Hotels in Santa Ana

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Where to stay in Santa Ana?

Properties are selected based on real traveler reviews and popularity among guests who’ve booked a night in Santa Ana on Hotels.com. These Santa Ana hotels consistently deliver on quality, location and traveler experience. Last updated on .

1. Hotel Caracas - Casco Viejo

Hotel Caracas - Casco Viejo
3.0 star property
Santa Ana
8.0 out of 10, Very good, (19 reviews)
"We stayed one night there. Very comfortable location. The room was clean, nice shower, helpful and friendly staff, and they have good coffee in the lobby :)"
United Kingdom
Lital
$36 nightly
The price is $40
Oct 27 - Oct 28
Total with taxes and fees
Hotel Caracas - Casco Viejo

2. Casco View Life Residences

Casco View Life Residences
4.0 star property
Santa Ana
9.0 out of 10, Wonderful, (107 reviews)
"Wow! Just a couple of blocks from the Casco Viejo this place is a gem. Large modern apartments at a very affordable price. Nice pool to enjoy and beat the heat. Bikes available. The concierge service is outstanding."
Canada
Glenn
$106 nightly
The price is $117
Oct 6 - Oct 7
Total with taxes and fees
Casco View Life Residences

3. La Manzana Barrio Vivo by Wynwood

La Manzana Barrio Vivo by Wynwood
3.0 star property
Santa Ana
7.6 out of 10, Good, (19 reviews)
"Very clean and safe property"
United States
Javier Alberto Lindauer
$95 nightly
The price is $104
Oct 7 - Oct 8
Total with taxes and fees
La Manzana Barrio Vivo by Wynwood

4. Hotel Riazor

Hotel Riazor
3.0 star property
Santa Ana
3.8 out of 10, (11 reviews)
"Rough neighborhood "
Canada
Del
$24 nightly
The price is $27
Oct 16 - Oct 17
Total with taxes and fees
Hotel Riazor

5. Hostal La Cigarra

Hostal La Cigarra
2.0 star property
Santa Ana
7.6 out of 10, Good, (75 reviews)
"Excellent staff, close to metro and embassies. A good location, good room for a great price. I would stay again. "
United Kingdom
Mark
$24 nightly
The price is $27
Oct 15 - Oct 16
Total with taxes and fees
Hostal La Cigarra

6. Hotel República

Hotel República
2.0 star property
Santa Ana
6.8 out of 10, Good, (197 reviews)
"Good location. Walking distance to shops and public transport."
Canada
Danilo
$80 nightly
The price is $88
Nov 4 - Nov 5
Total with taxes and fees
Hotel República

7. ART CASCO The Hotel

ART CASCO The Hotel
2.0 star property
Santa Ana
6.0 out of 10, Good, (13 reviews)
"Walkable location and free secure parking! The price is really affordable, but the condition of the hotel is not the best"
United States
Eldris
$32 nightly
The price is $35
Oct 19 - Oct 20
Total with taxes and fees
ART CASCO The Hotel

8. Room-sofa Bed Stay Rooftop Pool & Gym, A

Room-sofa Bed Stay Rooftop Pool & Gym, A
2.0 star property
Santa Ana
2.0 out of 10, (1 review)
"You pay for a space in the apartment, it’s not the whole apartment be careful. The owner or whoever manages doesn’t give care about you as costumers they just want the money"
United States
Cristian Camilo Betancur
$105 nightly
The price is $115
Oct 7 - Oct 8
Total with taxes and fees
Room-sofa Bed Stay Rooftop Pool & Gym, A

9. Tantalo Hotel

Tantalo Hotel
3.5 star property
San Felipe, 0.4 mi from Santa Ana
8.8 out of 10, Excellent, (338 reviews)
"Super good location, very nice restaurant."
United States
SUSAN
$77 nightly
The price is $85
Oct 27 - Oct 28
Total with taxes and fees
Tantalo Hotel

10. The Executive Hotel

The Executive Hotel
3.5 star property
Campo Alegre, 2 mi from Santa Ana
9.2 out of 10, Wonderful, (1,274 reviews)
"Really nice hotel overall specially good value for money, good location (situated right in the city and very close to Casco Viejo), spacious/bright/modern/clean room, good facilities (nice pool, big gym, decent restaurant/entrance area), good customer service from the staff, alright breakfast included too. Really recommend if you’re staying in Panama City for a few nights."
United Kingdom
Mariana
$89 nightly
The price is $98
Oct 27 - Oct 28
Total with taxes and fees
The Executive Hotel

