Hotels in Cairo, Illinois

Search & Compare Cairo Hotels

  • Pay now or later on most rooms
  • Free cancellation on most rooms
  • Price Guarantee

Best hotels in Cairo

Cairo overview

Cairo is a friendly locale distinct for its historical sites and riverfront, and known for its ruins and library. You're sure to appreciate the ample beer and dining options. Learn about local heritage at landmarks like Fort Defiance and Columbus-Belmont State Park. Local sights like Mound City National Cemetery and Ballard Wildlife Management Area are worth a visit. A family- and business-friendly area, Cairo also has something for everyone.

Where to stay in Cairo

Whether you're planning to stay for a night or for the week, the area around Cairo has accommodations to fit every need. Search for hotels in Cairo with Hotels.com by checking our online map. Our maps display the areas and neighborhoods around all Cairo hotels so you can see how close you are from landmarks and attractions, and then refine your search within the larger area. The best Cairo hotel deals are here with our lowest price guarantee.

How to get to Cairo

Fly in to Cape Girardeau, MO (CGI-Cape Girardeau Municipal), 23.7 mi (38.1 km) from downtown Cairo. Paducah, KY (PAH-Barkley Regional) is the next closest major airport, 24.1 mi (38.8 km) away.

What to see around Cairo

Memorable for its historical sites, ruins, and these top landmarks to visit:
  • • Fort Defiance
  • • Columbus-Belmont State Park
Here are some favorite choices:
  • • Mound City National Cemetery
  • • Ballard Wildlife Management Area
  • • Ullin City Hall

When to visit Cairo

Wondering when's the best time to visit? Here are seasonal norms to help you plan your trip:

Seasonal temperature averages
  • January-March: 64°F day, 25°F night
  • April-June: 89°F day, 41°F night
  • July-September: 89°F day, 53°F night
  • October-December: 75°F day, 26°F night
Seasonal rainfall averages
  • January-March: 11.65 inches
  • April-June: 13.82 inches
  • July-September: 10.31 inches
  • October-December: 12.99 inches