Hotels near Downtown San Francisco

When it comes to visiting Downtown San Francisco, your hotel experience affects the memories you make and how you spend your time in California. Whether you are searching for a cheap Downtown San Francisco hotel, a 5-star hotel near Downtown San Francisco or a family-friendly Downtown San Francisco hotel, using Hotels.com can ensure you find the best accommodations for your stay.

Not sure of what to do once you get there? Reading guest reviews will give you a more personal perspective on a fellow traveler's experience during their stay at Downtown San Francisco hotels. By reading about the experiences of other travelers, you can learn more about the hotels’ quality of service, and the best things to do around San Francisco. There are several hotels in San Francisco that offer a variety of amenities.

Here's a quick overview of what our verified guests have rated as the best Downtown San Francisco hotels for:

• Cleanliness: The St. Regis San Francisco
• Service: Inn At Union Square - A Greystone Hotel
• Comfort: The St. Regis San Francisco
• Condition: The St. Regis San Francisco

Be sure to download the Hotels.com app so you can book your reservations on the go and save hotels to view and compare later. Use our search feature and map to compare locations, prices, and the hotel amenities for your Downtown San Francisco hotel reservations. Join our Welcome Rewards Program for a chance to win a free night at one of our Downtown San Francisco hotels.