Hotels in Mission, South Dakota

Search & Compare Mission Hotels

Get Secret Prices on select hotels

These prices aren’t available to everyone.

Pay now or later on most rooms

Free cancellation on most rooms

Price Guarantee

Best hotels in Mission

How to Find the Best Mission hotels with Hotels.com

Located along the Mexico border and an easy day trip from the ocean, you'll discover a unique, diverse, and unforgettable travel destination in Mission, Texas! No matter who you are or how you like to get away, there's something waiting for you in Mission, and a hotel to suit all your unique travel needs. At Hotels.com, we're ready to offer you our industry-leading services, regional experts, and unbeatable hotel selection along with step-by-step guidance to ensure that your Mission trip is the very best it can be! When you book with Hotels.com, you can browse online at your leisure through dozens of amazing Mission hotels, book over the phone hassle-free, or speak to one of our travel assistants who will help you find those perfect accommodations. We take all the guesswork out of your trip, and you can even read through thousands of reviews by real Hotels.com users so you'll know exactly what to expect from your hotel. So what are you waiting for? Hop online or call us up today to start planning your amazing trip to Mission!

What's Mission like?

Mission has something for every visitor and every getaway, no matter why you travel! For nature-lovers or families traveling with kids, hotels near the National Butterfly Center are sure to please! Other natural and animal-centric activities include the World Birding Center, the Bentsen-Rio Grande Valley State Park, and lots of hiking and trails to take in the natural beauty of the region. Take a cruise on the Riverside Dreamer River Tours to take in the sights from another vantage point! For history-buffs, Mission has a lot to offer with its rich history and preserved buildings. Explore La Lomita Mission for one of the city's most significant historical attractions. Relax with your favorite hobby by discovering accommodations by the Shary Municipal Golf Course or the many other scenic courses in the area. No matter what, you'll find lots of activities just around the corner from any of the wonderful Mission hotels, all framed by the luscious scenery and friendly faces of the city.

Tips for Getting Along with Locals in Mission

No matter how you like to get away, you know that embarking with some travel tips from the locals can make a huge difference during your vacation! Fortunately, we at Hotels.com have already done the work for you. Thanks to our regional experts, you'll have access to the "inside scoop" on Mission and how to best get along with and blend in with the locals. First, when you arrive you will notice the amazing cultural diversity right off the bat. Embark with an open mind and broad horizons, and be ready to try new things! You'll find that the history of the region is also fascinating and very important to many locals, so it's always a good idea to read up a bit on the area and its history (particularly the attractions you want to visit). A little know-how will go a long way to showing the locals you care, and they're sure to respond positively. Otherwise, you will find residents to be very friendly and open towards visitors, and they'll generally be very happy to give you directions or a restaurant suggestion. Speaking of which, don't forget to try all the region's amazing cuisine, and you'll find Mexican, American, and other amazing eateries just steps from many Mission hotels!