Business Hotels in San Diego

  • Pay now or later on most rooms
  • Free cancellation on most rooms
  • Price Guarantee

Collect 10 nights get 1 free*

And look out for Secret Prices on select hotels

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Picture of La Quinta Inn & Suites San Diego Old Town/Airport in San Diego

La Quinta Inn & Suites San Diego Old Town/Airport

(3.0 miles to city center)
  • 2.5 stars
Good 3.9 / 5
from
$139
Picture of Humphreys Half Moon Inn in San Diego

Humphreys Half Moon Inn

(3.6 miles to city center)
  • 3.5 stars
Excellent 4.2 / 5
from$260
$169
Picture of The Lafayette Hotel, Swim Club & Bungalows in San Diego

The Lafayette Hotel, Swim Club & Bungalows

(3.1 miles to city center)
  • 3.5 stars
Excellent 4.1 / 5
from$175
$158
Picture of Ramada Gaslamp Convention Center-The Historic St James Hotel in San Diego

Ramada Gaslamp Convention Center-The Historic St James Hotel

(320 yards to city center)
  • 3 stars
Good 3.6 / 5
from
$149
Picture of Cabrillo Inn & Suites in San Diego

Cabrillo Inn & Suites

(4.1 miles to city center)
  • 2 stars
Good 3.1 / 5
from$109
$93
Picture of The Westin San Diego Gaslamp Quarter in San Diego

The Westin San Diego Gaslamp Quarter

(80 yards to city center)
  • 4 stars
Excellent 4.3 / 5
from
$165
Picture of Kona Kai Resort & Spa, A Noble House Resort in San Diego

Kona Kai Resort & Spa, A Noble House Resort

(4.0 miles to city center)
  • 4 stars
Good 3.9 / 5
from
$175
Picture of La Jolla Shores Hotel in La Jolla

La Jolla Shores Hotel

(11 miles to city center)
  • 3 stars
Excellent 4.2 / 5
from
$319
Picture of Red Roof Inn San Diego Downtown in San Diego

Red Roof Inn San Diego Downtown

(800 yards to city center)
  • 2 stars
Good 3.1 / 5
from$109
$93
Picture of Omni San Diego Hotel in San Diego

Omni San Diego Hotel

(950 yards to city center)
  • 4 stars
Excellent 4.5 / 5
from$249
$224
Picture of Renaissance San Diego Hotel in San Diego

Renaissance San Diego Hotel

(600 yards to city center)
  • 4 stars
Good 3.9 / 5
from$199
$195
Picture of Keating Hotel in San Diego

Keating Hotel

(220 yards to city center)
  • 4 stars
Good 3.9 / 5
from
$172
Picture of La Pensione Hotel in San Diego

La Pensione Hotel

(1200 yards to city center)
  • 3 stars
Excellent 4.0 / 5
from$170
$145
Picture of Ayres Lodge Alpine in Alpine

Ayres Lodge Alpine

(24 miles to city center)
  • 2.5 stars
Excellent 4.3 / 5
from
$120
Picture of Wyndham San Diego Bayside in San Diego

Wyndham San Diego Bayside

(1200 yards to city center)
  • 4 stars
Excellent 4.0 / 5
from
$152
Picture of Hercor Hotel - Urban Boutique in Chula Vista

Hercor Hotel - Urban Boutique

(7.1 miles to city center)
  • 3 stars
Excellent 4.0 / 5
from$168
$126
Picture of Best Western Cabrillo Garden Inn in San Diego

Best Western Cabrillo Garden Inn

(770 yards to city center)
  • 2.5 stars
Excellent 4.0 / 5
from$169
$152
Picture of Rancho Valencia Resort and Spa in Rancho Santa Fe

Rancho Valencia Resort and Spa

(19 miles to city center)
  • 5 stars
Outstanding 5.0 / 5
from
$621
Picture of Andaz San Diego in San Diego

Andaz San Diego

(400 yards to city center)
  • 4 stars
Excellent 4.3 / 5
from
$199
Picture of San Diego Marriott La Jolla in La Jolla

San Diego Marriott La Jolla

(11 miles to city center)
  • 4 stars
Excellent 4.1 / 5
from$189
$170
Picture of Manchester Grand Hyatt San Diego in San Diego

Manchester Grand Hyatt San Diego

(740 yards to city center)
  • 4 stars
Outstanding 4.6 / 5
from
$199
Picture of Best Western Plus Marina Gateway Hotel in National City

Best Western Plus Marina Gateway Hotel

(4.9 miles to city center)
  • 3 stars
Excellent 4.4 / 5
from$170
$161
Picture of Bahia Resort Hotel in San Diego

Bahia Resort Hotel

(6.3 miles to city center)
  • 3.5 stars
Excellent 4.2 / 5
from$368
$221
Picture of Gaslamp Plaza Suites in San Diego

Gaslamp Plaza Suites

(260 yards to city center)
  • 3.5 stars
Excellent 4.1 / 5
from
$159
Picture of Pleasant Inn in San Diego

Pleasant Inn

(8.3 miles to city center)
  • 2.5 stars
Excellent 4.1 / 5
from$99
$89

Collect 10 nights get 1 free*

And look out for Secret Prices on select hotels

  1. 1
  2. 2
  3. 3
  4. 4
  5. 5
  6. 6
  7. 7
  8. 8
  9. 9
  10. 10
=
FREE