Hotels in Cairo, Illinois

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Best hotels in Cairo

Cairo overview

If you're looking for a new favorite getaway, look no further than Cairo. You can learn about the local heritage of Cairo at landmarks like Fort Defiance.

Where to stay in Cairo

Whether you're planning to stay for a night or a week, Cairo has accommodations to fit your needs. You can shop as many as 179 deals for Cairo accommodations on, some with discounts of up to 15%. We have room prices as low as 48 USD per night and here you'll find a breakdown of hotels by star rating in Cairo as well as in the surrounding area:
  • • 7 3-star hotels from 63 USD per night
  • • 7 2-star hotels from 48 USD per night

How to get to Cairo

Fly into Cape Girardeau, MO (CGI-Cape Girardeau Municipal), 23.7 mi (38.1 km) from the heart of Cairo. Paducah, KY (PAH-Barkley Regional) is the next closest major airport, 24.1 mi (38.8 km) away.

What to see around Cairo

Memorable for its historical sites, ruins, and these top landmarks to visit:
  • • Fort Defiance
  • • Columbus-Belmont State Park
Here are some favorite choices:
  • • Mound City National Cemetery
  • • Ballard Wildlife Management Area
  • • Ullin City Hall

When to visit Cairo

Wondering what time of year to travel or what clothes to pack? Here are some typical temperatures so you'll know what to expect for your trip:

Seasonal temperature averages
  • • January-March: 64°F day, 25°F night
  • • April-June: 89°F day, 41°F night
  • • July-September: 89°F day, 53°F night
  • • October-December: 75°F day, 26°F night
Seasonal rainfall averages
  • • January-March: 11.65 inches
  • • April-June: 13.82 inches
  • • July-September: 10.31 inches
  • • October-December: 12.99 inches