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21c Museum Hotel Louisville, Louisville

4.5-star4.5 stars
700 W Main StreetLouisvilleKY40202United States of America

Luxury hotel with restaurant, near Muhammad Ali Center
  • Free WiFi
  • Excellent Food
Bar and Beverages
Bar is awesome
Awesome vibe
Delicious food
Ordinary amenities
170See all 170 reviews
From 1,399 reviewsTripAdvisor Traveller Rating

21c Museum Hotel Louisville, Louisville

from $199
  • Standard Room, Non Smoking

About 21c Museum Hotel Louisville, Louisville

This hotel is in downtown Louisville, on the city’s Museum Row, across from the Louisville Science Center and the Kentucky Museum of Art and Craft. The Louisville Slugger Museum and the Kentucky Center for the Performing Arts are a block away, and the Muhammed Ali Center is three blocks away.

Hotel Features.
21c Museum Hotel Louisville features an on-site contemporary art museum, specializing in art from the 21st century. The hotel’s building is comprised of former 19th-century tobacco and bourbon warehouses. This hotel, decorated throughout with original art, features an on-site restaurant and bar, offering room service and dishes made with locally sourced ingredients. The business center is open 24 hours a day, and the hotel offers complimentary newspapers and wireless Internet access. Valet parking and a limo/town car service are available for a fee. In addition to yoga classes and complimentary bikes, the hotel offers a spa area providing massage, a sauna and steam room, and fitness equipment. Tour assistance and dry cleaning are available at this smoke-free hotel. The gift shop sells art-influenced clothing, accessories, books, and gifts.

Guestrooms at 21c Museum Hotel Louisville feature original art, turndown service with chocolates, and beds with triple sheeting and down comforters (bedspreads). Desks have ergonomic Herman Miller chairs. Wireless Internet access and newspapers are complimentary, and 42-inch LCD TVs come with premium cable channels and free movie channels. iPod docking stations can be found in each room. In-room safes accommodate laptops. Bottled water is complimentary, and guestrooms provide minibars. Bathrooms include hair dryers and bathrobes.

At a glance

Key facts

Hotel size

  • This hotel has 91 rooms
  • This hotel is arranged over 4 floors


  • Check-in time 4 PM-midnight
  • Check-out time is 11 AM

Required at check in

  • Credit card deposit required

  • Government-issued photo ID required

  • Minimum check-in age is 21

Travelling with others


  • Pets allowed *

  • Up to 50 lb


  • Free WiFi and wired Internet access in public areas

  • Free WiFi and wired Internet access in rooms



  • Valet parking *

Other information

  • Smoke-free property
* See small print for additional details or extra charges

In the hotel

Food and drink
  • Full breakfast daily (surcharge)
  • Restaurant
  • Bar/lounge
  • Room service (during limited hours)
  • Coffee/tea in a common area
Things to do
  • Fitness facilities
  • Spa services on site
  • Spa treatment room(s)
  • Yoga classes/instruction on site
  • Golfing nearby
  • Hiking/biking trails nearby
  • Steam room
  • Sauna
Working away
  • 24-hour business center
  • Conference space
  • Meeting rooms 6
  • Conference space size (feet) - 5000
  • Conference space size (meters) - 465
  • Computer station
  • 24-hour front desk
  • Concierge services
  • Tours/ticket assistance
  • Limo or Town Car service available
  • Dry cleaning/laundry service
  • Free newspapers in lobby
  • Luggage storage
  • Multilingual staff
  • Porter/bellhop
  • Number of buildings/towers - 1
  • Year Built 2006
  • Elevator/lift
  • ATM/banking
  • Safe-deposit box at front desk
  • Accessible bathroom
  • In-room accessibility
  • Roll-in shower

