Skip to main content.

Hotels in Mayo, Florida

Search & Compare Mayo Hotels

Save more with Secret Prices

Get instant savings with Secret Prices

  • Pay now or later on most rooms
  • Free cancellation on most rooms
  • Price Guarantee

Best hotels in Mayo

What's Mayo Like?

If you're looking to discover somewhere new, look no further than Mayo. Whether you're planning to stay for a night or for the week, the area around Mayo has accommodations to fit every need. Search for hotels in Mayo with Hotels.com by checking our online map. Our map displays the areas and neighborhoods around all Mayo hotels so you can see how close you are from landmarks and attractions, and then refine your search within the larger area. The best Mayo hotel deals are here with our lowest price guarantee.

Where are the Best Places to Stay in Mayo?

Below are the number of accommodations by star rating in Mayo and the surrounding area:

  • • 3 3-star accommodations from USD 96 per night
  • • 5 2-star accommodations from USD 46 per night

When Is the Best Time to Visit Mayo?

  • • Hottest months: July, August, June, September (average 93°F)
  • • Coldest months: January, December, February, March (average 43°F)
  • • Rainiest months: June, July, August, and March (average 5.95 inches of rainfall)