Hotels in Panacea

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Where to stay in Panacea?

The Panacea Motel

The Panacea Motel
2.0 star property
Panacea
9.0 out of 10, Wonderful, (171 reviews)
Escape to this waterfront motel where adventure awaits with hiking trails and kayaking right on the property. Explore nearby Panacea Springs and Woolley Park before returning to enjoy free WiFi and parking. Just 47 minutes from Tallahassee Airport.
$114 nightly
The price is $127
May 31 - Jun 1
Total with taxes and fees
The Panacea Motel

BOB Hotels Tallahassee - Boutique on Budget

BOB Hotels Tallahassee - Boutique on Budget
3.0 star property
Tallahassee
9.0 out of 10, Wonderful, (2,222 reviews)
$77 nightly
The price is $86
May 27 - May 28
Total with taxes and fees
BOB Hotels Tallahassee - Boutique on Budget

Wildwood Inn

Wildwood Inn
3.0 star property
Crawfordville
8.6 out of 10, Excellent, (1,000 reviews)
$128 nightly
The price is $142
Jun 4 - Jun 5
Total with taxes and fees
Wildwood Inn

Hyatt House Tallahassee Capitol – University

Hyatt House Tallahassee Capitol – University
3.0 star property
Railroad Square Art District
9.0 out of 10, Wonderful, (1,654 reviews)
Art Deco style meets modern comfort at this centrally located hotel near Railroad Square Art Park. Cool off in the outdoor pool, grab dinner at H Bar, or keep up with workouts in the 24-hour fitness center.
$110 nightly
The price is $124
Jun 5 - Jun 6
Total with taxes and fees
Hyatt House Tallahassee Capitol – University

Best Western Wakulla Inn & Suites

Best Western Wakulla Inn & Suites
2.5 star property
Crawfordville
8.8 out of 10, Excellent, (982 reviews)
$124 nightly
The price is $138
Jun 4 - Jun 5
Total with taxes and fees
Best Western Wakulla Inn & Suites

Four Points by Sheraton Tallahassee Downtown

Four Points by Sheraton Tallahassee Downtown
3.0 star property
Governor's Walk
8.6 out of 10, Excellent, (1,129 reviews)
Experience convenient comfort near Florida State and Florida A&M universities, just a short drive away. Take a refreshing dip in the outdoor pool, dine at Juicy Blue restaurant, or unwind at one of 2 bars. Guests love the comfortable beds, helpful staff, and free parking.
$102 nightly
The price is $115
Jun 7 - Jun 8
Total with taxes and fees
Four Points by Sheraton Tallahassee Downtown

Wyndham Garden Tallahassee Capitol

Wyndham Garden Tallahassee Capitol
3.0 star property
Tallahassee
5.8 out of 10, (1,231 reviews)
Discover a central Tallahassee retreat near Florida State and A&M universities with free breakfast, WiFi, and parking. Unwind in the outdoor pool, energize in the 24-hour fitness center, and enjoy the comfy beds that guests consistently praise.
$42 nightly
The price is $47
May 31 - Jun 1
Total with taxes and fees
Wyndham Garden Tallahassee Capitol

DoubleTree by Hilton Hotel Tallahassee

DoubleTree by Hilton Hotel Tallahassee
4.0 star property
Capitol Hill
7.4 out of 10, Good, (1,002 reviews)
Unwind in the outdoor pool after exploring nearby universities and downtown attractions. This hotel offers a welcoming bar, café, and 24-hour fitness center just minutes from Tallahassee Downtown Market and Knott House Museum.
$102 nightly
The price is $115
May 25 - May 26
Total with taxes and fees
DoubleTree by Hilton Hotel Tallahassee

St James Bay Golf & Pickleball Resort

St James Bay Golf & Pickleball Resort
3.5 star property
Carrabelle
9.0 out of 10, Wonderful, (394 reviews)
Escape to this Carrabelle resort offering an 18-hole golf course, outdoor pool, and rejuvenating massages. After a round, relax at the bar or dine at the restaurant. Rooms include washers, dryers, and microwaves for added comfort during your stay.
$181 nightly
The price is $200
May 22 - May 23
Total with taxes and fees
St James Bay Golf & Pickleball Resort

The Lodge at Wakulla Springs

The Lodge at Wakulla Springs
3.0 star property
Crawfordville
9.4 out of 10, Exceptional, (1,003 reviews)
Set in Wakulla Springs State Park, this historic hotel offers American cuisine at Edward Ball Dining Room and outdoor adventures with a terrace for relaxing. Enjoy free WiFi and parking with easy access to Wakulla State Forest and Tallahassee.
$106 nightly
The price is $118
Jun 2 - Jun 3
Total with taxes and fees
The Lodge at Wakulla Springs

