Hotels in Guadalupe, Panama

Search & Compare Guadalupe Hotels

Hotels.com® Rewards

Collect 10 nights, get 1 free night

And look out for Secret Prices on select hotels

  • Pay now or later on most rooms
  • Free cancellation on most rooms
  • Price Guarantee

Best hotels in Guadalupe

Guadalupe overview

There's plenty to explore, including local sights like Altos De Campana National Park. Guadalupe is an inviting destination that has something for everyone.

Where to stay in Guadalupe

Whether you're planning to stay for a night or for the week, the area around Guadalupe has accommodations to fit every need. Search for hotels in Guadalupe with Hotels.com by checking our online map. Our maps display the areas and neighborhoods around all Guadalupe hotels so you can see how close you are from landmarks and attractions, and then refine your search within the larger area. The best Guadalupe hotel deals are here with our lowest price guarantee.

How to get to Guadalupe

Fly in to Panama City (PAC-Marcos A. Gelabert Intl.), 18.8 mi (30.3 km) from downtown Guadalupe.

When to visit Guadalupe

Wondering what time of year to travel, or what clothes to pack? Here are seasonal norms to help you with your planning:

Seasonal temperature averages
  • January-March: 91°F day, 74°F night
  • April-June: 91°F day, 75°F night
  • July-September: 87°F day, 74°F night
  • October-December: 88°F day, 74°F night
Seasonal rainfall averages
  • January-March: 0.24 inches
  • April-June: 0.51 inches
  • July-September: 0.75 inches
  • October-December: 1.06 inches