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21c Museum Hotel Louisville, Louisville

4.5-star4.5 stars
700 W Main StreetLouisvilleKY40202United States of AmericaGreat location! See map

Luxury hotel with restaurant, near Muhammad Ali Center
  • Free WiFi
Awesome vibe
Bar and Beverages
Bar is awesome
Delicious food
Value for money
Value for money could be better
179See all 179 reviews
From 1,433 reviewsTripAdvisor Traveller Rating

21c Museum Hotel Louisville, Louisville

from $239
  • Standard Room, Non Smoking

At a glance

Key facts

Hotel size

  • This hotel has 91 rooms
  • This hotel is arranged over 4 floors


  • Check-in time 4 PM-midnight
  • Check-out time is 11 AM

Required at check in

  • Credit card deposit required

  • Government-issued photo ID required

  • Minimum check-in age is 21

Travelling with others


  • Pets allowed *

  • Up to 50 lb


  • Free WiFi and wired Internet access in public areas

  • Free WiFi and wired Internet access in rooms



  • Valet parking *

Other information

  • Smoke-free property
* See small print for additional details or extra charges

In the hotel

Food and drink
  • Full breakfast daily (surcharge)
  • Restaurant
  • Bar/lounge
  • Room service (during limited hours)
  • Coffee/tea in a common area
Things to do
  • Fitness facilities
  • Spa services on site
  • Spa treatment room(s)
  • Yoga classes/instruction on site
  • Golfing nearby
  • Hiking/biking trails nearby
  • Steam room
  • Sauna
Working away
  • 24-hour business center
  • Conference space
  • Meeting rooms 6
  • Conference space size (feet) - 5000
  • Conference space size (meters) - 465
  • Computer station
  • 24-hour front desk
  • Concierge services
  • Tours/ticket assistance
  • Limo or Town Car service available
  • Dry cleaning/laundry service
  • Free newspapers in lobby
  • Luggage storage
  • Multilingual staff
  • Porter/bellhop
  • Number of buildings/towers - 1
  • Year Built 2006
  • Elevator/lift
  • ATM/banking
  • Safe-deposit box at front desk
  • Accessible bathroom
  • In-room accessibility
  • Roll-in shower

In the room

Home comforts
  • In-room climate control (air conditioning)
  • Air conditioning
  • Minibar
  • Espresso maker
  • Bathrobes
  • Iron/ironing board
Sleep well
  • Hypo-allergenic bedding available
  • Down comforter
  • Blackout drapes/curtains
  • Turndown service
  • Premium bedding
Things to enjoy
  • In-room massage available
Freshen up
  • Designer toiletries
  • Hair dryer
Be entertained
  • 42-inch LCD TV
  • Premium TV channels
  • IPod docking station
Stay connected
  • Desk
  • Free newspaper
  • Free WiFi
  • Free local calls
Food and drink
  • Refrigerator (on request)
  • Free bottled water
  • Daily housekeeping
  • In-room safe (laptop compatible)
  • Connecting/adjoining rooms available

Special features


The spa at 21c Museum Hotel offers massages in 2 treatment rooms; advanced reservations are required.


Proof on Main - This restaurant serves breakfast, brunch, lunch, and dinner. Guests can enjoy drinks at the bar.

Awards and affiliations

  • 21c Museum Hotel Louisville is listed in the 2014 Condé Nast Traveler Gold List of the world's best places to stay and the 2015 Travel + Leisure 500.

21c Museum Hotel Louisville, Louisville’s small print

Also known as

  • 21c Hotel Louisville
  • Museum Hotel 21c
  • 21c Hotel Museum
  • 21c Louisville Hotel
  • 21c Museum
  • 21c Museum Hotel
  • 21c Museum Hotel Louisville
  • 21c Museum Louisville
  • Louisville 21c Hotel
  • Louisville 21c Museum


The property has connecting/adjoining rooms, which are subject to availability and can be requested by contacting the property using the number on the booking confirmation.

Reservations are required for massage services and can be made by contacting the property before arrival at the number on the booking confirmation.

Optional extras

Valet parking costs USD 29.00 per night with in/out privileges

Extended parking costs USD 13 per night

Rollaway beds are available for USD 30 per night

Breakfast costs between USD 5 and USD 25 per person (approximately)

Pets are allowed for an extra charge of USD 75.00 per accommodation, per stay

We have included all charges provided to us by this hotel. However, charges can vary, for example, based on length of stay or the room you book.

What’s around 21c Museum Hotel Louisville, Louisville


  • In Downtown Louisville
  • Muhammad Ali Center - 3 min walk
  • Louisville Slugger Museum - 2 min walk
  • Riverfront Plaza Belvedere - 5 min walk
  • KFC Yum Center - 9 min walk
  • Kentucky Museum of Art and Craft - 0 min walk
  • Louisville Science Center - 1 min walk
  • Kentucky Center for the Performing Arts - 2 min walk

Getting around

  • Louisville, KY (SDF-Louisville Intl.) - 13 min drive
  • Valet parking (surcharge)
  • Extended parking (surcharge)

Recent reviews

Exceptional 9.4 From 179 reviews

21c Museum Hotel Louisville, Louisville
Bourbon Trail weekend
My husband, father, brother and brothers-in-law stayed there when they were on the Bourbon Trail. They especially loved the bartender. She really knew her bourbon!
Margaret, us4 night trip
21c Museum Hotel Louisville, Louisville
Hip and chic
The hotel was beautiful and the service was stellar. The room was really spacious with comfortable linen and lovely toiletries and soft towels. Loved our stay. Don’t know if it would be easy for a child.
Tareyece, us1 night trip
21c Museum Hotel Louisville, Louisville
Funky Hotel
Very funky hotel, lots of visual entertainment. Definitely not a place for little kids. Very good bar and restaurant attached.
A Traveler, us2 night trip
21c Museum Hotel Louisville, Louisville
21C a unique experience.
21c continues to be a unique experience of the highest quality.
Eric, us2 night trip
21c Museum Hotel Louisville, Louisville
bad check in
I booked room around 1am thinking I could check in once I got to Louisville, around 2 or 2:30 called to make sure they said had to check in after 4. tried to cancale they said I couldn't . so that was a wast of money cause I found a room aloft downtown Louisville was just fine
A Traveler, us1 night trip

See all reviews

21c Museum Hotel Louisville, Louisville

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