Hotel Indigo Tallahassee - Collegetown by IHG

Hotel Indigo Tallahassee - Collegetown by IHG
3.5 star property
College Town
9.2 out of 10, Wonderful, (1,000 reviews)
Trendy hotel near Florida State and FAMU universities with a lively bar and R&R Eatery serving breakfast and dinner. Just minutes from Railroad Square Art Park, this convenient location offers a 24-hour fitness center and is praised for its helpful staff.
$134 nightly
The price is $150
May 25 - May 26
Total with taxes and fees
Hotel Indigo Tallahassee - Collegetown by IHG

Aloft by Marriott Tallahassee Downtown

Aloft by Marriott Tallahassee Downtown
3.0 star property
Capitol Hill
8.8 out of 10, Excellent, (1,000 reviews)
Experience urban comfort near Florida's universities with an outdoor pool and WXYZ restaurant serving breakfast and dinner. The fitness center and bar/lounge enhance your stay, while helpful staff ensure a pleasant visit close to downtown attractions.
$110 nightly
The price is $123
May 29 - May 30
Total with taxes and fees
Aloft by Marriott Tallahassee Downtown

Courtyard by Marriott Tallahassee Downtown/Capitol

Courtyard by Marriott Tallahassee Downtown/Capitol
3.0 star property
Tallahassee
8.4 out of 10, Very Good, (1,006 reviews)
Close to FSU and FAMU, this Courtyard by Marriott offers a quiet retreat with an outdoor pool and The Bistro serving American fare. Myers Park and Parkway Shopping Center are nearby, plus you'll enjoy free WiFi and parking.
$87 nightly
The price is $98
May 29 - May 30
Total with taxes and fees
Courtyard by Marriott Tallahassee Downtown/Capitol

SpringHill Suites Tallahassee Central

SpringHill Suites Tallahassee Central
3.0 star property
Tallahassee
8.8 out of 10, Excellent, (1,000 reviews)
Just minutes from Florida State and Florida A&M universities, this hotel offers an outdoor pool and 24-hour fitness center. Clean rooms and helpful staff earn top reviews, while free breakfast and WiFi add value. Hilaman Golf Course and Governor's Square Mall are nearby.
$102 nightly
The price is $115
May 25 - May 26
Total with taxes and fees
SpringHill Suites Tallahassee Central

Hotel Duval, Autograph Collection

Hotel Duval, Autograph Collection
4.0 star property
Governor's Walk
8.0 out of 10, Very Good, (1,011 reviews)
Enjoy panoramic views from the rooftop terrace at this Tallahassee hotel near Florida State and A&M universities. With 2 bars, a café, and 24-hour fitness center, you're perfectly positioned to explore the Florida Governor's Mansion and LeMoyne Art Gallery.
$122 nightly
The price is $138
May 25 - May 26
Total with taxes and fees
Hotel Duval, Autograph Collection

Fairfield Inn & Suites by Marriott Tallahassee Central

Fairfield Inn & Suites by Marriott Tallahassee Central
3.0 star property
Tallahassee
8.6 out of 10, Excellent, (1,000 reviews)
$97 nightly
The price is $109
May 31 - Jun 1
Total with taxes and fees
Fairfield Inn & Suites by Marriott Tallahassee Central

Hampton Inn & Suites Tallahassee Capitol - University

Hampton Inn & Suites Tallahassee Capitol - University
2.5 star property
Railroad Square Art District
9.0 out of 10, Wonderful, (1,000 reviews)
Kick back at this Tallahassee hotel near Florida State University and Florida A&M. The outdoor pool offers refreshing dips after exploring Railroad Square Art Park. With free breakfast, WiFi, and Tallahassee Station just 2 minutes away, adventure awaits.
$115 nightly
The price is $129
May 31 - Jun 1
Total with taxes and fees
Hampton Inn & Suites Tallahassee Capitol - University

Home2 Suites by Hilton Tallahassee State Capitol

Home2 Suites by Hilton Tallahassee State Capitol
3.0 star property
Tallahassee
8.4 out of 10, Very Good, (1,001 reviews)
Travelers praise the helpful staff at this hotel featuring a 24-hour fitness center and outdoor pool. Just a short drive from Parkway Shopping Center, Governor's Square Mall, and Tallahassee Station, with free breakfast and WiFi.
$99 nightly
The price is $112
May 29 - May 30
Total with taxes and fees
Home2 Suites by Hilton Tallahassee State Capitol