11. Principe Hotel and Suites

Principe Hotel and Suites
3.0 star property
El Cangrejo, 2.4 mi from Santa Ana
9.0 out of 10, Wonderful, (2,086 reviews)
"Great location next to restaurants, walkable in Panama City"
United States
Paul
$59 nightly
The price is $65
Oct 6 - Oct 7
Total with taxes and fees
Principe Hotel and Suites

12. Hotel Riu Plaza Panama

Hotel Riu Plaza Panama
5.0 star property
Campo Alegre, 2.2 mi from Santa Ana
9.0 out of 10, Wonderful, (6,018 reviews)
"Riu Plaza was an excellent choice for our 5 day stay in Panamá! It was like a resort in the middle of a big, busy city! The staff was amazing. The breakfast buffet was a delight with different offerings every day. The location was great and every driver knew where to pick us up when we said that we were staying at the Riu Plaza."
United States
Karen
$132 nightly
The price is $145
Oct 21 - Oct 22
Total with taxes and fees
Hotel Riu Plaza Panama

13. Hotel Mio Panama

Hotel Mio Panama
3.0 star property
Campo Alegre, 2.2 mi from Santa Ana
8.6 out of 10, Excellent, (249 reviews)
"All the food was good and the staff was AMAZING!!!"
United States
Brittany
$50 nightly
The price is $56
Oct 7 - Oct 8
Total with taxes and fees
Hotel Mio Panama

14. Riande Urban Hotel

Riande Urban Hotel
3.5 star property
El Cangrejo, 2.4 mi from Santa Ana
8.8 out of 10, Excellent, (1,035 reviews)
"My favorite hotel and location in Panama City. Rooms are clean staff helpful."
United States
Yvette
$74 nightly
The price is $82
Oct 6 - Oct 7
Total with taxes and fees
Riande Urban Hotel

15. Plaza Paitilla Inn Hotel

Plaza Paitilla Inn Hotel
3.5 star property
Punta Paitilla, 2.1 mi from Santa Ana
9.4 out of 10, Exceptional, (2,235 reviews)
"Great location and beautiful sunrises if you have a Bayview room. Easy to walk and Uber. Breakfast is great too."
United States
safiyyah
$108 nightly
The price is $108
Oct 14 - Oct 15
Total with taxes and fees
Plaza Paitilla Inn Hotel

16. Hotel Magnolia Boutique

Hotel Magnolia Boutique
2.0 star property
San Felipe, 0.4 mi from Santa Ana
8.8 out of 10, Excellent, (523 reviews)
"Hotel Magnolia was a great experience. The room was superb and clean and very well lit. Location is prime. The staff was helpful and engaging and I enjoyed my stay there. Would come back again."
United States
Layal
$90 nightly
The price is $99
Oct 12 - Oct 13
Total with taxes and fees
Hotel Magnolia Boutique

17. Hotel Bardot Boutique

Hotel Bardot Boutique
3.0 star property
San Felipe, 0.7 mi from Santa Ana
9.0 out of 10, Wonderful, (56 reviews)
"Extraordinary location, nice decor, very kind and helpful staff, delicious breakfast and good dinner / bar option. "
Brazil
Gabriela
$82 nightly
The price is $91
Oct 11 - Oct 12
Total with taxes and fees
Hotel Bardot Boutique

18. Radisson Hotel Panama Canal

Radisson Hotel Panama Canal
4.5 star property
Amador, 1.4 mi from Santa Ana
8.6 out of 10, Excellent, (1,004 reviews)
"Great location directly at the canal with views to the ships and large pool. Walking distance to museum and easy drives to canal visitors centre and peninsula for island hopping. And: very friendly personell! Good breakfast, of course rooms are a bit outdated though…"
Germany
Tilmann
$78 nightly
The price is $86
Oct 6 - Oct 7
Total with taxes and fees
Radisson Hotel Panama Canal

19. Waymore Hotel Spa & Casino

Waymore Hotel Spa & Casino
4.0 star property
El Cangrejo, 2.2 mi from Santa Ana
9.0 out of 10, Wonderful, (1,179 reviews)
"Hotel Waymore is a great place to stay. It is footsteps away from restaurants and shops."
United States
Gregory
$121 nightly
The price is $135
Nov 1 - Nov 2
Total with taxes and fees
Waymore Hotel Spa & Casino

