Hotels in Santa Fe, Panama

Search & Compare Santa Fe Hotels

Get Secret Prices on select hotels

These prices aren’t available to everyone.

  • Pay now or later on most rooms
  • Free cancellation on most rooms
  • Price Guarantee

Best hotels in Santa Fe

Santa Fe overview

Santa Fe is a friendly locale known for its countryside and gardens, and surrounded by picturesque views of waterfalls and mountains. You'll enjoy the ample coffee and dining options, along with outdoor areas for horseback riding and hiking. Visitors can plan a fun excursion to Alto de Piedra Waterfall. Local sights like Cascada de Bermejo and Cerro Tute are worth a visit. If you're looking for a family-friendly getaway, Santa Fe is for you.

Where to stay in Santa Fe

Whether you're planning to stay for a night or for the week, the area around Santa Fe has accommodations to fit every need. Search for hotels in Santa Fe with Hotels.com by checking our online map. Our maps display the areas and neighborhoods around all Santa Fe hotels so you can see how close you are from landmarks and attractions, and then refine your search within the larger area. The best Santa Fe hotel deals are here with our lowest price guarantee.

How to get to Santa Fe

Fly in to Panama City (PAC-Marcos A. Gelabert Intl.), 109.3 mi (176 km) from downtown Santa Fe. Panama City (PTY-Tocumen Intl.) is the next closest major airport, 122.6 mi (197.3 km) away.

What to see around Santa Fe

Some recommended places to see include:
  • • Cascada de Bermejo
  • • Cerro Tute
  • • Quebrada Bulava
  • • Mercado
  • • Catholic Church of Santa Fe

When to visit Santa Fe

If you're still deciding when to visit, here are the seasonal norms to help you plan:

Seasonal temperature averages
  • January-March: 94°F day, 67°F night
  • April-June: 94°F day, 71°F night
  • July-September: 88°F day, 70°F night
  • October-December: 89°F day, 68°F night
Seasonal rainfall averages
  • January-March: 7.95 inches
  • April-June: 32.52 inches
  • July-September: 39.25 inches
  • October-December: 33.03 inches
  • Dining
  • Family