Holiday Inn Tallahassee E Capitol - Univ by IHG

Holiday Inn Tallahassee E Capitol - Univ by IHG
3.0 star property
Tallahassee
9.2 out of 10, Wonderful, (1,001 reviews)
Discover a convenient Tallahassee hotel near FSU and Florida A&M University. The indoor pool and 24-hour fitness center offer year-round relaxation while Capitol Cafe & Bar serves American cuisine. Rooms include refrigerators and microwaves for added comfort.
$101 nightly
The price is $114
May 24 - May 25
Total with taxes and fees
Holiday Inn Tallahassee E Capitol - Univ by IHG

Comfort Suites Tallahassee Capitol - University Area

Comfort Suites Tallahassee Capitol - University Area
2.5 star property
Tallahassee
8.2 out of 10, Very Good, (1,000 reviews)
This peaceful hotel sits just minutes from Florida State and Florida A&M universities. Enjoy the outdoor pool after exploring nearby Myers Park. Complimentary perks include WiFi, parking, and breakfast that guests consistently praise alongside the helpful staff.
$95 nightly
The price is $107
May 27 - May 28
Total with taxes and fees
Comfort Suites Tallahassee Capitol - University Area
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

When is the best time to visit Panacea?

Our prices for hotels in Panacea are cheapest in February
Price trends for hotels in Panacea
Pricing is based on two traveler single night rates
View properties in May
Currently viewing crowd sizes and weather for May.
Typical weather for Panacea
May
High 84°F / low 67°F. Sunny most days.
View properties in May
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May, no crowd data, average high temperature 84 degrees Fahrenheit, average low temperature 67 degrees Fahrenheit. Sunny most days.
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July, no crowd data, average high temperature 89 degrees Fahrenheit, average low temperature 76 degrees Fahrenheit. Partly sunny.
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August, no crowd data, average high temperature 89 degrees Fahrenheit, average low temperature 76 degrees Fahrenheit. Partly sunny.
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September, no crowd data, average high temperature 86 degrees Fahrenheit, average low temperature 73 degrees Fahrenheit. Sunny most days.
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October, no crowd data, average high temperature 80 degrees Fahrenheit, average low temperature 64 degrees Fahrenheit. Sunny most days.
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November, no crowd data, average high temperature 71 degrees Fahrenheit, average low temperature 55 degrees Fahrenheit. Sunny most days.
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March, no crowd data, average high temperature 72 degrees Fahrenheit, average low temperature 55 degrees Fahrenheit. Sunny most days.
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April, no crowd data, average high temperature 77 degrees Fahrenheit, average low temperature 61 degrees Fahrenheit. Sunny most days.
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Monthly weather averages (˚F)

Top landmarks in Panacea

Learn more about Panacea

Notable for its natural beauty, Panacea features attractions such as Mashes Sand Beach and Alligator Point Beach. This beachside city has something for everyone including seafood restaurants as well as sights like Bald Point State Park and Silver Lake. All are within a secluded setting.

Sunset over a lake at Panacea, northern Florida, USA | NONE |

Check out reviews of Panacea hotels guests love

Frequently asked questions

How much does a hotel room cost in Panacea?
You can find top hotels in Panacea from $114 with options to suit your budget and needs. If you're looking for an affordable hotel in Panacea that meets all of your requirements, just sort hotels by "Price: low to high" after applying your filters when searching on Hotels.com.
How can I find deals and earn rewards at Panacea hotels?
Discover great deals on Panacea hotel stays with Hotels.com. Take a look at hotel prices mid-week or during the low season as to find those off-peak deals. And make sure to check out our last-minute deals on Panacea hotels.
Can I book Panacea hotels with free cancellation?
To book a refundable Panacea hotel on Hotels.com, just filter hotels by "Property cancellation options" and select "Fully refundable property". Many hotels offer free cancellation, so you can receive a refund if you need to cancel. Some hotels do require cancelling more than 24 hours before check-in, so double-check your booking beforehand.
What hotels do travelers like in Panacea?
Guests like The Panacea Motel.
Can I book a refundable accommodation in Panacea?
If you're looking for the flexibility to change your travel plans to Panacea, most accommodations offer refundable* bookable rates. You can find these accommodations by searching our site and using the "fully refundable" filter to narrow the results down.
Where can I stay in Panacea if I want a vacation home instead of a traditional hotel?
If you want a good alternative to a hotel, browse our selection of 171 vacation homes. In addition, there are 18 apartments and 11 condos.
What will the weather in Panacea be like during my visit?
July and August are typically the warmest months in Panacea when the average temp is 81°F. January and February are the coldest months when the average temperature is 58°F. August and July are the months with the most rain.
Why should I book my Panacea hotel through Hotels.com?
There are lots of reasons to book your Panacea trip with us: our free cancellations on selected hotels gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.