20. American Trade Hotel

American Trade Hotel
4.5 star property
San Felipe, 0.4 mi from Santa Ana
9.4 out of 10, Exceptional, (818 reviews)
"Great spot, charming, beautiful decor, wonderful location"
United States
Puneh
$169 nightly
The price is $187
Oct 12 - Oct 13
Total with taxes and fees
American Trade Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Compare popular hotels in Santa Ana

Property
Star rating
Guest rating
Breakfast included
Pool
Spa
Pet friendly
WiFi included
A modern indoor pool area with clear blue water, lounge chairs, and a wall of plants.
Casco View Life Residences
4.0 star property
9.0
Wonderful
107 reviews
View
A hotel corridor with a wooden railing, doors, and wall-mounted plants.
Hotel Caracas - Casco Viejo
3.0 star property
8.0
Very good
19 reviews
View
A bar area with a curved counter, multiple seating options, and a variety of bottles and glasses on display.
Hotel Riazor
3.0 star property
3.8
11 reviews
View
A restaurant with a long counter, chairs, and tables. There are plants and lights decorating the space.
Hostal La Cigarra
2.0 star property
7.6
Good
75 reviews
View
A modern hotel room with a large bed, a sofa, a TV, and a view of the city.
La Manzana Barrio Vivo by Wynwood
3.0 star property
7.6
Good
19 reviews
View

When is the best time to visit Santa Ana?

Our prices for hotels in Santa Ana are cheapest in January
Price trends for hotels in Santa Ana
Pricing is based on two traveler single night rates
View properties in October
Currently viewing crowd sizes and weather for October.
Typical weather for Panama City
October
High 84°F / low 75°F. Rainy most days.
View properties in October
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October, no crowd data, average high temperature 84 degrees Fahrenheit, average low temperature 75 degrees Fahrenheit. Rainy most days.
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November, no crowd data, average high temperature 83 degrees Fahrenheit, average low temperature 75 degrees Fahrenheit. Rainy most days.
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85°
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December, no crowd data, average high temperature 85 degrees Fahrenheit, average low temperature 75 degrees Fahrenheit. Cloudy most days.
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85°
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January, no crowd data, average high temperature 85 degrees Fahrenheit, average low temperature 74 degrees Fahrenheit. Sunny most days.
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86°
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February, no crowd data, average high temperature 86 degrees Fahrenheit, average low temperature 74 degrees Fahrenheit. Sunny most days.
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87°
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March, no crowd data, average high temperature 87 degrees Fahrenheit, average low temperature 74 degrees Fahrenheit. Sunny most days.
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87°
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April, no crowd data, average high temperature 87 degrees Fahrenheit, average low temperature 76 degrees Fahrenheit. Sunny most days.
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86°
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May, no crowd data, average high temperature 86 degrees Fahrenheit, average low temperature 76 degrees Fahrenheit. Rainy most days.
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85°
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June, no crowd data, average high temperature 85 degrees Fahrenheit, average low temperature 76 degrees Fahrenheit. Rainy most days.
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85°
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July, no crowd data, average high temperature 85 degrees Fahrenheit, average low temperature 76 degrees Fahrenheit. Rainy most days.
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84°
weather_sleet
August, no crowd data, average high temperature 84 degrees Fahrenheit, average low temperature 76 degrees Fahrenheit. Rainy most days.
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85°
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September, no crowd data, average high temperature 85 degrees Fahrenheit, average low temperature 76 degrees Fahrenheit. Rainy most days.
76°
Monthly weather averages (˚F)

