Hotels in Santo Antonio, Sao Tome and Principe

Search & Compare Santo Antonio Hotels

Get Secret Prices on select hotels

These prices aren’t available to everyone.

Pay now or later on most rooms

Free cancellation on most rooms

Price Guarantee

Best hotels in Santo Antonio

With hotels.com we help you find the best hotels in Santo Antonio, Sao Tome and Principe.

You can compare all of our Santo Antonio hotel rooms including the major Santo Antonio hotel chains using our genuine Hotels.com guest reviews as well as TripAdvisor Santo Antonio hotel reviews to help find the perfect hotel room when booking your accommodation in Santo Antonio. We also feature Expedia Santo Antonio hotels and reviews.

When you book your Santo Antonio stay with Hotels.com you may also earn free nights on participating hotels by joining the Hotels.com Welcome Rewards program. It's free to join and only takes 2 minutes to sign up and when you stay 10 nights you receive 1 night free*. So even a short weekend break in Santo Antonio can get you on your way to a free night.

Why use Hotels.com to book your Santo Antonio lodging & accommodation?

We can help you to find the perfect Santo Antonio hotel room for almost any occaision. With our fast and secure hotel search you may compare different Santo Antonio hotels by:

  • - Price
  • - Location within Santo Antonio
  • - Neighborhoods in Santo Antonio
  • - Nearby Santo Antonio attractions
  • - Hotels in different areas of Sao Tome and Principe
  • - Genuine Hotels.com guest reviews for Santo Antonio
  • - Star rating
  • - Amenities
  • - Hotel name & chain
  • - Theme


For every hotel in Santo Antonio Sao Tome and Principe we provide:

  • - Up to the minute hotel rates & availability
  • - In depth hotel information and photos
  • - Detailed Santo Antonio maps showing the locations of your hotel in Santo Antonio and the nearest transport and landmarks
  • - TripAdvisor Santo Antonio hotel review score


And when you make a hotel reservation in Santo Antonio with Hotels.com we'll send you email and text confirmations with the reservation details of your Santo Antonio hotel booking along with contact details, directions, information on nearby Santo Antonio attractions, restaurants and even the weather - and if you get stuck, we're only a phone call away.

To make the most of our service, download our mobile & tablet apps and sign up to our newsletter or follow us on Facebook, Google+ or Twitter to receive the latest deals and Hotels.com Santo Antonio discount codes.