If you're looking for a place to get away, look no further than Cayo Largo. Whether you're planning to stay for a night or for the week, the area around Cayo Largo has accommodations to fit every need. Search for hotels in Cayo Largo with Hotels.com by checking our online map. Our map displays the areas and neighborhoods around all Cayo Largo hotels so you can see how close you are from landmarks and attractions, and then refine your search within the larger area. The best Cayo Largo hotel deals are here with our lowest price guarantee.