Hotels in Depew, New York

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Best hotels in Depew

Depew overview

Whatever your interests are, Depew has something for you. Depew might not have well-known attractions within the city, but you won't need to venture far to find top places to visit like Buffalo Museum of Science and Frank Lloyd Wright's Darwin D. Martin House. Popular sights in the surrounding area include Buffalo Zoo and Buffalo and Erie County Botanical Gardens.

Where to stay in Depew

Whether you plan to stay for a night or a week, Depew has the right accommodation for you. You can shop as many as 339 deals for Depew accommodations on, some with discounts of up to 50%. Our room prices start at 29 USD per night and below are the number of hotels by star rating in Depew as well as in the surrounding area:
  • • 26 4-star hotels from 89 USD per night
  • • 91 3-star hotels from 66 USD per night
  • • 61 2-star hotels from 45 USD per night

How to get to Depew

Fly into Buffalo, NY (BUF-Buffalo Niagara Intl.), 2.7 mi (4.3 km) from central Depew. Niagara Falls, NY (IAG-Niagara Falls Intl.) is the next closest major airport, 18.3 mi (29.5 km) away.

What to see around Depew

Outdoor activities are at hand such as adventure tours, sporting events, and fishing, along with attractions like:
  • • Reinstein Woods Nature Preserve and Environmental Education Center
  • • Holiday Twin Rinks
  • • Elegant Builders Raceway Park
  • • Northtown Center at Amherst
  • • Burt Flickinger Athletic Center
Family-friendly attractions include:
  • • Buffalo Zoo
  • • Lasertron
  • • Adventure Landing
  • • Erie Basin Marina Gardens
  • • Hamburg Fairgrounds
It's notable for its hiking trails, flowers, and top spots for nature lovers that include:
  • • Stiglmeier Park
  • • Charles E. Burchfield Nature and Art Center
  • • Island Park
  • • Glen Falls
  • • Hennepin Park
Whether window-shopping or searching for a perfect souvenir, here are some favorite shopping areas:
  • • Walden Galleria Mall
  • • Eastern Hills Mall
  • • Southgate Plaza
  • • Broadway Market
  • • Boulevard Mall
Here are some top sights in the surrounding area:
  • • Buffalo Museum of Science (7 mi/11.3 km from the city center)
  • • Frank Lloyd Wright's Darwin D. Martin House (7.6 mi/12.3 km from the city center)
  • • Buffalo Zoo (7.8 mi/12.6 km from the city center)
  • • Buffalo and Erie County Botanical Gardens (7.8 mi/12.6 km from the city center)
  • • Pierce - Arrow Museum (8.5 mi/13.7 km from the city center)

When to visit Depew

Do you want to know the ideal time of year to visit? Here's a list of the seasonal weather norms to help with trip planning:

Seasonal temperature averages
  • • January-March: 48°F day, 18°F night
  • • April-June: 79°F day, 31°F night
  • • July-September: 80°F day, 48°F night
  • • October-December: 65°F day, 20°F night
Seasonal rainfall averages
  • • January-March: 8.66 inches
  • • April-June: 10.12 inches
  • • July-September: 10.39 inches
  • • October-December: 11.42 inches