Find out more about Panacea

Discover the Untamed Serenity of Panacea: Where Nature Meets Tranquility

Discover the hidden gem of Panacea, Florida, where pristine beaches meet lush natural landscapes. Nestled along the Gulf Coast, this charming destination invites travelers to explore the tranquil waters of Panacea Springs and enjoy outdoor adventures like kayaking and fishing. Immerse yourself in the area's rich biodiversity at nearby wildlife refuges, or simply relax on sun-kissed shores. With cozy accommodations and a laid-back atmosphere, Panacea is perfect for those seeking a peaceful retreat or a romantic getaway. Experience the serene beauty and welcoming charm of this off-the-beaten-path paradise, where nature and relaxation abound.

Discover great hotels near Panacea

Panacea, Florida offers a mix of charming motels and cozy inns, perfect for travelers seeking a laid-back getaway. Accommodations range from budget-friendly options to comfortable stays, often featuring easy access to the area's natural beauty. Enjoy a relaxed atmosphere and explore the nearby coastline during your visit. Here are some of the most popular hotels with our travelers near Panacea:

  1. Best Western Wakulla Inn & SuitesOpens in a new window: This budget-friendly hotel boasts a commendable guest rating of 8.8 out of 10, making it an ideal choice for adventure-seeking travelers. With its focus on outdoor activities, guests can enjoy a variety of adventure sports such as sailing, snorkeling, and kayaking right nearby. The property features clean and comfortable accommodations, along with an inviting breakfast that provides a delightful start to the day. Visitors appreciate the quiet atmosphere, which is perfect for relaxation after a long journey.
  2. Wildwood InnOpens in a new window: With a rating of 8.6 out of 10, this 3.0-star hotel is perfect for travelers seeking a pet-friendly getaway infused with adventure. It offers a range of recreational activities including fishing and kayaking, making it a great option for those who love the outdoors. Guests enjoy well-maintained rooms and a generous breakfast selection, ensuring a pleasant start to their day. The efficient staff enhances the overall experience, creating a welcoming atmosphere for visitors looking to explore the stunning surroundings.
  3. St James Bay Golf & Pickleball ResortOpens in a new window: This 3.5-star hotel shines with a guest rating of 9.0 out of 10, catering to leisure travelers who appreciate a golf-themed experience. The property features beautifully designed cottages and a top-notch restaurant serving exceptional cuisine. Guests can immerse themselves in a relaxing environment that encourages participation in golf and pickleball. The stunning scenery complements the luxurious setting, making it an ideal retreat for those seeking a blend of relaxation and recreation in a picturesque location.

Where to stay in and around Panacea

Some of the best areas to stay in when visiting Panacea, Florida, are Alligator Point, Crawfordville, and Saint Teresa. Alligator Point offers stunning coastal views and serene beaches, while Crawfordville boasts rich natural attractions and local charm. Saint Teresa is known for its tranquil atmosphere and beautiful waterfront properties. For first-time visitors, Crawfordville is the most appealing choice due to its variety of amenities and access to nature.

  1. Alligator PointOpens in a new window: Alligator Point is a hidden gem for those seeking a laid-back coastal experience. This quaint area is known for its stunning beaches and serene natural surroundings, making it ideal for relaxation and outdoor activities. You can enjoy activities like fishing, kayaking, or simply soaking up the sun on the sandy shores. The nearby wildlife preserve offers opportunities for birdwatching and exploring the local ecosystem, perfect for nature lovers looking to unwind in a tranquil setting.
  2. CrawfordvilleOpens in a new window: Crawfordville serves as a great base for exploring Florida's natural beauty. With its close proximity to parks and rivers, it’s an excellent spot for hiking, canoeing, and enjoying the outdoors. The area is also rich in history, with cultural attractions like historic sites and local art galleries that showcase the community’s heritage. Plus, you’ll find charming shops and local markets that add to the small-town feel, making it a welcoming place for travelers.
  3. Saint TeresaOpens in a new window: If you’re looking for a peaceful retreat, Saint Teresa delivers with its beautiful beaches and inviting atmosphere. This area is perfect for a quiet getaway, where you can enjoy picturesque sunsets and the sounds of the waves. It’s ideal for families and those wanting to escape the hustle and bustle, offering a range of outdoor activities like swimming and beachcombing. The community vibe here is friendly and relaxed, making it a lovely spot to recharge and take in the local scenery.