Top landmarks in Santa Ana

Check out reviews of Santa Ana hotels guests love

Frequently asked questions

Is Santa Ana expensive to stay in?
You can find great hotels from $21 in Santa Ana to suit a range of budgets. If you're looking for an affordable stay in Santa Ana, Hostal La Cigarra is a great low-cost option. To find the best low-cost hotel on Hotels.com that meets your needs, apply your search filters and then sort hotels by "Price: low to high".
How can I find discounted rates and deals for Santa Ana hotels?
Discover great deals on hotels in Santa Ana with Hotels.com. Sign up for free to unlock member only prices and start earning rewards. It's also a good idea to look at hotel prices mid-week or during the low season as you're likely to find off-peak deals. If you're up for a spontaneous trip, don't forget to check out our last-minute deals on Santa Ana hotels.
Can I receive a refund if I cancel my Santa Ana hotel booking?
The majority of hotels offer free cancellation, so you can receive a refund if you need to cancel your booking. Some Santa Ana hotels require you to cancel more than 24 hours before check-in, so look at your booking beforehand. For extra peace of mind before you book, filter hotels by "Property cancellation options" and select "Fully refundable property".
Is it worth staying in Santa Ana?
You're spoilt for choice with 130 hotels in the area so it's easy to find your perfect somewhere. Basing yourself in Santa Ana makes it easy to explore Panama City, including the neighborhoods of Casco Viejo and Bella Vista.
Find out more about Santa Ana

Santa Ana: Where Nature's Beauty Meets Cultural Treasures

Nestled in the heart of Panama City, Santa Ana is a vibrant neighborhood that seamlessly blends history and culture. Stroll through its charming streets, where colonial architecture meets lively street art, and discover the iconic Iglesia de Santa Ana. The lush Santa Ana Park offers a serene escape, perfect for relaxation or a picnic. Explore nearby museums that showcase Panama’s rich heritage and immerse yourself in the local atmosphere. With its unique blend of historical significance and contemporary flair, Santa Ana invites travelers to experience the soul of Panama City, making it a must-visit gem off the beaten path.

Discover great hotels near Santa Ana

In Santa Ana, Panama City, you’ll find a range of hotel options, from cozy boutique stays to larger properties, catering to various budgets. Santa Ana Arriba offers a quieter atmosphere, ideal for relaxation, while the area is conveniently close to local attractions and dining options. Here are some of the best hotels near Santa Ana that our travelers love:

  1. Socialtel Casco Viejo Panama CityOpens in a new window: This charming 3.0-star hotel offers a vibrant city-themed experience right in the heart of Santa Ana. Perfect for leisure travelers, it presents easy access to local attractions and the dynamic atmosphere of the city center. With a focus on socializing and connecting with fellow travelers, this hostel-style lodging provides a unique opportunity to immerse oneself in the culture of Panama. Its welcoming ambiance and central location make it an ideal choice for those seeking an affordable yet engaging vacation experience.
  2. La Concordia Boutique HotelOpens in a new window: La Concordia Boutique Hotel is a sophisticated 4.0-star hotel that caters to discerning leisure travelers seeking a blend of romance and family-friendly amenities. With a stellar guest rating of 9.6, this hotel impresses with its spacious, comfortable rooms and a prime location. Guests can indulge in spa services, including in-room massages, and enjoy delightful meals at the on-site restaurant. The beautiful rooftop bar and thoughtfully designed romance packages elevate the experience, making it a top choice for those wanting a luxurious escape in Santa Ana.
  3. Hotel Casa PanamáOpens in a new window: Known for its stylish design and pet-friendly policy, Hotel Casa Panamá is a striking 4.0-star hotel that draws leisure travelers looking for a memorable city break. Located in the bustling city center, it is easy to explore local attractions and vibrant nightlife. The hotel boasts an excellent restaurant and stunning views, ensuring an enjoyable dining experience. With its unique offerings and attention to detail, this hotel provides a delightful stay for those wanting to immerse themselves in the charm of Santa Ana.

Where to stay near Santa Ana

Some of the best places to stay near the Metropolitan Cathedral of Panama, Interoceanic Canal Museum, and Flag of Cerro Ancón are in Santa Ana, Panama City, Panamá Province, Panama. The Metropolitan Cathedral offers stunning architecture and vibrant local culture, while the Interoceanic Canal Museum provides fascinating insights into Panama's history. The Flag of Cerro Ancón boasts breathtaking views. For first-time visitors, staying near the Metropolitan Cathedral is ideal for a rich cultural experience.

