Hotels in Old Appleton

Free cancellation options if plans change

Unlock travel rewards with One Key

Save more with Member Prices

Check prices for these dates

Tonight

Tomorrow

This weekend

Next weekend

Top 5 hotels in Old Appleton at a glance

Drury Plaza Hotel Cape Girardeau Conference Center — 3-star hotel in Cape Girardeau. Guest rating: 9.6/10 — Exceptional.
The Riverview — 4-star hotel in Cape Girardeau. Guest rating: 9.4/10 — Exceptional.
Drury Inn & Suites Jackson MO — 3-star hotel in Jackson. Guest rating: 9.6/10 — Exceptional.
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau — 3-star hotel in Jackson. Guest rating: 9.0/10 — Wonderful.
Drury Inn & Suites Cape Girardeau — 3-star hotel in Cape Girardeau. Guest rating: 9.4/10 — Exceptional.

Where to stay in Old Appleton?

Properties are selected based on real traveler reviews and popularity among guests who’ve booked a night in Old Appleton on Hotels.com. These Old Appleton hotels consistently deliver on comfort, location and traveler experience. Last updated on August 28, 2026.

Drury Plaza Hotel Cape Girardeau Conference Center

Cape Girardeau

$100 nightly

$113 total

Sep 2 - Sep 3

Total with taxes and fees

The Riverview

Cape Girardeau

$107 nightly

$120 total

Sep 1 - Sep 2

Total with taxes and fees

Drury Inn & Suites Jackson MO

Jackson

$85 nightly

$90 total

Sep 22 - Sep 23

Total with taxes and fees

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

Jackson

$93 nightly

$100 total

Aug 31 - Sep 1

Total with taxes and fees

Drury Inn & Suites Cape Girardeau

Cape Girardeau

$90 nightly

$102 total

Sep 6 - Sep 7

Total with taxes and fees

Holiday Inn Express & Suites Murphysboro - Carbondale by IHG

Murphysboro

$111 nightly

$123 total

Sep 28 - Sep 29

Total with taxes and fees

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Cape Girardeau

$99 nightly

$112 total

Sep 27 - Sep 28

Total with taxes and fees

Pear Tree Inn Cape Girardeau West

Cape Girardeau

$72 nightly

$81 total

Sep 6 - Sep 7

Total with taxes and fees

Candlewood Suites Cape Girardeau by IHG

Cape Girardeau

$85 nightly

$101 total

Sep 27 - Sep 28

Total with taxes and fees

Fairfield Inn & Suites by Marriott Cape Girardeau

Cape Girardeau

$101 nightly

$114 total

Sep 3 - Sep 4

Total with taxes and fees

Courtyard by Marriott Cape Girardeau Downtown

Cape Girardeau

$125 nightly

$142 total

Sep 6 - Sep 7

Total with taxes and fees

Room, 2 Queen Beds, Accessible, Bathtub (Mobility & Hearing)

Tru By Hilton Cape Girardeau

Cape Girardeau

$89 nightly

$102 total

Sep 3 - Sep 4

Total with taxes and fees

Room, 1 King Bed, Accessible, Non Smoking

Quality Inn Cape Girardeau North

Cape Girardeau

$62 nightly

$70 total

Sep 6 - Sep 7

Total with taxes and fees

Room, 2 Queen Beds, Non Smoking, Refrigerator & Microwave

Hampton Inn Cape Girardeau I 55 East

Cape Girardeau

$106 nightly

$119 total

Sep 3 - Sep 4

Total with taxes and fees

Holiday Inn Express & Suites Perryville by IHG

Perryville

$97 nightly

$111 total

Sep 3 - Sep 4

Total with taxes and fees

Deluxe Studio Suite, 1 King Bed, Non Smoking | Jetted tub

Deluxe Studio Suite, 1 King Bed, Non Smoking | Bathroom

Baymont by Wyndham Chester IL

Chester

$81 nightly

$90 total

Aug 30 - Aug 31

Total with taxes and fees

Suite, 1 King Bed, Non Smoking (1 Bedroom)

Studio Suite, 1 King Bed, Accessible, Non Smoking (Mobility Accessible)

Super 8 by Wyndham Perryville

Perryville

$65 nightly

$74 total

Sep 15 - Sep 16

Total with taxes and fees

The Atrium - A Boutique Hotel

Perryville

$146 nightly

$167 total

Aug 30 - Aug 31

Total with taxes and fees

EC Reed's Mercantile and Hotel

Marble Hill

$92 nightly

$100 total

Sep 8 - Sep 9

Total with taxes and fees

Urban Lofts

Perryville

$295 nightly

$338 total

Aug 29 - Aug 30

Total with taxes and fees

View all properties

Go beyond your typical stay in Old Appleton

Pet friendly

Pool

Check out reviews of Old Appleton hotels guests love

Holiday Inn Express & Suites Perryville by IHG

10/10 Excellent

"We had a pleasnt stay for a reasonable price. Our room was clean and quiet. The beds and pillows were comfortable. Breakfast was good with hot and cold choices. The staff was friendly and helpful."

Tru By Hilton Cape Girardeau

8/10 Good

"Staff was friendly and welcoming."

Perryville RV Resort

10/10 Excellent

"Great time"

Frequently asked questions

How much does a hotel room cost in Old Appleton?

You can find top hotels in Old Appleton from $70 with options to suit your budget and needs. If you're after an affordable hotel in Old Appleton that meets all of your requirements, set your filters and then sort the results by "Price: low to high".

How can I find deals and earn rewards at Old Appleton hotels?

Discover great deals on Old Appleton hotel stays with Hotels.com. You can also look at hotel prices mid-week or during the low season to find off-peak deals. If it's a spontaneous trip, check out our last-minute deals on Old Appleton hotels.

Can I book Old Appleton hotels with free cancellation?

To book a refundable Old Appleton hotel on Hotels.com, just filter hotels by "Property cancellation options" and select "Fully refundable property". Most hotels offer free cancellation, so you can receive a refund if you need to cancel. Some hotels do require cancelling more than 24 hours before check-in, so double-check your booking beforehand.

Can I book a refundable hotel in Old Appleton?

If you're looking for the flexibility to change your travel plans to Old Appleton, most hotels offer refundable* bookable rates. You can see these accommodations by searching our site and using the "fully refundable" filter to narrow the results down.

What will the weather in Old Appleton be like during my visit?

The warmest months in Old Appleton are usually July and August with an average temp of 76°F. January and February are the chilliest months when the average temp is 40°F. The rainiest months are April and March.

Why should I book my Old Appleton hotel through Hotels.com?

There are plenty of reasons to book your Old Appleton travel with us: our free cancellations on selected hotels gives you the flexibility you're looking for, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.

Keep exploring

Lodging