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Hotels in De Soto, Missouri

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Best hotels in De Soto

De Soto overview

You'll enjoy the ample dining choices. There's plenty to explore, including local sights like Washington State Park and St. Francois State Park. If you're looking for a family-friendly getaway, De Soto is for you.

Where to stay in De Soto

Whether traveling for business or pleasure, De Soto can comfortably accommodate you. You can shop as many as 28 deals for De Soto accommodations on, some with discounts of up to 30%. We have room prices as low as 50 USD per night and here you'll find a breakdown of hotels by star rating in De Soto as well as in the surrounding area:
  • • 14 3-star hotels from 71 USD per night
  • • 6 2-star hotels from 50 USD per night

How to get to De Soto

Fly in to St. Louis, MO (STL-Lambert-St. Louis Intl.), 44.8 mi (72 km) from downtown De Soto.

What to see around De Soto

Some recommended places to see include:
  • • Washington State Park
  • • St. Francois State Park
  • • Sandy Creek Covered Bridge State Historic Site
  • • Sunridge Park
  • • Persimmon Ridge Winery

When to visit De Soto

Wondering what time of year to travel or what clothes to pack? Here are some average seasonal norms to help you with your planning:

Seasonal temperature averages
  • • January-March: 62°F day, 22°F night
  • • April-June: 87°F day, 39°F night
  • • July-September: 88°F day, 49°F night
  • • October-December: 73°F day, 22°F night
Seasonal rainfall averages
  • • January-March: 8.66 inches
  • • April-June: 13.23 inches
  • • July-September: 11.34 inches
  • • October-December: 11.46 inches