Hotels in De Soto, Missouri

Search & Compare De Soto Hotels

Get Secret Prices on select hotels

These prices aren’t available to everyone.

Pay now or later on most rooms

Free cancellation on most rooms

Price Guarantee

Best hotels in De Soto

De Soto overview

De Soto is a small town unique for its wineries and shops. You're sure to enjoy all of the coffee and bar options. Visitors can plan a fun excursion to Persimmon Ridge Winery. There's plenty to explore, including local sights like Sunridge Park and St. James Catholic Church. If you're looking for a family- and business-friendly getaway, De Soto is for you.

Where to stay in De Soto

Whether traveling for business or pleasure, De Soto can comfortably accommodate all visitors.
  • • 6 2-star hotels with an average price of $51 per night
  • • 12 3-star hotels with an average price of $75 per night

How to get to De Soto

Fly in to St. Louis, MO (STL-Lambert-St. Louis Intl.), 44.8 mi (72 km) from downtown De Soto.

What to see around De Soto

Some recommended places to see include:
  • • Sunridge Park
  • • Persimmon Ridge Winery
  • • St. James Catholic Church
  • • Washington County Courthouse

When to visit De Soto

Wondering when's the best time to visit? Here are seasonal norms to help you plan your trip:

Seasonal temperature averages
  • • January-March: 62°F day, 22°F night
  • • April-June: 87°F day, 39°F night
  • • July-September: 88°F day, 49°F night
  • • October-December: 73°F day, 22°F night
Seasonal rainfall averages
  • • January-March: 8.6 inches
  • • April-June: 13.2 inches
  • • July-September: 11.3 inches
  • • October-December: 11.5 inches