Things to do in Panacea

Panacea for travelers offers a stunning blend of pristine beaches, lush forests, and serene lakes. Experience thrilling activities like boating with playful dolphins, fishing in tranquil waters, and hiking through scenic trails. As the sun sets, the vibrant colors create a breathtaking backdrop for memorable moments in nature.

  • Ochlockonee River State ParkOpens in a new window – Dive into nature at Ochlockonee River State Park, where you can kayak along serene waters or hike through lush trails. This park is a haven for wildlife enthusiasts and offers a peaceful retreat to enjoy Florida's natural beauty.
  • Alligator Point BeachOpens in a new window – Spend a relaxing day at Alligator Point Beach, where soft sands and gentle waves create the perfect setting for sunbathing, picnicking, or beachcombing. Keep an eye out for dolphins playing in the surf as you soak up the sun.
  • Shell Point BeachOpens in a new window – Shell Point Beach invites you to explore its tidal pools and collect unique seashells. It's an ideal spot for families, with shallow waters perfect for wading and a picturesque landscape that’s great for photography.
  • Wakulla Springs State ParkOpens in a new window – Experience the crystal-clear waters of Wakulla Springs State Park, one of the largest and deepest freshwater springs in the world. Take a guided boat tour to see manatees and alligators in their natural habitat, or enjoy the scenic trails surrounding the spring.
  • St. Marks National Wildlife RefugeOpens in a new window – Discover diverse ecosystems at St. Marks National Wildlife Refuge, where you can hike or bike along trails that lead to stunning views of salt marshes and coastal habitats. Birdwatchers will find this area particularly rewarding, with numerous species to spot.

4 tips for savvy savings when booking a hotel in Panacea

  1. Book for the cheapest times: The best time to visit Panacea for budget-conscious travelers is in January, July, and December, when hotel prices are lower. For a fulfilling experience, it's recommended to stay for at least 2 to 3 days to fully immerse yourself in the area's historical and cultural landmarks. During your visit, you can enjoy the serene beaches, observe playful dolphins, savor fresh seafood, and explore the beautiful nature and wildlife. Additionally, you can unwind with stunning sunsets and partake in fishing or hunting activities, making your trip both relaxing and enriching—all while keeping it affordable and great value for money.
  2. Look for last-minute deals on Hotels.com: To explore options for Panacea, start by checking the DealsOpens in a new window and Last-Minute DealsOpens in a new window sections on Hotels.com, where you may discover discounted rates on hotels as your travel date approaches. By enabling email alerts or push notifications, you could find out about special last-minute promotions, ensuring you stay informed about potential savings. Additionally, utilize the Smart ShoppingOpens in a new window tool available via the app to compare hotel prices and amenities. This feature helps you track your favorite hotels, so you're more likely to find our best options and book a convenient last-minute getaway.
  3. Be flexible with dates: Prices can fluctuate based on various factors like the hotel's location, star rating, and the time of year. Being flexible with your travel dates may help you find a better deal at the Panacea hotel. If you're interested in a unique experience, boutique hotels can provide a more personalized stay and sometimes offer better value. When you book through Hotels.com, we’ll inform you if the price for your chosen dates is above or below the average. If the price leans towards the higher end, we can suggest alternative dates that might be more budget-friendly, which could help you find a great rate.
  4. Consider your location: Staying near major attractions or downtown areas can provide convenience, but it often comes with a higher price tag. For more budget-friendly options, you might want to consider hotels in neighborhoods that are a bit further out, allowing you to balance cost with easy access to the sights you want to see. Independent hotels located farther away may also offer a more authentic experience and are usually more likely to be affordable.

Best time to go to Panacea

Panacea experiences its lowest average temperature in January, at 53.6°F (12.0°C), while July to August are the hottest months, with an average temperature of 81.7°F (27.6°C). August is typically the wettest month. If you’re looking to soak up the lively atmosphere in Panacea, April, June, and July are the peak months to visit, bustling with fellow travelers. During this peak period, the weather is mostly sunny, with light to moderate rainfall. However, if you prefer a more relaxed experience, October to December are perfect for a quieter getaway, marked by light rainfall and mostly sunny conditions.

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