  1. Near Metropolitan Cathedral of PanamaOpens in a new window: Staying near this stunning cathedral places you in the heart of Panama City's rich history and culture. You can easily explore the surrounding area, which is filled with charming shops and friendly locals. Don't miss the chance to wander through the nearby markets and enjoy the vibrant atmosphere, while also taking in the beautiful architectural details of the cathedral itself.
  2. Near Interoceanic Canal MuseumOpens in a new window: This museum is a treasure trove of information about the history of the Panama Canal, making it a fascinating spot for history buffs. Staying nearby allows you to dive deep into Panama's maritime heritage while enjoying easy access to shopping and friendly local interactions. The museum's exhibits offer a unique perspective on the canal's impact on global trade and transportation.
  3. Near Flag of Cerro AncónOpens in a new window: Visiting the Flag of Cerro Ancón gives you a chance to appreciate one of Panama City's most iconic landmarks. The area around it is perfect for leisurely walks and offers stunning views of the city. It's a peaceful spot to enjoy nature while still being close to the vibrant urban life, providing a nice balance of tranquility and local culture.

Things to do in Santa Ana

Santa Ana offers travelers a delightful blend of lush parks, vibrant markets, and a rich historical atmosphere, ideal for leisurely strolls and shopping excursions. Explore scenic walking paths, relax in natural green spaces, and enjoy outdoor activities like hiking or boating, all while soaking in the area's charming ambiance.

  • Avenida BalboaOpens in a new window – Stroll along Avenida Balboa, a vibrant street that offers stunning views of the Pacific Ocean. This scenic promenade is perfect for a leisurely walk or bike ride, with plenty of green spaces and places to relax along the way.
  • Amador CausewayOpens in a new window – Take a trip to the Amador Causeway, a beautiful monument that connects several small islands to the mainland. Enjoy the fresh sea breeze as you walk or bike the path, with impressive views of the Panama City skyline and the Panama Canal.
  • Via EspanaOpens in a new window – Explore Via Espana, a bustling street known for its local shops and eateries. It's a great spot to experience everyday Panamanian life and grab a bite to eat or a refreshing drink from a nearby café.
  • Panama Canal MuralsOpens in a new window – Discover the Panama Canal Murals, where vibrant street art tells the story of the canal's history and its significance to the nation. These colorful artworks offer a unique glimpse into Panama's culture and heritage.
  • Panama ViejoOpens in a new window – Step back in time at Panama Viejo, a historic site that showcases the ruins of the original Panama City. Wander through the remnants of this once-thriving city and learn about its fascinating past through informative displays.

5 tips for savvy savings when booking a hotel in Santa Ana

  1. Book for the cheapest times: The most budget-friendly time to visit Santa Ana is from September to November, when hotel prices are generally lower. To fully experience the city's landmarks, cultural sites, and historical attractions, it's recommended to stay for at least 3 to 4 days. During your visit, you can enjoy the local seafood, explore museums, stroll through natural parks, and engage in shopping, all while interacting with the friendly locals. This timeframe offers great value for money, allowing you to make the most of your trip without breaking the bank.
  2. Instant discounts. Rewards for later: Save up to 20% instantly on hundreds of thousands of properties with Member Discounts. Then earn rewards on eligible stays to use on future trips. Book once, win twice, get instant discounts and rewards. Join for freeOpens in a new window.
  3. Score last-minute deals on Hotels.com: Last-minute travel doesn't mean last-minute stress. Hotels.com's Last-Minute DealsOpens in a new window offer discounted rates close to your travel date, so the later you leave it, the more you could save. Turn on push notifications and you'll be the first to know when dealsOpens in a new window drop for Santa Ana.
  4. Book with confidence, not guesswork: Prices in Santa Ana shift with the season, local events, and how far out you book — but you don't have to guess. Hotels.com shows you the full price upfront with no surprises at checkout, and our price tracker tells you whether your dates are above or below average. So if you're flexible, you can shift your trip by a day or two to avoid peak season prices, compare pricesOpens in a new window and know you're getting a good deal before you commit.
  5. Think beyond the city center: Central hotels may come with a central price tag. A well-connected neighborhood a little further out may cut your hotel bill and can often give you a more local experience. Use Hotels.com's map view to find the sweet spot between location and value, and filter by price to see what's available across Santa Ana.

Best time to go to Santa Ana

Santa Ana has a varied climate due to its size, so the best time to visit depends on the region and your preferences for weather and crowds. January, February, and December are the peak travel months in Santa Ana, attracting a higher number of tourists. During this peak period, the weather is mostly sunny to mostly cloudy, accompanied by no to light rainfall. On the other hand, May, June, and September tend to be quieter times to visit, marked by frequent rainfall and mostly cloudy conditions.

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