26 and travel by Sep 30, 2025. See terms*
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Frequently asked questions

What hotels do travelers like in Mytilene?
Hotel Lesvion, Theofilos Paradise Boutique Hotel and Heliotrope Hotels are all accommodations that are popular with guests.
Where can I get free parking at my hotel in Mytilene?
These hotels offer the perk of free parking: Theofilos Paradise Boutique Hotel and Heliotrope Hotels.
Can I book a refundable hotel in Mytilene?
If you need the flexibility to change your travel plans to Mytilene, most properties offer refundable* bookable rates. You can find these accommodations by searching our site and using the “fully refundable” filter to narrow down the results.
Where can I stay with my pet in Mytilene?
Your furry friend can stay with you at these pet-friendly hotels: Theofilos Paradise Boutique Hotel, Heliotrope Hotels and Heliotrope The Studios. There are 10 alternatives to choose from on our site.
Which Mytilene hotels do our guests like for their great location?
Travelers like these properties for their good location: Heliotrope Hotels and Hotel Lesvion.
Where can I stay in Mytilene if I'm looking for a cheap accommodation?
Porto Lesvos is an accommodation you might want to consider that’ll save you money.
Where can I stay in Mytilene if I want a vacation home instead of a hotel?
You’ll find 13 vacation homes on our site. You can also book one of 23 apartments or 18 villas.
Where can I stay if I'm visiting Mytilene with my family?
Parents traveling with children may want to consider Heliotrope The Studios and Galazio Asteri I.
Where should I stay in Mytilene for a vacation with my partner?
Mythical Coast Wellness Retreat, Elysion Hotel and Zaira Hotel are a few good options for a romantic getaway with your special someone.
Where should I stay in Mytilene if I'm looking for a luxury hotel?
A couple of options for a luxurious stay include Mythical Coast Wellness Retreat and Elysion Hotel.
What will the weather in Mytilene be like during my vacation?
The warmest months in Mytilene are usually August and July with an average temp of 77°F. January and February are the chilliest months when the average temp is 52°F. The rainiest months are January and December.
Why should I book my Mytilene hotel through Hotels.com?
There are plenty of reasons to book your Mytilene travel with us: our free cancellations on selected hotels* gives you the flexibility you’re looking for, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™** on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.

Terms and conditions

*Book by 5/26/2025 11:59 pm in hotel property local time. Stay between 4/17/2025-9/30/2025. Member Prices are available to Hotels.com® app users and One Key members. Limited availability, blackout periods may apply.

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