Business Hotels in Panama City

Free cancellation options if plans change

Unlock travel rewards with One Key

Save more with Member Prices

Check prices for these dates

Tonight

Tomorrow

Next weekend

In two weeks

Business Hotels in Panama City

Hilton Garden Inn Panama City Airport

Panama City

$115 nightly

Sep 7 - Sep 8

Total with taxes and fees

See more properties

Top neighborhoods in Panama City

A flagpole with the American flag, palm trees, and a sign that reads "Panama City Marina".

Downtown Panama City

Downtown Panama City balances historic charm with waterfront beauty along St. Andrews Bay. The Victorian-era McKenzie House and brick-faced Martin Theatre showcase the area's rich past. Stroll along waterfront promenades where pelicans dive and sailboats bob in emerald waters, or catch rotating exhibitions at the Panama City Center for the Arts. Waterfront seafood restaurants serve fresh Gulf shrimp and grouper with bay views. Boutique hotels in restored buildings and historic bed & breakfasts offer personalized stays with period furnishings. The compact downtown core is easily walkable with brick sidewalks connecting attractions, shops, and the marina.

See properties

A dolphin jumping out of the water with a boat in the background.

St Andrews

St. Andrews blends coastal charm with maritime history along Panama City's bayfront. The historic district's Victorian buildings and the restored 1913 Panama City Publishing Company Museum showcase the neighborhood's rich heritage. Stroll waterfront paths with Gulf Coast views, browse the farmers market for local seafood, or watch boats bobbing in St. Andrews Marina. Fresh Gulf seafood stars at casual waterfront restaurants where you can enjoy grouper sandwiches with bay views. Boutique inns and historic bed & breakfasts in restored Victorian homes offer personalized service. The walkable core connects the marina, shops, and tree-lined streets, making it perfect for leisurely exploration.

See properties

A coastal landscape with a beach, clear turquoise waters, and a distant city skyline.

Bay VIew Addition

Bay View Addition gives you a peaceful escape from Panama City's tourist crowds while keeping you close to the action. Scenic streets lead to St. Andrews Bay, where calm waters invite fishing and kayaking adventures. Mature oak trees create natural canopies over residential roads, offering glimpses of waterfront views and quiet places to unwind. Accommodations range from budget-friendly vacation rentals to modest bed & breakfasts, all at prices that won't break the bank. Though dining options are limited within the neighborhood, you're just a short drive from Panama City's restaurants. A car is recommended since public transit is minimal, but the trade-off is authentic local charm.

See properties

A building with a sign reading "MacArthur Ave" and "Emergency and Trauma Center" on the side.

Bunkers Cove

Bunkers Cove gives you a front-row seat to St. Andrews Bay without the tourist chaos. This upscale residential area lets you live like a well-heeled local with waterfront views and peaceful streets perfect for evening strolls. When you're ready to explore, the Cove Shopping Center, Visual Arts Center, and Martin Theatre are just minutes away. Getting around requires wheels—bring your car or budget for rideshares to reach Panama City's restaurants and attractions. Accommodation here means luxury vacation rentals with private docks and bay access rather than hotels. The payoff? Quiet mornings watching boats drift by and the perfect launch spot for kayaking adventures.

See properties

A white sandy beach with clear turquoise water, a pier, and a city skyline in the distance.

Gulf Coast Development

Gulf Coast Development in Panama City delivers the Florida beach dream without the fuss. White sand beaches invite you to soak up the sun while resort pools offer a refreshing break. Nearby attractions like Panama City Marina and St. Andrews State Park keep your days filled with coastal adventures. Water sports rentals and fishing charters satisfy your thrill-seeking side. Dining options range from casual beachfront spots to upscale hotel restaurants serving fresh Gulf seafood. Most accommodations feature oceanfront views with modern amenities and direct beach access. Rental cars are your best bet for exploring beyond the resort area, though walkability is good within each hotel zone.

See properties

Top landmarks in Panama City

A marina with several boats docked, a pier extending into the water, and palm trees along the shore.

Panama City Marina

8.4/10 (468 reviews)

You can stroll along Panama City Marina for relaxing water views when you're in Downtown Panama City. Hotels.com travelers also say the area is family-friendly and has lots of nice beaches.

See properties

A building with a mural, a modern structure with large windows, and a parking lot with landscaping.

Visual Arts Center of Northwest Florida

8.4/10 (6 reviews)

Why not give yourself a treat with a trip to Visual Arts Center of Northwest Florida, just one of the family attractions in central Panama City. Why not take a stroll along the beaches and watch the sunset while you're here? If you have fun at Visual Arts Center of Northwest Florida, you'll love Panama City Center for the Arts, just a short walk away.

See properties

Frequently asked questions

What are the best business hotels in Panama City?

Based on guest reviews, Courtyard by Marriott Panama City is one of the top business hotels in Panama City. Take advantage of a 24-hour front desk and meeting rooms here. Fairfield Inn & Suites by Marriott Panama City Beach is also designed with corporate travelers in mind. It's another visitor favorite.

What are the cheapest business hotels in Panama City?

Take your pick of affordable Panama City business hotels from $67 that work with your budget. Check out Fairfield Inn & Suites by Marriott Panama City Beach, which features a 24-hour front desk and a free breakfast. Another smart pick for professionals on a budget is Seychelles Beach Resort By Vacasa.

What is the best time to stay in a business hotel in Panama City?

If you'd like to visit when it's less busy, book your work trip for November. You could score some great deals on business hotels in Panama City around then. The warmest conditions are in June, with temperatures ranging from 77ºF (25ºC) to 88ºF (31ºC). It's usually coolest in January, averaging between 48ºF (9ºC) and 61ºF (16ºC).

What are the closest business hotels to Panama City Mall?

Stay in a business hotel in Panama City and then explore the sights once your workday is over. Just a short drive from Panama City Mall, Courtyard by Marriott Panama City is a great option. It comes with a swimming pool and designer toiletries. Hilton Garden Inn Panama City is another business-friendly property near this top attraction.

What business hotels in Panama City have a pool?

With a pool, designer toiletries and pool sun loungers, Courtyard by Marriott Panama City is where you can mix business with leisure. Or, treat yourself to some downtime after a demanding day at Fairfield Inn & Suites by Marriott Panama City Beach. This Panama City business hotel comes with a pool too.

Are there any business hotels in Panama City with parking?

There are 15,492 Panama City business hotels with parking to pick from. Reserve a room at Courtyard by Marriott Panama City, which comes with meeting rooms, a 24-hour front desk and room for your ride. Fairfield Inn & Suites by Marriott Panama City Beach is another option with parking.

Are all taxes and fees included in the Panama City hotel prices shown on Hotels.com?

Hotels.com provide upfront pricing so you can relax knowing you won't be met with surprise additional fees or taxes when you're ready to confirm your booking. From the time you start your search on Hotels.com, the price you see is what you pay. This makes it much easier to compare properties and secure our best deal for your next getaway.

Keep exploring

Lodging