Properties are selected based on real traveler reviews and popularity among guests who’ve booked a night near Historic Main Street on Hotels.com. These 4 Star Hotels close to Historic Main Street consistently deliver on quality, location and traveler experience. Last updated on .
4 Star Hotels near Historic Main Street
Free cancellation options if plans change
Unlock travel rewards with One Key
Save more with Member Prices
Check prices for these dates
4 Star Hotels near Historic Main Street
8.6 out of 10, Excellent, (1,052 reviews)
$175 nightly
The price is $205
Sep 22 - Sep 23
Total with taxes and fees
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Discover Historic Main Street's neighborhood and other top neighborhoods in St. Charles
St. Charles Historic District
Discover a national historic district featuring over 100 buildings, including the First Missouri State Capitol and St. Charles Odd Fellows Hall, showcasing architectural styles like Greek Revival and Italianate.
Riverport
Maryland Heights's Riverport neighborhood has a host of places to visit such as Centene Community Ice Center and Hollywood Casino.
Top landmarks in Historic Main Street
Keep exploring
- Hotels in Hazelwood
- Hotels near Family Arena
- Hotels in Chesterfield
- Family Friendly in St. Charles
- 4 Star Hotels in Littles Island
- 4 Star Hotels in Watkins Island
- St. Charles Historic District Hotels
- Hotels in Town and Country
- Indoor Pool in St. Charles
- Golf in St. Louis
- Hotels in Bridgeton
- Free Breakfast in St. Charles
- Hotels in Brentwood
- Apartments in St. Louis
- Red Roof Inn Hotels in Pelican Island
- Luxury Hotels in Central West End
- 2 Star Hotels in Bridgeton
- 2 Star Hotels in O'Fallon
- NH Hotels in Cora Island
- Melia Hotels in Pelican Island
- 4 Star Hotels in Dresser Island
- Bedandbreakfast in Defiance
- Romantic Hotels in St. Charles Historic District
- 5 Star Hotels in Cora Island
- 5 Star Hotels in Littles Island
- Hotels near Hollywood Casino
- Spa in St. Louis
- Hotels in St. Peters
- Hotels in St. Charles
- Kitchenette in St. Charles
- Hotels near Hollywood Casino Amphitheatre
- Hotels near Historic Main Street
- Safaritentalow in Cora Island
- Pet Friendly in St. Charles
- Hotels in Florissant
- Motel 6 Hotels in Pelican Island
- Hotels in Ferguson
- University City Hotels
- 5 Star Hotels in Pelican Island
- 5 Star Hotels in Maple Island
- Drury Inn & Suites Hotels in Littles Island
- Countryhouse in Pelican Island
- Creve Coeur Hotels
- 3 Star Hotels in St. Charles
- Casino in St. Charles
- Hotels in Frontenac
- Hotels in Earth City
- 5 Star Hotels in St. Louis
- 5 Star Hotels in St. Peters
- 4 Star Hotels in East Island
- Budget in St. Charles
- Aparthotels in Wentzville
- Pool in St. Charles
- Hotels in Maryland Heights
- 4 Star Hotels in Maple Island
- Walt Disney World Hotels in Pelican Island
- 2 Star Hotels in Maryland Heights
- Motels in St. Louis
- 3 Star Hotels in Chesterfield
- 4 Star Hotels in Miller Island
- Hotels in Olivette
- 4 Star Hotels in Washington
- 4 Star Hotels in Cora Island
- Hotels in O'Fallon
- Hotels in Cottleville
- Hotels in Overland
- Inns in Pelican Island
- 4 Star Hotels in St. Louis
- Hotels in St. Ann
- 2 Star Hotels in Hazelwood
- Guesthouses in Maple Island
- La Quinta Inn & Suites Hotels in Pelican Island
- 2 Star Hotels in St. Charles
- Marriott Hotels in Pelican Island
- 3 Star Hotels in Central West End
- 3 Star Hotels in University City
- 4 Star Hotels in McGirk Island
- Steigenberger Hotels in Pelican Island
- Hot Tub in St. Charles
- Cabins in House Springs
- Hotels near Centene Community Ice Center
- 4 Star Hotels in Pelican Island
- Wifi in St. Peters
- 3 Star Hotels in Bridgeton
- 3 Star Hotels in Maryland Heights
- Cottages in St. Charles