In the room

Home comforts
  • In-room climate control (air conditioning)
  • Air conditioning
  • Minibar
  • Espresso maker
  • Bathrobes
  • Iron/ironing board
Sleep well
  • Hypo-allergenic bedding available
  • Down comforter
  • Blackout drapes/curtains
  • Turndown service
  • Premium bedding
Things to enjoy
  • In-room massage available
Freshen up
  • Designer toiletries
  • Hair dryer
Be entertained
  • 42-inch LCD TV
  • Premium TV channels
  • IPod docking station
Stay connected
  • Desk
  • Free newspaper
  • Free WiFi
  • Free local calls
Food and drink
  • Refrigerator (on request)
  • Free bottled water
  • Daily housekeeping
  • In-room safe (laptop compatible)
  • Connecting/adjoining rooms available

Special features


The spa at 21c Museum Hotel offers massages in 2 treatment rooms; advanced reservations are required.


Proof on Main - This fine-dining restaurant serves breakfast, brunch, lunch, and dinner. Guests can enjoy drinks at the bar.

Awards and affiliations

  • 21c Museum Hotel Louisville is listed in the 2014 Condé Nast Traveler Gold List of the world's best places to stay and the 2015 Travel + Leisure 500.

21c Museum Hotel Louisville, Louisville’s small print

Also known as

  • 21c Hotel Louisville
  • Museum Hotel 21c
  • 21c Hotel Museum
  • 21c Louisville Hotel
  • 21c Museum
  • 21c Museum Hotel
  • 21c Museum Hotel Louisville
  • 21c Museum Louisville
  • Louisville 21c Hotel
  • Louisville 21c Museum


The property has connecting/adjoining rooms, which are subject to availability and can be requested by contacting the property using the number on the booking confirmation.

Reservations are required for massage services and can be made by contacting the property before arrival at the number on the booking confirmation.

Optional extras

Valet parking costs USD 29.00 per night with in/out privileges

Extended parking costs USD 13 per night

Rollaway beds are available for USD 30 per night

Breakfast costs between USD 5 and USD 25 per person (approximately)

Pets are allowed for an extra charge of USD 75.00 per accommodation, per stay

We have included all charges provided to us by this hotel. However, charges can vary, for example, based on length of stay or the room you book.

What’s around 21c Museum Hotel Louisville, Louisville


  • In Downtown Louisville
  • Muhammad Ali Center - 3 min walk
  • Louisville Slugger Museum - 2 min walk
  • Riverfront Plaza Belvedere - 5 min walk
  • KFC Yum Center - 9 min walk
  • Kentucky Museum of Art and Craft - 0 min walk
  • Louisville Science Center - 1 min walk
  • Kentucky Center for the Performing Arts - 2 min walk

Getting around

  • Louisville, KY (SDF-Louisville Intl.) - 13 min drive
  • Valet parking (surcharge)
  • Extended parking (surcharge)

Recent reviews

Exceptional 9.4 From 170 reviews

21c Museum Hotel Louisville, Louisville
Nice Downtown Hotel
We had an issue during check-in at another local new hotel and wound up here. The area and atmosphere is great. If you can't find something to do in the downtown area, you live in a hole.
Maurice, us1 night trip
21c Museum Hotel Louisville, Louisville
Very Good8.0
We had a few glitches with our stay, but the front desk changed our room after we found our room occupied by hotel engineers and our room keys stopped working after the first day. The hotel staff was great and quickly solved our relatively minor problems. The hotel restaurant has good food and there is lots do to in the immediate area.
Julie, us2 night trip
21c Museum Hotel Louisville, Louisville
Provides the "wow" factor for a nice weekend with your S/O
A Traveler, us1 night trip
21c Museum Hotel Louisville, Louisville
We will be back again...
We’ve stayed at 21C several times and it’s enjoyable every time. The museum portion is nice to view art and entertaining. The location is great.
Brad, us1 night trip
21c Museum Hotel Louisville, Louisville
Loved this hotel! Very hip! Great service.
Victoria, us1 night trip

See all reviews

21c Museum Hotel Louisville, Louisville

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