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Twentyone Hotel, Rome

4-star4 stars
Via Cola di Rienzo 23RomeRM00192Italy

4-star hotel with restaurant, near Piazza del Popolo
  • Free hot/cold buffet breakfast and free WiFi
  • Luxury Hotel
Very Good8.2
Great location
Tasty breakfast
More comfort would be nice
327See all 327 reviews
From 1,670 reviewsTripAdvisor Traveller Rating

Twentyone Hotel, Rome

from $96
  • Double Room Single Use
  • Economy Double or Twin Room
  • Standard Double Room
  • Deluxe Double or Twin Room
  • Family Suite
  • Double Room
  • Standard Triple Room
  • Double Room Single Use
  • Standard Twin Room, 2 Twin Beds
  • Junior Suite

About Twentyone Hotel, Rome

Contemporary design hotel, on the Vatican side of the river

Vatican side of Tiber
Located 2 blocks away from the river Tiber, the stylish Hotel Twenty One is in an ideal location for guests who want to be able to walk to top sights. It's a 20-minute walk west to St. Peter's Square, the same distance east to the Spanish Steps, on the opposite side of the river.

Walk or ride
You'll be in a safe, quiet neighborhood, with plenty of restaurants and cafés all around. Lepanto Metro Station is a 5-minute walk, and can take you to sights that are farther afield, like the Colosseum.

Free breakfast and WiFi
A modern hotel, the decor is sleekly monochromatic from lobby to rooms. There's a free breakfast and free WiFi in the lobby, 2 features guests appreciate. You can enjoy a nightcap in the bar, and airport transfers and onsite parking can be arranged at the 24-hour concierge desk. A restaurant is also available onsite.

Back in black
Rooms are spacious and design-conscious; contemporary touches include jet-black beds, lightened up by white designer furniture and colorful abstract art. You can expect amenities such as minibars, satellite TV, and free Internet in every room.

At a glance

Key facts

Hotel size

  • This hotel has 86 rooms
  • This hotel is arranged over 8 floors


  • Check-in time 2 PM-midnight
  • Check-out time is 11 AM
  • Express check-in

Required at check in

  • Credit card or cash deposit required

  • Government-issued photo ID required

Travelling with others


  • One child (3 years old and younger) stays free when occupying the parent or guardian's room, using existing bedding


  • Pets not allowed


  • Free WiFi and wired Internet access in public areas

  • Free WiFi and wired Internet access in rooms



  • Airport shuttle *


  • Self parking *
* See small print for additional details or extra charges

In the hotel

Food and drink
  • Free hot/cold buffet breakfast daily
  • Restaurant
  • Bar/lounge
  • Room service (during limited hours)
Things to do
  • Scooter/moped rentals nearby
Working away
  • Conference space
  • 24-hour front desk
  • Tours/ticket assistance
  • Limo or Town Car service available
  • Dry cleaning/laundry service
  • Laundry facilities
  • Luggage storage
  • Multilingual staff
  • Porter/bellhop
  • Year Built 2009
  • Elevator/lift
  • Television in common areas
  • Accessible bathroom
  • In-room accessibility
  • Roll-in shower

In the room

Home comforts
  • In-room climate control (air conditioning)
  • Air conditioning
  • Minibar
  • Iron/ironing board (on request)
Sleep well
  • Premium bedding
Freshen up
  • Private bathroom
  • Shower only
  • Bidet
  • Free toiletries
  • Hair dryer
Be entertained
  • Flat-screen TV
  • Pay movies
  • Premium TV channels
Stay connected
  • Desk
  • Free WiFi
  • Phone
Food and drink
  • Refrigerator
  • Daily housekeeping
  • In-room safe

Twentyone Hotel, Rome’s small print

Also known as

  • Hotel Twentyone
  • Twentyone Hotel
  • Twentyone Hotel Rome
  • Twentyone Rome


All guests, including children, must be present at check-in and show their government-issued photo ID card or passport.

Cash transactions at this property cannot exceed EUR 2999.99, due to national regulations. For further details, please contact the property using information in the booking confirmation.

Mandatory fees

You’ll be asked to pay the following charges at check in or check out:

  • A tax is imposed by the city: EUR 6 per person, per night, up to 10 nights. This tax does not apply to children under 10 years of age.

Optional extras

Self parking costs EUR 20 per day

Airport shuttle service is offered for an extra charge of EUR 60 per vehicle (one way)

We have included all charges provided to us by this hotel. However, charges can vary, for example, based on length of stay or the room you book.

What’s around Twentyone Hotel, Rome


  • In Prati
  • St. Peter's Basilica - 21 min walk
  • Piazza del Popolo - 8 min walk
  • Castel Sant'Angelo - 15 min walk
  • Piazza Navona - 17 min walk
  • Vatican Museums - 19 min walk
  • Pantheon - 20 min walk
  • Villa Borghese - 21 min walk

Getting around

  • Rome (FCO-Fiumicino - Leonardo da Vinci Intl.) - 29 min drive
  • Rome (CIA-Ciampino) - 30 min drive
  • Rome San Pietro Station - 8 min drive
  • Rome Termini Station - 9 min drive
  • Rome Balduina Station - 12 min drive
  • Lepanto Station - 8 min walk
  • Ottaviano - San Pietro - Musei Vaticani Station - 14 min walk
  • Spagna Station - 20 min walk
  • Self parking (surcharge)
  • Airport shuttle (surcharge)

Recent reviews

Very Good 8.2 From 327 reviews

Twentyone Hotel, Rome
A Traveler, us3 night trip
Twentyone Hotel, Rome
Great service and location. Only need more light
Everything was great. Best customer service, especially from Rita, good location, room is clean. Just one suggestion for the hotel: the lighting is a bit too dark, i have a hard time doing any reading in the room. Adding additional lightings will be fantastic
Clement, us4 night romance trip
Twentyone Hotel, Rome
Perfect place for a first time traveler to Rome
We could not hve picked a better hotel for the part of our trip focused on the Vatican, Borghese Gallery and Piazza Populorum and surrounding sites. The staff was helpful and professional, made this first-time trip for visitors with no Italian easy and fun. Our accommodations were good, always clean and secure. we were very happy with our choice of Hotel Twentyone. The breakfasts were fabulous. HIghly recommend.
Patrick, us4 night trip with friends
Twentyone Hotel, Rome
Every thing is perfect and wonderful
Suaad, us5 night family trip
Twentyone Hotel, Rome
The service poor
A Traveler, us2 night trip with friends

See all reviews

Twentyone Hotel, Rome

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