Skip to main content.

Hotels in Santa Isabel, Panama

Search & Compare Santa Isabel Hotels

Save more with Secret Prices

Get instant savings with Secret Prices

  • Pay now or later on most rooms
  • Free cancellation on most rooms
  • Price Guarantee

Best hotels in Santa Isabel

What's Santa Isabel Like?

If you're looking for a place to get away, look no further than Santa Isabel. Whether you're planning to stay for a night or for the week, the area around Santa Isabel has accommodations to fit every need. Search for hotels in Santa Isabel with Hotels.com by checking our online map. Our map displays the areas and neighborhoods around all Santa Isabel hotels so you can see how close you are from landmarks and attractions, and then refine your search within the larger area. The best Santa Isabel hotel deals are here with our lowest price guarantee.

Where are the Best Places to Stay in Santa Isabel?

Below are the number of accommodations by star rating in Santa Isabel and the surrounding area:

  • • 13 3-star accommodations from USD 90 per night

When Is the Best Time to Visit Santa Isabel?

  • • Hottest months: April, March, May, February (average 91°F)
  • • Coldest months: January, February, December, March (average 73°F)
  • • Rainiest months: November, October, June, and December (average 0.34 inches of rainfall)