Hannibal is a family-friendly place known for its restaurants. Take in the local culture of Hannibal at Molly Brown Museum and Home and Mark Twain Boyhood Home and Museum. While you're in town, don't miss a chance to see sights like Rockcliffe Mansion and Mark Twain Memorial Lighthouse.
Hotels in Hannibal
Free cancellation options if plans change
Earn rewards on every night you stay
Save more with Member Prices
Check prices for these dates
Where to stay in Hannibal?

Sleep Inn & Suites
Sleep Inn & Suites
9.6 out of 10, Exceptional, (1000)

Days Inn by Wyndham Hannibal
Days Inn by Wyndham Hannibal
7.2 out of 10, Good, (170)

Motel 6 Hannibal, MO
Motel 6 Hannibal, MO
7.6 out of 10, Good, (1008)

Best Western On The River
Best Western On The River
8.6 out of 10, Excellent, (1002)

Super 8 by Wyndham Hannibal
Super 8 by Wyndham Hannibal
7.2 out of 10, Good, (1007)

Quality Inn & Suites Hannibal
Quality Inn & Suites Hannibal
7.8 out of 10, Good, (1005)

Garden House Bed and Breakfast
Garden House Bed and Breakfast
8.4 out of 10, Very good, (21)

Comfort Inn & Suites - Hannibal
Comfort Inn & Suites - Hannibal
7.6 out of 10, Good, (608)

Baymont by Wyndham Hannibal
Baymont by Wyndham Hannibal
6.2 out of 10, (668)

Riverside Inn Hannibal
Riverside Inn Hannibal
9.4 out of 10, Exceptional, (124)

Howard Johnson BY Wyndham Hannibal
Howard Johnson BY Wyndham Hannibal
7.2 out of 10, Good, (123)

Lighthouse Inn & Suites
Lighthouse Inn & Suites
9.0 out of 10, Wonderful, (11)

FairBridge Inn Express, Monroe City
FairBridge Inn Express, Monroe City
8.8 out of 10, Excellent, (398)

Heritage Hotel Quincy
Heritage Hotel Quincy
8.8 out of 10, Excellent, (113)

River's Edge Motel
River's Edge Motel
9.0 out of 10, Wonderful, (329)

Stoney Creek Inn Quincy
Stoney Creek Inn Quincy
8.8 out of 10, Excellent, (1001)

Town & Country Inn and Suites
Town & Country Inn and Suites
9.2 out of 10, Wonderful, (840)

Holiday Inn Quincy East by IHG
Holiday Inn Quincy East by IHG
8.8 out of 10, Excellent, (576)

Quality Inn & Suites Quincy - Downtown
Quality Inn & Suites Quincy - Downtown
8.8 out of 10, Excellent, (426)

AmericInn by Wyndham Quincy
AmericInn by Wyndham Quincy
7.4 out of 10, Good, (251)
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Go beyond your typical stay in Hannibal
Pet friendly
Top landmarks in Hannibal

Mark Twain Boyhood Home and Museum
Find out about the history of Hannibal with a stop at Mark Twain Boyhood Home and Museum. While in this family-friendly area, you can savour the top-notch restaurants.
Hannibal and related destinations
Hannibal is well known for its museums and riverfront, featuring attractions such as Rockcliffe Mansion and Molly Brown Museum and Home. Visitors to this historical city speak highly of the restaurants whereas sights include Mark Twain Boyhood Home and Museum and Mark Twain Memorial Lighthouse.

Check out reviews of Hannibal hotels guests love

Days Inn by Wyndham Hannibal
10/10 Excellent
Frequently asked questions
Find out more about Hannibal
Find out more about Hannibal
Keep exploring
Keep exploring
- Landmarks
- Star Rating
- Facilities
- Hotels close to nearby airports
- Nearby cities
- Top Cities in United States of America
- More Hotels
- Hotels near Mark Twain Cave
- Hotels near Mark Twain Boyhood Home and Museum
- Hotels near Mark Twain Cave and Cameron Cave
- Hotels near Rockcliffe Mansion
- Hotels near Hannibal Regional Hospital
- Hotels near Lovers Leap
- Hotels near Mark Twain Memorial Lighthouse
- Hotels near Molly Brown Museum and Home
- Hotels near Big River Train Town
- Hotels near Sawyer's Creek Fun Park
- Hotels near Planters Barn Theater
- Hotels near Jim's Journey: The Huck Finn Freedom Center
- Hotels near Bluff City Theater
- Hotels near Sodalis Nature Preserve
- Las Vegas Hotels
- New York Hotels
- Orlando Hotels
- Myrtle Beach Hotels
- Chicago Hotels
- San Diego Hotels
- Panama City Beach Hotels
- Destin Hotels
- Ocean City Hotels
- Los Angeles Hotels
- Miami Hotels
- Boston Hotels
- Gulf Shores Hotels
- Nashville Hotels
- Atlantic City Hotels
- Pigeon Forge Hotels
- Virginia Beach Hotels
- Atlanta Hotels
- San Francisco Hotels
- Houston Hotels