Polyxeni Hotel is close to Glicorisa Beach, Folklore Museum of Samos, and Agia Triada Monastery. Additional area attractions include Natural History Museum of the Aegean and Heraion of Samos.
The hotel offers a bar/lounge. Additional amenities include multilingual staff and tour/ticket assistance.
The 21 air-conditioned guestrooms at Polyxeni Hotel include hair dryers.